Magnolia Extract Honokiol + Magnolol 90% Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Magnolia Extract Honokiol + Magnolol 90% against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Magnolia Extract Honokiol + Magnolol 90% is a dietary supplement by Allergy Research Group with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, sleep problems, digestive upset.Based on those ingredients, 351 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Magnolia Bark Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Magnolia Extract Honokiol + Magnolol 90% by Allergy Research Group
Ask about any prescription or over-the-counter medication and we check it for interactions with Magnolia Extract Honokiol + Magnolol 90% by Allergy Research Group — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Magnolia Extract Honokiol + Magnolol 90% by Allergy Research Group
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: magnolia bark extract standardized to 90% honokiol and magnolol, the two main compounds in magnolia that research suggests drive its effects. The capsule itself is made up of inactive ingredients—the plant-based capsule material (hydroxypropyl methylcellulose), a filler (microcrystalline cellulose), and L-leucine—but these don't contribute to the product's therapeutic action.
Does it work?
Insufficient evidence
Magnolia extract is possibly effective for gingivitis (gum inflammation). For allergic rhinitis (hay fever), anxiety, and dental plaque buildup, the evidence we hold isn't strong enough to say whether it works—these fall into insufficient reliable evidence territory.
If you're considering this for one of those conditions, talk with your doctor about whether the current research supports a trial.
How safe is it?
Well-documented data
Taken by mouth, magnolia is generally well tolerated. That said, human safety data is limited, especially for long-term use.
In a few trial participants taking a combination product with magnolia, there were scattered reports of sexual dysfunction, shaking hands, numbness around the mouth, fatigue, and headache—but it's unclear whether magnolia itself was responsible. Magnolia is not recommended in pregnancy; safety data advises against it because of concerns it may affect the uterus.
There isn't reliable safety information for breastfeeding, so it's best avoided then too. If you're pregnant, nursing, or planning either, talk with your doctor or pharmacist before taking this.
Meds to double-check
Moderate interaction found
Check your medications against this product if you take blood thinners or antiplatelet drugs (like warfarin, aspirin, or clopidogrel)—magnolia may raise bleeding risk. Also double-check any CNS depressants: sedating drugs, sleep aids, benzodiazepines, or opioids may have deeper effects when paired with magnolia.
Your doctor or pharmacist can confirm whether it's safe to use together.
The bottom line
Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Magnolia extract may help with gingivitis, but the evidence for other common uses—hay fever, anxiety, plaque—isn't established. It's generally well tolerated, but it can thin the blood and deepen sedation, so if you take blood thinners, antiplatelet drugs, or sedating medications, check with your doctor or pharmacist first.
It's not recommended in pregnancy or while breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Magnolia Extract Honokiol + Magnolol 90%, straight from the product label.
| Brand | Allergy Research Group |
|---|---|
| Barcode (UPC) | 713947763906 |
| Net contents | 120 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Mar 22, 2024 |
| DSLD ID | 304254 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Magnolia Extract Honokiol + Magnolol 90% by Allergy Research Group, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Magnolia Bark Extract | 200 mg | -- |
Other ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, L-Leucine
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Magnolia Extract provides an extract containing honokiol and magnolol concentrated to 90%.
Suggested/Recommended/Usage/Directions
Suggested use As a dietary supplement, 1 capsule daily, or as directed by a healthcare practitioner.
Precautions
Warning: May cause drowsiness. Do not operate a motor vehicle or other machinery after ingesting.
Not recommended during pregnancy.
To report any adverse reactions, call 1-833-914-2097.
Storage
Keep in a cool, dry place, tightly capped. Avoid high temperatures for extended periods.
FDA Statement of Identity
Dietary Supplement
Formulation
Hypoallergenic
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Magnolia Extract Honokiol + Magnolol 90% by Allergy Research Group label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Magnolia Extract Honokiol + Magnolol 90% by Allergy Research Group
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.
Magnolia Bark Extract
Interacts with351 drugs
Magnolia bark and flower buds have a long history in traditional Chinese and Japanese medicine, often for stress, sleep, and digestion. Modern human r...
Magnolia Bark Extract monograph & interactionsOther (inactive) ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, L-Leucine. These complete the product’s ingredient list but are not active constituents.
Magnolia Extract Honokiol + Magnolol 90% by Allergy Research Group Drug Interactions
HelloPharmacist Interaction Report
Magnolia Extract Honokiol + Magnolol 90% by Allergy Research Group has documented interactions through its magnolia bark extract with two major medication categories.
The most serious concern is with blood thinners and antiplatelet drugs (like warfarin and aspirin): magnolia's active compounds may reduce clotting and add to these drugs' effects, raising bleeding risk. This is a Moderate-severity interaction.
Read the full breakdown — every affected drug type, severity by severity
CNS depressants—sedating medications like benzodiazepines, sleep aids, and opioids—may also have Moderate interactions with magnolia. The extract has sedative properties, and taking it alongside these drugs could deepen drowsiness or other CNS-dampening effects.
Altogether, these interactions span 351 individual medications.
Before you start this product, run your exact medications through the checker on this page, especially if you take any blood thinner, antiplatelet agent, or sedating drug. Your doctor or pharmacist can tell you whether it's safe to combine magnolia with what you're on.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Magnolia Extract Honokiol + Magnolol 90%?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Magnolia Extract Honokiol + Magnolol 90% interact with 351 drugs. Click any drug to see the details.
1 of the 1 ingredient in Magnolia Extract Honokiol + Magnolol 90% interact with drugs. Each result below shows which ingredient is responsible. Magnolia Bark Extract
AbciximabReoPro
How Abciximab interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Magnolia Bark Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Magnolia Bark Extract + Abrocitinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Magnolia Bark Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acepromazine interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Magnolia Bark Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Magnolia Bark Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Chlorzoxazone, Codeine interactionAcetaminophen, CodeineTylenol No.3, Tylenol w/ Codeine
How Acetaminophen, Codeine interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Codeine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Codeine, MethocarbamolAcetaminophen, Codeine, Methocarbamol, Robaxacet 8
How Acetaminophen, Codeine, Methocarbamol interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Codeine, Methocarbamol interactionAcetaminophen, Dichloralantipyrine, IsomethepteneAmidrine, Midchlor, Migquin, Migratine
How Acetaminophen, Dichloralantipyrine, Isometheptene interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Dichloralantipyrine, Isometheptene interactionAcetaminophen, Dichloralphenazone, IsomethepteneMidrin
How Acetaminophen, Dichloralphenazone, Isometheptene interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Dichloralphenazone, Isometheptene interactionAcetaminophen, Dichlorophenazone, IsometheptaneIsocom
How Acetaminophen, Dichlorophenazone, Isometheptane interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Dichlorophenazone, Isometheptane interactionAcetaminophen, DiphenhydramineTylenol PM, Tylenol PM Ex Strength
How Acetaminophen, Diphenhydramine interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Diphenhydramine interactionAcetaminophen, Diphenhydramine, PseudoephedrineChildren's Tylenol Allergy, Cold Control, Contac Night Allergy Relief
How Acetaminophen, Diphenhydramine, Pseudoephedrine interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Diphenhydramine, Pseudoephedrine interactionAcetaminophen, HydrocodoneAnexsia, Anodynos DHC, Azdone, Co-Gesic, Doucet, Lorcet +9 more
How Acetaminophen, Hydrocodone interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Hydrocodone interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Magnolia Bark Extract + Acetaminophen, Ibuprofen interactionAcetaminophen, MeperidineDemerol APAP
How Acetaminophen, Meperidine interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Meperidine interactionAcetaminophen, OxycodonePercocet, Roxicet, Tylox, Xartemis XR
How Acetaminophen, Oxycodone interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Oxycodone interactionAcetaminophen, PentazocineTalacen
How Acetaminophen, Pentazocine interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Pentazocine interactionAcetaminophen, PropoxypheneDarvocet-N 100, Darvocet-N 50, E-Lor, Wygesic
How Acetaminophen, Propoxyphene interacts with Magnolia Extract Honokiol + Magnolol 90% — through 1 ingredient. Tap an ingredient for the detail:
Magnolia Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Bark Extract + Acetaminophen, Propoxyphene interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Magnolia Extract Honokiol + Magnolol 90% with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Magnolia Bark Extract
Anticoagulant/Antiplatelet Drugs
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
In vitro research shows that the chemicals magnolol and honokiol, isolated from magnolia bark, inhibit platelet aggregation that is experimentally induced by collagen and arachidonic acid. However, they do not inhibit platelet aggregation that is induced by adenosine diphosphate, platelet-activating factor, or thrombin. This interaction has not been reported in humans.
