MACA plus Pygeum Ingredients & Drug Interactions
What is this page for?
First and foremost: checking MACA plus Pygeum against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
MACA plus Pygeum is a dietary supplement by Wonder Laboratories with 2 active ingredients. Its ingredients are commonly taken for low libido and sexual function, energy and stamina, menopause symptoms.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of MACA plus Pygeum by Wonder Laboratories
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product has 2 active ingredients: maca root extract and pygeum bark extract. Maca is a plant used traditionally to support various aspects of health, while pygeum comes from the bark of an African tree and is primarily used for prostate health in men.
The capsule also contains inactive ingredients — cellulose, gelatin, magnesium stearate, and silica — which serve as binders and fillers.
Does it work?
Strong evidence
Pygeum is likely effective for benign prostate hyperplasia (BPH), an enlarged prostate common in older men. Maca, on the other hand, has been studied for several uses — including amenorrhea (missed periods), anemia, antidepressant-related sexual dysfunction, athletic performance, and bone health — but the evidence isn't strong enough to say it works for any of them.
If you're taking this for prostate support, pygeum is your active ingredient; if you're hoping for something else, the evidence doesn't back it up.
How safe is it?
Well-documented data
Both ingredients are generally well tolerated in the short term, but long-term safety data in supplement amounts is limited for both. Maca may cause stomach pain if it's fresh or uncooked.
Pygeum has occasionally been linked to nausea and belly pain in studies, though those rates were similar to placebo. Neither ingredient has been studied enough to call them safe during pregnancy or breastfeeding — the data advises against use in both cases.
Meds to double-check
No known interactions
No interactions are documented for the ingredients we could check in this product. Still, run your exact medications through the checker below or ask your pharmacist before starting, just to be thorough.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
If you're a man with an enlarged prostate, pygeum may help — that's the one ingredient here with solid evidence. If you're taking this for other reasons, talk with your pharmacist first, since the evidence for maca's other uses isn't established.
Avoid this product if you're pregnant or breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about MACA plus Pygeum, straight from the product label.
| Brand | Wonder Laboratories |
|---|---|
| Net contents | 180 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2024 |
| DSLD ID | 315673 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult Male (18-50 Years), Seniors/Mature (>50 Years) - Men ONLY, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for MACA plus Pygeum by Wonder Laboratories, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Maca Root Extract | 300 mg | -- |
| Pygeum Bark Extract | 40 mg | -- |
Other ingredients: Cellulose, Gelatin, Magnesium Stearate, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take 1 capsule twice daily.
Precautions
Tamper evident: Do not use this product if imprinted foil seal under cap is broken or missing.
Keep out of reach of children.
Formulation
Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)
Conforms up to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.
Nutritionally supports healthy prostate function
Gluten free
Made in USA
Storage
Keep tightly closed. Store at room temperature: 59 degrees-86 degrees F (15 degrees to 30 degrees C).
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General Statements
Formula 051
Reorder #0512
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
MACA plus Pygeum by Wonder Laboratories label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in MACA plus Pygeum by Wonder Laboratories
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Maca Root Extract
No knowninteractions
Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire an...
Maca Root Extract monograph & interactionsPygeum Bark Extract
No knowninteractions
Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some st...
Pygeum Bark Extract monograph & interactionsOther (inactive) ingredients: Cellulose, Gelatin, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.
MACA plus Pygeum by Wonder Laboratories Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in MACA plus Pygeum. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for MACA plus Pygeum, from the product label.
Wonder Laboratories
See all Wonder Laboratories products- Name
- Wonder Laboratories
- Street Address
- 115 S.C.T. Ct.
- City
- White House
- State
- TN
- ZipCode
- 37188
MACA plus Pygeum by Wonder Laboratories: Common Questions
Does MACA plus Pygeum by Wonder Laboratories interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does pygeum actually do?
Will maca help my energy or sexual function?
What side effects should I watch for?
Can I take this if I'm pregnant or breastfeeding?
Are there any fillers in this capsule?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if MACA plus Pygeum is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind MACA plus Pygeum’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Maca
Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire and some menopause symptoms, but the evide...
Read the full Maca monograph → Herb & supplement monographPygeum
Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some studies suggest modest benefit for these s...
Read the full Pygeum monograph →Sources & How We Checked
MACA plus Pygeum's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Maca 1 reference
- Valerio, L. G., Jr. and Gonzales, G. F. Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis. Toxicol.Rev 2005;24(1):11-35. PubMed
Pygeum 3 references
- Ishani A, MacDonald R, Nelson D, et al. Pygeum africanum for the treatment of patients with benign prostatic hyperplasia: a systematic review and quantitative meta-analysis. Am J Med 2000;109:654-64.. PubMed
- Wilt T, Ishani A, Mac Donald R, et al. Pygeum africanum for benign prostatic hyperplasia. Cochrane Database Syst Rev 2002;CD001044.. PubMed
- Andro M and Riffaud J. Pygeum africanum extract for the treatment of patients with benign prostatic hyperplasia: a review of 25 years of published experience. Curr Ther Res 1995;56(8):796-817. DOI
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC