No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Mastic Gum 500 mg Ingredients & Drug Interactions

by Best Naturals

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Mastic Gum 500 mg is a dietary supplement by Best Naturals with 1 active ingredient. Its ingredients are commonly taken for indigestion and stomach upset, stomach ulcers and h. pylori support, oral and gum health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Mastic Gum 500 mg by Best Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: mastic gum powder, a traditional resin from the mastic tree. It's been used for centuries, especially in Mediterranean folk medicine.

The capsule itself is made from gelatin and contains inactive ingredients — maltodextrin, magnesium stearate, and silicon dioxide — which help bind and fill the capsule.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Mastic's overall clinical evidence instead.

Moderate

Some clinical evidence supports Mastic for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Dyspepsia — rated "Possibly Effective" (Natural Medicines).

Mastic gum is possibly effective for dyspepsia, a term for indigestion or stomach discomfort. For brittle nails, nonalcoholic fatty liver disease (NAFLD), and cancer, the evidence isn't established well enough to rate how well it works.

If you're thinking about it for one of those conditions, talk with your doctor about what the science actually shows and whether it's worth trying.

The evidence, ingredient by ingredient Mastic

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

When taken by mouth, mastic gum is generally well tolerated, though the safety data for supplement-strength doses are limited. Rarely, people have reported nausea, diarrhea, or constipation — one case of constipation resolved within two days of stopping.

There's not enough safety information to recommend medicinal amounts during pregnancy or while breastfeeding; talk with your doctor or pharmacist if you're in either situation.

Side effects, ingredient by ingredient Mastic

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for mastic gum. Even so, check your exact medications with the search tool on this page or ask your pharmacist before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

Mastic gum is a reasonable option if you're looking for something possibly effective for indigestion. It's generally well tolerated and has no documented interactions with medications.

Because safety data on supplement doses are limited and pregnancy/breastfeeding safety isn't established, run it by your pharmacist first, especially if you're pregnant, nursing, or managing a health condition.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Mastic Gum 500 mg, straight from the product label.

Brand Best Naturals
Barcode (UPC) 817716012599
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 269877
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Mastic Gum 500 mg by Best Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
817716012599
IngredientAmount% DV
Mastic Gum, Powder1000 mg--

Other ingredients: Maltodextrin, Magnesium Stearate, Silicon Dioxide, Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Best Naturals Mastic Gum contains natural tree stem mastic gum (Pistacia lentiscus), a resinous compound, from a shrub-like tree grown mainly in Greece and Turkey. Resins, such as the triterpene mastic acid, make up 90 percent of the gum. Mastic gum contains a number of trace elements like sodium, magnesium, potassium, iron, calcium and manganese. Certain research publications indicate that it may help supports the following: Supports gastrointestinal and oral health Supports healthy stomach lining supports digestive discomfort

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take two (2) capsules per day with water or juice before breakfast or as directed by your qualified healthcare professional.

Precautions

Keep out of the reach of children.

Do not use if safety seal is broken or missing.

Caution: For adults only, if you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Storage

Keep in cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

Made in USA

GMP Good Manufacturing Practice Product

Formulation

Premium formula

3rd party lab tested

No artificial color, flavor or sweetener, no preservatives, no sugar, no starch, no corn, no soy, no egg, no lactose, no gluten, no wheat, no yeast, no fish.

FDA Statement of Identity

Dietary Supplement

See for yourself

Mastic Gum 500 mg by Best Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Mastic Gum 500 mg by Best Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Mastic Gum, Powder

No known
interactions
1000 mg per serving

Mastic is a resin from the mastic tree that has a long history of use for digestive complaints and oral health. Some small studies suggest it may help...

Mastic Gum, Powder monograph & interactions

Other (inactive) ingredients: Maltodextrin, Magnesium Stearate, Silicon Dioxide, Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Mastic Gum 500 mg by Best Naturals Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Mastic Gum 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Mastic Gum 500 mg, from the product label.

Best Naturals

See all Best Naturals products
Name
Best Naturals
Street Address
PO Box 394
City
Kenilworth
State
NJ
ZipCode
07033
Phone Number
1-877-659-6004
Web Address
www.shopbestnaturals.com
Pharmacist Counseling Corner

Mastic Gum 500 mg by Best Naturals: Common Questions

Does Mastic Gum 500 mg by Best Naturals interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Mastic Gum 500 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Mastic Gum 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is mastic gum and where does it come from?
Mastic gum is a resin from the mastic tree and has been used for centuries, especially in Mediterranean traditional medicine. This product contains mastic gum powder in capsule form.
Can I take this if I'm pregnant or breastfeeding?
There's not enough safety information to recommend medicinal amounts during pregnancy or breastfeeding. Talk with your doctor or pharmacist about whether it's right for you in either situation.
What side effects might I notice?
Most people tolerate it well when taken by mouth. Rarely, nausea, diarrhea, or constipation have been reported — one case of constipation stopped two days after stopping the product. If anything unusual happens, let your pharmacist know.
Does mastic gum actually work for indigestion?
It's possibly effective for dyspepsia (indigestion or stomach discomfort). For other uses like brittle nails or fatty liver disease, the evidence isn't strong enough to say how well it works.
Should I worry about it interacting with my medications?
No interactions are documented for mastic gum. That said, check your exact medications with the tool on this page or ask your pharmacist before you start, just to be sure.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Mastic Gum 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Mastic Gum 500 mg label
Go deeper

The Full Monographs Behind Mastic Gum 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Mastic Gum 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Mastic 5 references
  1. Kaliora, A. C., Stathopoulou, M. G., Triantafillidis, J. K., Dedoussis, G. V., and Andrikopoulos, N. K. Chios mastic treatment of patients with active Crohn's disease. World J Gastroenterol. 2-7-2007;13(5):748-753. PubMed
  2. Dabos, K. J., Sfika, E., Vlatta, L. J., and Giannikopoulos, G. The effect of mastic gum on Helicobacter pylori: a randomized pilot study. Phytomedicine. 2010;17(3-4):296-299. PubMed
  3. Dabos, K. J., Sfika, E., Vlatta, L. J., Frantzi, D., Amygdalos, G. I., and Giannikopoulos, G. Is Chios mastic gum effective in the treatment of functional dyspepsia? A prospective randomised double-blind placebo controlled trial. J Ethnopharmacol. 2-3-20 PubMed
  4. Hazan Z, Adamsky K, Lucassen A, Levin LA. A first-in-human phase 1 randomized single and multiple ascending dose study of RPh201 in healthy volunteers. Clin Pharmacol Drug Dev. 2020;9(3):366-74. PubMed
  5. Moraschini V, Kischinhevsky ICC, Calasans-Maia MD, et al. Ineffectiveness of ozone therapy in nonsurgical periodontal treatment: a systematic review and metaanalysis of randomized clinical trials. Clin Oral Investig 2020;24(6):1877-1888. PubMed

See these in context on the Mastic monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring