Interaction check not available yet — this product's ingredients haven't been matched to our database.
Dietary supplement

Maximum Spectrum Enzyme Complete Ingredients & Drug Interactions

by Kirkman

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Maximum Spectrum Enzyme Complete is a dietary supplement by Kirkman with 3 active ingredients.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Maximum Spectrum Enzyme Complete by Kirkman

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 15 active ingredients.
  • “Protein Digestion” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Fat Digestion” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Carbohydrate Digestion” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

Maximum Spectrum Enzyme Complete contains 15 active enzymes that work together to help digest food. Lactase breaks down milk sugar; lipase handles fats; the various proteases break down proteins; and other enzymes like amylase, cellulase, and phytase help digest carbohydrates and plant material.

The product also contains inactive ingredients—hypromellose (a capsule material), water, microcrystalline cellulose, and maltodextrin—that help deliver the enzymes.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: digestive enzyme support.
  • We looked for evidence on: Dyspepsia, Lactose intolerance, Indigestion, Bloating and gas.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

Evidence for these enzymes is limited. Lactase is rated effective for lactose intolerance.

The other ingredients—lipase, phytase, and the proteases—don't have enough reliable evidence yet to say whether they work for their intended purposes. We hold no effectiveness data for amylase, cellulase, peptidase, glucoamylase, alpha-galactosidase, xylanase, diastase, invertase, or isogest.

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactase is generally well tolerated. The lipase in this product is also generally well tolerated, though people with serious digestive conditions should use it only under medical guidance.

The proteases (protease 4.5, 6.0, and acid-stable protease 3.0) are generally well tolerated for most adults but may cause digestive upset or allergic reactions in some people. For pregnancy, lactase is likely safe; however, there isn't enough safety data for phytase or the proteases to recommend them during pregnancy unless your doctor advises otherwise.

For breastfeeding, lactase can be used, but check with your healthcare provider first about lipase, phytase, and the proteases, since data are limited. We don't have pregnancy or breastfeeding safety information on file for amylase, cellulase, peptidase, glucoamylase, alpha-galactosidase, xylanase, diastase, invertase, or isogest.

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 4 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Run your medications through the search tool on this page to be sure.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This is a broad-spectrum digestive enzyme blend, most useful if you have trouble digesting certain foods—especially lactose. It's generally well tolerated, but people with serious digestive conditions should check with their doctor first.

If you're pregnant or breastfeeding, talk with your pharmacist or doctor before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 15 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 21, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Maximum Spectrum Enzyme Complete, straight from the product label.

Brand Kirkman
Barcode (UPC) 812325025077
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD May 21, 2025
DSLD ID 333050
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Maximum Spectrum Enzyme Complete by Kirkman, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
120
UPC/BARCODE
812325025077
IngredientAmount% DV
Amylase0 NP--
Lipase0 NP--
Lactase0 NP--
Cellulase0 NP--
Peptidase0 NP--
Glucoamylase0 NP--
Alpha-Galactosidase0 NP--
Xylanase0 NP--
Phytase0 NP--
Diastase0 NP--
Protease 4.50 NP--
Invertase0 NP--
Protease 6.00 NP--
Protein Digestion0 NP--
Fat Digestion0 NP--
Carbohydrate Digestion0 NP--
Kirkman Proprietary Enzyme Blend375 mg--
Acid-Stable Protease 3.00 NP--
Isogest0 NP--

Other ingredients: Hypromellose, Water, Microcrystalline Cellulose, Maltodextrin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

Important: Store in a cool dry place and tightly capped.

Precautions

Keep out of the reach of children.

Caution: Consult your physician if using in the presence of a peptic ulcer.

Allergen warning: Contains sulphites. Enzymes grown on fermentation media containing wheat and soy (may contain undetectable trace amounts).

Suggested/Recommended/Usage/Directions

This product is best taken with food.

Suggested Use: One capsule with meals or as directed by a physician.

Formulation

Free of: Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat or soy

Hypoallergenic Supports digestion of high protein and fat meals

Gluten-Free Fruit free

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Ultra Tested cGMP Certified Current Good Manufacturing Practices Consistent Quality

FDA Statement of Identity

Dietary Supplement

See for yourself

Maximum Spectrum Enzyme Complete by Kirkman label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Maximum Spectrum Enzyme Complete by Kirkman

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Kirkman Proprietary Enzyme Blend

375 mg per serving
  • › Protein Digestion
  • › Fat Digestion
  • › Carbohydrate Digestion

Other (inactive) ingredients: Hypromellose, Water, Microcrystalline Cellulose, Maltodextrin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Maximum Spectrum Enzyme Complete by Kirkman Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Maximum Spectrum Enzyme Complete. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Maximum Spectrum Enzyme Complete, from the product label.

Kirkman

See all Kirkman products
Name
Kirkman
City
Lake Oswego
State
OR
ZipCode
97035
Phone Number
1.800.245.8282
Web Address
kirkmangroup.com
Pharmacist Counseling Corner

Maximum Spectrum Enzyme Complete by Kirkman: Common Questions

Does Maximum Spectrum Enzyme Complete by Kirkman interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Maximum Spectrum Enzyme Complete. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Maximum Spectrum Enzyme Complete contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help with lactose intolerance?
Lactase, one of the enzymes in this product, is rated effective for lactose intolerance. The other enzymes are meant to help digest fats, proteins, and carbohydrates, though the evidence supporting them is still limited.
Can I take this if I have a sensitive stomach?
The enzymes in this product are generally well tolerated, but they may cause digestive upset or allergic reactions in some people. If you have a serious digestive condition, check with your doctor before starting.
Is this safe during pregnancy?
Lactase is likely safe in pregnancy, but there isn't enough safety data for the other enzymes (especially phytase and the proteases) to recommend them unless your doctor advises it. Talk with your doctor or pharmacist for personalized advice.
Can I take this while breastfeeding?
Lactase can be used, but check with your healthcare provider first about the other enzymes—lipase, phytase, and the proteases—since safety data during breastfeeding are limited.
What does each enzyme do?
Lactase breaks down milk sugar; lipase handles fats; the various proteases break down proteins; and amylase, cellulase, and phytase help digest carbohydrates and plant fiber.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Maximum Spectrum Enzyme Complete is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Maximum Spectrum Enzyme Complete label
Sources

Sources & How We Checked

Maximum Spectrum Enzyme Complete's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Phytase 7 references
  1. Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
  2. Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
  3. van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
  4. Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
  5. Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
  6. Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
  7. Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.

See these in context on the Phytase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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