No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Maximum Strength Biotin 5,000 mcg Ingredients & Drug Interactions

by Nature Made

Softgel Capsule Category: Vitamin
No known interaction
The interaction bottom line No known interaction

Maximum Strength Biotin 5,000 mcg is a dietary supplement by Nature Made with 1 active ingredient. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Maximum Strength Biotin 5,000 mcg by Nature Made

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: biotin, a B vitamin at 5,000 micrograms per softgel. Biotin supports the health of hair, skin, and nails, and is essential for converting food into energy.

The softgel also includes inactive ingredients — soybean oil, gelatin, glycerin, beeswax, water, soy lecithin, and added colors — that serve as the capsule and delivery system.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: support healthy hair skin and nails.
  • We looked for evidence on: Biotin deficiency, Brittle nails, Hair loss, Skin quality.
  • The strongest evidence on file: Biotin is rated "Likely Effective" for Biotin deficiency (Natural Medicines).
  • Also on file: Biotin is rated "Insufficient Reliable Evidence To Rate" for Brittle nails.

Biotin is likely effective for treating biotin deficiency, which is rare but can occur with certain medications or health conditions. For other uses — multiple sclerosis, seborrheic dermatitis (a scaly skin condition), and hair loss (alopecia areata) — the evidence is either insufficient or suggests it may not work.

If you're taking it for hair, skin, or nails and don't have a documented deficiency, talk with your doctor about whether the evidence supports it for your specific situation.

The evidence, ingredient by ingredient Biotin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Biotin is generally well tolerated, even at fairly high doses, because your body excretes excess amounts in your urine. High-dose biotin has rarely caused mild diarrhea; one case report described a possible link to a rare inflammatory condition, though whether biotin was the cause remains unclear.

Because this is a high-dose product (5,000 mcg), check with your doctor before starting it — especially if you're pregnant, breastfeeding, or taking other supplements.

Side effects, ingredient by ingredient Biotin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the biotin in this product. Still, since this is a high-dose supplement, mention it to your own doctor or pharmacist to make sure it won't interfere with anything you're taking or any health conditions you have.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This biotin supplement is useful if you have a documented biotin deficiency — otherwise, the evidence for hair, skin, and nail health isn't strong. It doesn't carry documented medication interactions, but high-dose supplements do warrant a quick conversation with your doctor or pharmacist, especially if you're on other medications or prenatal vitamins.

It's generally well tolerated, but it's smart to confirm it's right for you before you begin.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 31, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Maximum Strength Biotin 5,000 mcg, straight from the product label.

Brand Nature Made
Barcode (UPC) 031604040635
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Aug 31, 2018
DSLD ID 180191
Product type Vitamin
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Maximum Strength Biotin 5,000 mcg by Nature Made, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
031604040635
IngredientAmount% DV
Biotin5000 mcg1667%

Other ingredients: Soybean Oil, Gelatin, Glycerin, yellow Beeswax, Water, Soy Lecithin, Colors added

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Everyday value #1 pharmacist recommended

Maximum strength for adults diagnosed with very low levels of biotin

Strength levels of Biotin R Regular 300 mcg or below E Extra above 300 mcg up to 2,500 mcg M Maximum above 2,500 mcg up to 5,000 mcg Helps restore healthy levels of biotin in adults with very low levels, as diagnosed by their health care professional using appropriate biomarkers.

For those with biotin deficiency. USP has tested and verified ingredients, potency, and manufacturing process. USP sets official standards for dietary supplements. www.uspverified.org. Based on Pharmacy Times Survey of pharmacists recommending Letter Vitamin Supplements.

General

List No. 4063 L200 Cat. A611 5A044

Seals/Symbols

USP Dietary Supplement Verified

Formula

Maximum Strength Biotin 5000 mcg

Nature Made Maximum Strength Biotin provides 5000 mcg of biotin, a B vitamin that supports carbohydrate, protein and fat metabolism. Biotin may also help support healthy hair, skin and nails for those that are biotin deficient.

Contains: Soy.

FDA Statement of Identity

Dietary Supplement

Formulation

Colors derived from natural sources - No synthetic dyes No artificial flavors No preservatives No yeast or starch Gluten free

Suggested/Recommended/Usage/Directions

Suggested use: Consult your health care professional before use. Take one softgel daily, with a meal. For easier swallowing, take with water before and during ingestion.

Precautions

Caution: Do not exceed one softgel daily unless recommended by a health care professional.

Store in a cool, dry place, out of reach of children.

Do not use if imprinted seal under cap is broken or missing.

Contains: Soy.

Storage

Keep bottle tightly closed. Store in a cool, dry place, out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Maximum Strength Biotin 5,000 mcg by Nature Made label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Maximum Strength Biotin 5,000 mcg by Nature Made

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Biotin

No known
interactions
5000 mcg per serving Form: Vitamin B7

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Biotin monograph & interactions

Other (inactive) ingredients: Soybean Oil, Gelatin, Glycerin, Yellow Beeswax, Water, Soy Lecithin, Colors added. These complete the product’s ingredient list but are not active constituents.

Interaction report

Maximum Strength Biotin 5,000 mcg by Nature Made Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Maximum Strength Biotin 5,000 mcg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Maximum Strength Biotin 5,000 mcg, from the product label.

Nature Made

See all Nature Made products
Name
Nature Made Nutritional Products
City
Mission Hills
State
CA
ZipCode
91346-9606
Phone Number
1-800-276-2878
Web Address
www.NatureMade.com
Pharmacist Counseling Corner

Maximum Strength Biotin 5,000 mcg by Nature Made: Common Questions

Does Maximum Strength Biotin 5,000 mcg by Nature Made interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Maximum Strength Biotin 5,000 mcg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Maximum Strength Biotin 5,000 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will biotin help my hair, skin, or nails grow?
The evidence is mixed. Biotin is likely effective only if you have a documented deficiency — which is uncommon. For general hair and nail health without a deficiency, the evidence is insufficient or suggests it may not work. If that's why you're considering it, ask your doctor whether it makes sense for your situation.
Is this safe to take while I'm pregnant or breastfeeding?
Biotin is rated likely safe during pregnancy and lactation. That said, this is a high-dose product, and the safety notes recommend checking with your doctor before taking high-dose supplements — especially when you're pregnant or nursing. Talk with your doctor before you start.
What are the side effects?
Biotin is generally well tolerated. Rarely, high-dose biotin has caused mild diarrhea. There's one unusual case report of a possible inflammatory reaction, though it's unclear whether biotin was actually responsible. Serious side effects are uncommon.
Can I take this with my other vitamins or supplements?
No documented interactions are on file for biotin itself. That said, check with your pharmacist or doctor to confirm it won't interfere with your specific medications or supplements, especially since this is a high-dose product.
What if I'm deficient in biotin — how do I know?
Biotin deficiency is rare and usually occurs with certain medications or rare genetic conditions. Your doctor can test for it if they suspect a deficiency. Amounts from food and standard prenatal vitamins are appropriate; high-dose supplements like this one should be discussed with your doctor first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Maximum Strength Biotin 5,000 mcg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Maximum Strength Biotin 5,000 mcg label
Go deeper

The Full Monographs Behind Maximum Strength Biotin 5,000 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Maximum Strength Biotin 5,000 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring