No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Madder Root Ingredients & Drug Interactions

by TerraVita

Madder Root label
See full label image
Liquid Category: Botanical
No known interaction
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Madder Root against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Madder Root is a dietary supplement by TerraVita with 1 active ingredient. Its ingredients are commonly taken for kidney and bladder stones, urinary tract complaints, menstrual problems.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

Jump to a section

HelloPharmacist Scorecard of Madder Root by TerraVita

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Madder Root Glycerite Liquid Extract. Madder root has been used traditionally, but the safety profile is what matters here.

The liquid is prepared in glycerin, which is an inactive ingredient that helps preserve and deliver the extract.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Madder product and its label doesn't state a use — see Madder's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't have effectiveness ratings on file for madder root. The evidence to support its use as a supplement isn't established in our data.

The evidence, ingredient by ingredient Madder

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Here's what you need to know: some madder compounds have shown genotoxic effects — meaning they may damage genetic material — and there's concern about possible cancer risk, so it's best avoided as a supplement altogether. Madder has traditionally been used to stimulate menstruation and may affect the uterus, which is why it's unsafe in pregnancy.

While breastfeeding, safety is unknown and its pigments can pass into body fluids, so it's unsafe then too. On a lighter note, orally madder can turn your urine, saliva, and sweat red, and there's some concern it could stain contact lenses — so be cautious if you wear them.

Handling madder topically has caused contact dermatitis in some people.

Side effects, ingredient by ingredient Madder

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for this ingredient with any medications.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Because of the genotoxic concerns and possible cancer risk, madder root is best avoided as a supplement. If you're pregnant or breastfeeding, it's unsafe.

If you've been considering it for a specific reason, talk to your pharmacist or doctor — there may be a better option for what you're trying to do.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Madder Root, straight from the product label.

Brand TerraVita
Barcode (UPC) 064435226879
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Dec 13, 2022
DSLD ID 279669
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Madder Root by TerraVita, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
25 Drop(s)
Maximum serving Sizes:
40 Drop(s)
Servings per container
227
UPC/BARCODE
064435226879
IngredientAmount% DV
Madder Root Glycerite Liquid Extract0.13 mL--

Other ingredients: Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Copyright 2018 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Formula

Glycerite liquid extract (1:5)

Formulation

Alcohol free No flavor

Suggested/Recommended/Usage/Directions

Suggested Use: Take 25-40 drops of extract in a small amount of warm water 3-4 times daily. Shake well before using.

Precautions

Keep away from children.

Do not use if safety seal around cap is broken or missing.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Madder Root by TerraVita label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Madder Root label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Madder Root by TerraVita

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size25 Drop(s) Dosage formLiquid Servings per container227 Amounts shown are per serving.

Madder Root Glycerite Liquid Extract

No known
interactions
0.13 mL per serving

Madder is a plant whose root has long been used as a red dye and in traditional medicine, mostly for kidney and urinary problems. There is very little...

Madder Root Glycerite Liquid Extract monograph & interactions

Other (inactive) ingredients: Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Madder Root by TerraVita Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Madder Root. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Madder Root, from the product label.

TerraVita

See all TerraVita products
Name
ZooScape LLC
Phone Number
844-449-0444
Web Address
www.ZooScape.com
Pharmacist Counseling Corner

Madder Root by TerraVita: Common Questions

Does Madder Root by TerraVita interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Madder Root. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Madder Root contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's the red urine about?
Madder can turn your urine, saliva, and even perspiration red — it's a pigment effect. There's also some concern it could stain contact lenses, so be cautious if you wear them.
Can I take this while pregnant?
No. Madder has traditionally been used to stimulate menstruation and may affect the uterus, so it's unsafe during pregnancy.
Is it safe while breastfeeding?
No. Safety isn't known, and its pigments can pass into body fluids, so it's unsafe while breastfeeding.
What's the cancer concern?
Some madder compounds have shown genotoxic effects — meaning they may damage genetic material — and there's concern about possible cancer risk. Because of that, madder is best avoided as a supplement.
Can handling madder cause a rash?
Yes. Contact dermatitis has been reported in people who handled madder, including while gardening, so be cautious if you're touching it directly.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Madder Root is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Madder Root label
Go deeper

The Full Monographs Behind Madder Root’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Madder

Madder is a plant whose root has long been used as a red dye and in traditional medicine, mostly for kidney and urinary problems. There is very little reliable human evidence that it works,...

Read the full Madder monograph →
Sources

Sources & How We Checked

Madder Root's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Madder 4 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999.
  4. Castelain M, Ducombs G. Contact dermatitis from madder. Contact Dermatitis 1988;19(3):228-229. PubMed

See these in context on the Madder monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team