Cns Depressants
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
In vitro and animal research shows that constituents extracted from magnolia bark, especially honokiol and magnolol, have sedative effects. These effects may be due to the inhibition of catecholamine release and modulation of gamma-aminobutyric acid-A (GABA-A) receptors.
Brand information
Manufacturer and brand details for Magnolia Extract Honokiol + Magnolol 90%, from the product label.
Allergy Research Group
See all Allergy Research Group products- Name
- Allergy Research Group
- City
- South Salt Lake
- State
- UT
- ZipCode
- 84115
- Phone Number
- 800.545.9960
- Web Address
- www.allergyresearchgroup.com
Magnolia Extract Honokiol + Magnolol 90% by Allergy Research Group: Common Questions
Does Magnolia Extract Honokiol + Magnolol 90% by Allergy Research Group interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this while I'm pregnant?
Is it safe to breastfeed while taking magnolia extract?
What side effects have been reported?
Does magnolia actually work for gingivitis?
What are honokiol and magnolol?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Magnolia Extract Honokiol + Magnolol 90% is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Magnolia Extract Honokiol + Magnolol 90%’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Magnolia Extract Honokiol + Magnolol 90%'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 9 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Magnolia 9 references
- Kuribara H, Kishi E, Hattori N, et al. The anxiolytic effect of two oriental herbal drugs in Japan attributed to honokiol from magnolia bark. J Pharm Pharmacol 2000;52:1425-9. PubMed
- Tachikawa E, Takahashi M, Kashimoto T. Effects of extract and ingredients isolated from Magnolia obovata thunberg on catecholamine secretion from bovine adrenal chromaffin cells. Biochem Pharmacol 2000;60:433-40. PubMed
- Jung KY, Kim DS, Oh SR, et al. Magnone A and B, novel anti-PAF tetrahydrofuran lignans from the flower buds of Magnolia fargesii. J Nat Prod 1998;61:808-11.
- Garrison R, Chambliss WG. Effect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trial. Altern Ther Health Med 2006;12:50-4.
- Teng CM, Chen CC, Ko FN, et al. Two antiplatelet agents from Magnolia officinalis. Thromb Res 1988;50:757-65. PubMed
- Ghys K, De Palma A, Vandevenne A, Werbrouck J, Goossens A. Magnolia officinalis bark extract, a recently identified contact allergen in 'anti-ageing' cosmetics. Contact Dermatitis. 2015 Aug;73(2):130-2.
- Raison-Peyron N, Césaire A, Du-Thanh A, Dereure O. Allergic contact dermatitis caused by Magnolia officinalis bark extract in a facial anti-ageing cream. Contact Dermatitis. 2015 Jun;72(6):416-7.
- Nilausen TD, Johansen JD, Thyssen JP. Allergic contact dermatitis of the face caused by Magnolia officinalis bark extract. Contact Dermatitis. 2016;75(6):385-87.
- Amat-Samaranch V, López-Sánchez C, Tubau C, Puig L, Serra-Baldrich E. Vulvar allergic contact dermatitis caused by Magnolia officinalis bark extract. Contact Dermatitis 2022;87(1):96-97.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC