Maximum Spectrum Enzym-Complete/DPP-IV Fruit Free w/Isogest Ingredients & Drug Interactions
by Kirkman
What is this page for?
First and foremost: checking Maximum Spectrum Enzym-Complete/DPP-IV Fruit Free w/Isogest against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Maximum Spectrum Enzym-Complete/DPP-IV Fruit Free w/Isogest is a dietary supplement by Kirkman with 16 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Maximum Spectrum Enzym-Complete/DPP-IV Fruit Free w/Isogest by Kirkman
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This capsule contains 16 active digestive enzymes. Lipase breaks down fats, lactase helps digest milk sugar (lactose), and the three protease forms break down proteins.
You'll also get amylase and related carbohydrate-digesting enzymes (cellulase, glucoamylase, alpha-galactosidase, xylanase, and diastase), plus peptidase, phytase, and two branded blends: n-zimes and Isogest. The inactive ingredients are vegetable cellulose (the capsule) and water.
Does it work?
Strong evidence
The evidence for most of these enzymes is still being established. Lactase is effective for lactose intolerance — that one's well supported.
For lipase, phytase, and the proteases, the data we hold rates the evidence as insufficient to say whether they work for their intended uses. The product may help with digestion, but the scientific backing isn't solid yet for most of what's in it.
How safe is it?
Well-documented data
These enzymes are generally well tolerated when taken as directed. Lipase, lactase, and the proteases are all considered safe for most adults in supplement form, though a small number of people exposed to airborne protease powder in occupational settings have reported allergic reactions like rhinoconjunctivitis or asthma — a concern mainly for workers, not typical users.
Phytase carries limited human safety data and is considered low-risk in foods, but supplement use hasn't been studied much. For pregnancy: lactase is likely safe, but lipase, phytase, and the proteases all lack enough safety data in pregnancy — talk with your doctor before regular use.
For breastfeeding: there isn't enough data on lipase, phytase, or the proteases, so check with your doctor or pharmacist first. Lactase is probably okay, but confirm with your own healthcare provider.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
This is a broad-spectrum enzyme blend suited to people looking for digestive support, though the evidence is strongest only for lactase. If you have a serious digestive condition, talk it over with your doctor first — especially before pregnancy or while breastfeeding.
Check your exact medications with the tool below, and run the product by your doctor or pharmacist to be sure it fits your health picture.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 6 of 16 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Maximum Spectrum Enzym-Complete/DPP-IV Fruit Free w/Isogest, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Maximum Spectrum Enzym-Complete/DPP-IV Fruit Free w/Isogest by Kirkman, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 200 DU | -- |
| Lipase | 15000 FCCLU | -- |
| Lactase | 2000 ALU | -- |
| Cellulase | 200 CU | -- |
| Peptidase | 60000 HUT | -- |
| Invertase | 1000 SU | -- |
| Glucoamylase | 250 AGU | -- |
| Alpha-Galactosidase | 125 GaIU | -- |
| Xylanase | 100 XU | -- |
| Phytase | 10 FTU | -- |
| Diastase | 1080 DP | -- |
| Protease 4.5 | 50000 HUT | -- |
| Protease 3 | 30 SAPU | -- |
| Protease 6 | 10000 HUT | -- |
| n-zimes(R) | 892 mg | -- |
| Isogest(R) | 150 Units | -- |
Other ingredients: Vegetable Cellulose, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
FREE OF: Sucrose, soy, casein, gluten, milk, artificial colorings, artificial flavorings, yeast, gelatin, tree nuts, peanuts or fish.
CASEIN & GLUTEN FREE
Storage
IMPORTANT: STORE IN A COOL DRY PLACE AND TIGHTLY CAPPED.
Brand IP Statement(s)
ISOGEST(R) IS KIRKMAN'S SPECIALTY ENZYME FOR ADDRESSING INSUFFICIENT ISOMALTASE ACTIVITY.
n-zimes(R) IS A REGISTERED TRADEMARK OF THE NATIONAL ENZYME COMPANY.
FDA Statement of Identity
Enzyme Dietary Supplement
Suggested/Recommended/Usage/Directions
SUGGESTED USE: 1 Or 2 capsules with meals or as directed by a physician. Capsules may be pulled apart and the contents mixed with food or beverages. For children, one capsule may be sufficient.
General Statements
Best Used by: March 2013
(503)694-1600
Precautions
CAUTION: DO NOT ALLOW THE POWDER IN THE CAPSULES TO GET INTO THE EYE OR CONTACT THE SKIN.
KEEP OUT OF THE REACH OF CHILDREN
General
8869A-120
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Maximum Spectrum Enzym-Complete/DPP-IV Fruit Free w/Isogest by Kirkman label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Maximum Spectrum Enzym-Complete/DPP-IV Fruit Free w/Isogest by Kirkman
These are the 16 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Amylase
Lipase
No knowninteractions
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy fo...
Lipase monograph & interactionsLactase
No knowninteractions
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can red...
Lactase monograph & interactionsCellulase
Peptidase
Invertase
Glucoamylase
Alpha-Galactosidase
Xylanase
Phytase
No knowninteractions
Phytase is an enzyme that breaks down phytic acid (phytate) found in grains, beans, nuts, and seeds, which can free up minerals like iron, zinc, and c...
Phytase monograph & interactionsDiastase
Protease 4.5
No knowninteractions
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...
Protease 4.5 monograph & interactionsProtease 3
No knowninteractions
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...
Protease 3 monograph & interactionsProtease 6
No knowninteractions
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...
Protease 6 monograph & interactionsN-zimes(R)
Isogest(R)
Other (inactive) ingredients: Vegetable Cellulose, Water. These complete the product’s ingredient list but are not active constituents.
Maximum Spectrum Enzym-Complete/DPP-IV Fruit Free w/Isogest by Kirkman Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Maximum Spectrum Enzym-Complete/DPP-IV Fruit Free w/Isogest. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Maximum Spectrum Enzym-Complete/DPP-IV Fruit Free w/Isogest, from the product label.
Kirkman
See all Kirkman products- Name
- Kirkman
- City
- Lake Oswego
- State
- OR
- ZipCode
- 97035
- Phone Number
- (800) 245-8282
- Web Address
- www.kirkmangroup.com
Maximum Spectrum Enzym-Complete/DPP-IV Fruit Free w/Isogest by Kirkman: Common Questions
Does Maximum Spectrum Enzym-Complete/DPP-IV Fruit Free w/Isogest by Kirkman interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does this product actually help with digestion?
Is it safe to take while pregnant?
Can I use it if I'm breastfeeding?
What does lactase do?
Are there any side effects reported?
Should I avoid this if I have a digestive condition?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Maximum Spectrum Enzym-Complete/DPP-IV Fruit Free w/Isogest is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Maximum Spectrum Enzym-Complete/DPP-IV Fruit Free w/Isogest’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographLactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph → Herb & supplement monographPhytase
Phytase is an enzyme that breaks down phytic acid (phytate) found in grains, beans, nuts, and seeds, which can free up minerals like iron, zinc, and calcium for absorption. It is widely used...
Read the full Phytase monograph → Herb & supplement monographProteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph →Sources & How We Checked
Maximum Spectrum Enzym-Complete/DPP-IV Fruit Free w/Isogest's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Phytase 7 references
- Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
- Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
- van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
- Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
- Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
- Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
- Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC