No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Mastic Gum 500 mg Ingredients & Drug Interactions

by Nova Nutritions

Capsule Category: Fat/fatty Acid
No known interaction
The interaction bottom line No known interaction

Mastic Gum 500 mg is a dietary supplement by Nova Nutritions with 1 active ingredient. Its ingredients are commonly taken for indigestion and stomach upset, stomach ulcers and h. pylori support, oral and gum health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Mastic Gum 500 mg by Nova Nutritions

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: mastic gum, a resin from the mastic tree traditionally used in Mediterranean and Middle Eastern medicine. Each capsule delivers 500 mg.

The capsule itself and other inactive ingredients — gelatin, maltodextrin, silica, and magnesium stearate — are excipients that help deliver and stabilize the active ingredient.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: supports the stomach and duodenum.
  • We looked for evidence on: Dyspepsia, Helicobacter pylori, Peptic ulcers, Gastritis, Duodenitis, Gastrointestinal inflammation.
  • The strongest evidence on file: Mastic is rated "Possibly Effective" for Dyspepsia (Natural Medicines).
  • Also on file: Mastic is rated "Insufficient Reliable Evidence To Rate" for Helicobacter pylori, Peptic ulcers.

Mastic gum is possibly effective for indigestion (dyspepsia), based on available evidence. For brittle nails, nonalcoholic fatty liver disease, and cancer, the evidence is too thin to rate — we simply don't have enough reliable data to say whether it works.

If you're considering it for indigestion, talk with your pharmacist or doctor about whether it's a fit for your situation.

The evidence, ingredient by ingredient Mastic

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taken by mouth, mastic gum is generally well tolerated, though safety data from supplement-strength doses are limited. Nausea, diarrhea, and constipation have been rarely reported; in one reported case, constipation stopped two days after someone stopped taking it.

During pregnancy and while breastfeeding, there isn't enough safety information — the data advise against medicinal amounts. Talk with your doctor or pharmacist for personalized guidance if you're pregnant or nursing.

Side effects, ingredient by ingredient Mastic

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for mastic gum. That said, we have limited safety data at supplement strength, so mention this product to your pharmacist when you fill any new prescriptions.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Mastic gum may help with indigestion if the evidence behind it appeals to you. If you're pregnant, nursing, or have a history of digestive upset, check with your pharmacist first.

No medication interactions are documented, but run your exact medications through the checker below to be thorough.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Mastic Gum 500 mg, straight from the product label.

Brand Nova Nutritions
Barcode (UPC) 732363270737
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jun 24, 2020
DSLD ID 229298
Product type Fat/fatty Acid
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Mastic Gum 500 mg by Nova Nutritions, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
732363270737
IngredientAmount% DV
Mastic Gum1000 mg--

Other ingredients: Gelatin, Maltodextrin, Silica, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Mastic Gum contains natural tree stem mastic gum (Pistacia lentiscus), a resinous compound, from a shrub-like tree grown mainly in Greece and Turkey. Resins, such as the triterpene mastic acid, make up 90 percent of the gum. Mastic gum contains a number of trace elements like sodium, magnesium, potassium, iron, calcium and manganese. Mostly composed of resinous gum and volatile oils, mastic has been used for centuries by traditional healers for stomach distress.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take two (2) capsules per day with water or juice before breakfast or as directed by your qualified healthcare professional.

Precautions

Keep out of the reach of children.

Do not use if safety seal is broken or missing.

Caution: For adults only, if you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Storage

Keep in cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Supports the stomach & duodenum

Free of: Artificial color, preservatives, sugar, starch, milk, corn, gluten, wheat, yeast, fish.

GMP Good Manufacturing Practice Product Made in USA

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

GMP Good Manufacturing Practice Product Made in USA

See for yourself

Mastic Gum 500 mg by Nova Nutritions label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Mastic Gum 500 mg by Nova Nutritions

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Mastic Gum

No known
interactions
1000 mg per serving

Mastic is a resin from the mastic tree that has a long history of use for digestive complaints and oral health. Some small studies suggest it may help...

Mastic Gum monograph & interactions

Other (inactive) ingredients: Gelatin, Maltodextrin, Silica, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Mastic Gum 500 mg by Nova Nutritions Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Mastic Gum 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Mastic Gum 500 mg, from the product label.

Nova Nutritions

See all Nova Nutritions products
Name
Nova Nutritions
City
Scotch Plains
State
New Jersey
ZipCode
07076
Web Address
www.novanutritions.com
Pharmacist Counseling Corner

Mastic Gum 500 mg by Nova Nutritions: Common Questions

Does Mastic Gum 500 mg by Nova Nutritions interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Mastic Gum 500 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Mastic Gum 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does mastic gum actually work?
For indigestion, the evidence suggests it's possibly effective — it's not a slam dunk, but it's been studied. For other uses like brittle nails or fatty liver disease, we don't have enough reliable data to say whether it works. Your pharmacist can help you decide if it's worth trying for your specific situation.
Can I take this if I'm pregnant or breastfeeding?
Not enough safety information exists at medicinal doses — the data advise against it. If you're pregnant or nursing and interested in mastic gum, talk with your doctor or pharmacist about whether it's right for you.
What side effects should I watch for?
Nausea, diarrhea, and constipation have been rarely reported when taken by mouth. Most people tolerate it well, but if you notice any digestive changes, stop and let your pharmacist know.
Is mastic gum natural?
Yes — it's a resin from the mastic tree, used traditionally for centuries. This product is the supplement-strength form, so safety data are more limited than for traditional food amounts.
Does it interact with my medications?
No interactions are documented in our data. Use the medication checker on this page to verify your exact prescriptions, but you're starting from a clean slate here.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Mastic Gum 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Mastic Gum 500 mg label
Go deeper

The Full Monographs Behind Mastic Gum 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Mastic Gum 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Mastic 5 references
  1. Kaliora, A. C., Stathopoulou, M. G., Triantafillidis, J. K., Dedoussis, G. V., and Andrikopoulos, N. K. Chios mastic treatment of patients with active Crohn's disease. World J Gastroenterol. 2-7-2007;13(5):748-753. PubMed
  2. Dabos, K. J., Sfika, E., Vlatta, L. J., and Giannikopoulos, G. The effect of mastic gum on Helicobacter pylori: a randomized pilot study. Phytomedicine. 2010;17(3-4):296-299. PubMed
  3. Dabos, K. J., Sfika, E., Vlatta, L. J., Frantzi, D., Amygdalos, G. I., and Giannikopoulos, G. Is Chios mastic gum effective in the treatment of functional dyspepsia? A prospective randomised double-blind placebo controlled trial. J Ethnopharmacol. 2-3-20 PubMed
  4. Hazan Z, Adamsky K, Lucassen A, Levin LA. A first-in-human phase 1 randomized single and multiple ascending dose study of RPh201 in healthy volunteers. Clin Pharmacol Drug Dev. 2020;9(3):366-74. PubMed
  5. Moraschini V, Kischinhevsky ICC, Calasans-Maia MD, et al. Ineffectiveness of ozone therapy in nonsurgical periodontal treatment: a systematic review and metaanalysis of randomized clinical trials. Clin Oral Investig 2020;24(6):1877-1888. PubMed

See these in context on the Mastic monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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