Methihills Ingredients & Drug Interactions
by Herbal Hills
What is this page for?
First and foremost: checking Methihills against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Methihills is a dietary supplement by Herbal Hills with 2 active ingredients. Its ingredients are commonly taken for blood sugar control, boosting breast milk supply, high cholesterol.Based on those ingredients, 389 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Fenugreek seed extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Methihills by Herbal Hills
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HelloPharmacist Scorecard of Methihills by Herbal Hills
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Methihills has two active ingredients: fenugreek seed extract and fenugreek seed powder. The product also contains inactive ingredients—magnesium stearate, silica, and a gelatin capsule—which serve as a binder, anti-caking agent, and capsule material.
Does it work?
Moderate evidence
The data shows fenugreek is possibly effective for sexual dysfunction, sexual arousal, irregular or painful periods (dysmenorrhea), and type 2 diabetes. That means there's some clinical support, but the evidence isn't conclusive.
If you're using this for one of those reasons, talk with your doctor or pharmacist about whether it's a good fit for you and what else might help.
How safe is it?
Well-documented data
Fenugreek is generally well tolerated when eaten in food amounts, but supplement doses may cause side effects and aren't right for everyone. The most common side effects are abdominal pain, bloating, diarrhea, indigestion, gas, low blood sugar (hypoglycemia), and nausea.
Rarely, severe allergic reactions—including facial swelling, throat tightness, wheezing, and shock—can occur. Avoid medicinal use of fenugreek during pregnancy; supplement amounts may affect the uterus.
If you're breastfeeding and considering fenugreek to boost milk supply, the evidence is limited—talk with your provider first. There's no data on file about its safety during pregnancy and lactation specifically, so a conversation with your doctor or pharmacist is important.
Meds to double-check
Moderate interaction found
Check with your pharmacist right away if you take blood thinners (like warfarin or other anticoagulants), antiplatelet drugs (like clopidogrel or aspirin), diabetes medications, theophylline for breathing, metoprolol for blood pressure or heart rate, phenytoin for seizures, or sildenafil for erectile dysfunction. All of these have documented Moderate severity interactions with fenugreek.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Methihills is worth considering if you're interested in fenugreek for sexual health, period pain, or blood sugar support—and if none of your medications interact with it. If you take a blood thinner, diabetes drug, heart medication, seizure medication, breathing medication, or erectile dysfunction medication, you need to check with your pharmacist before starting this.
The interaction risk is real, and your doses may need adjusting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Methihills, straight from the product label.
| Brand | Herbal Hills |
|---|---|
| Barcode (UPC) | 8906008264715 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jan 25, 2013 |
| DSLD ID | 16411 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Methihills by Herbal Hills, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Fenugreek seed extract | 0 NP | -- |
| Fenugreek seed powder | 0 NP | -- |
| {Fenugreek} Blend | 500 mg | -- |
Other ingredients: Magnesium Stearate, Silica, Gelatin Capsule
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
HERBAL HILLS(R) Back to Nature
Methihills(TM)
Seals/Symbols
GMP Good Manufacturing Practice
HERBALHILLS
ISO 22000:2005 CERTIFIED COMPANY
EXTRACT STANDARDIZED EXTRACT
Precautions
Caution: Pregnant or lactating women are advised to consume herbal products under the advice of the Healthcare Practitioner.
FDA Disclaimer Statement
This product is not intended to diagnose, treat, cure or prevent any disease.
General Statements
Not intended for sale of individual units. Multipiece package
Kit Content
Herbal Formulation with Herbal Dietary Supplement for Speedy, Effective & Complete Result
Joint Health Support
Suggested/Recommended/Usage/Directions
Take 1 each of Shatavarihills capsule & Methihills capsule twice daily preferably after meals or as recommended by the Healthcare Practitioner. For better results it should be taken with warm water.
Formula
8% Saponins, 5% Bitter
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Methihills by Herbal Hills label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Methihills by Herbal Hills
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
{Fenugreek} Blend
Other (inactive) ingredients: Magnesium Stearate, Silica, Gelatin Capsule. These complete the product’s ingredient list but are not active constituents.
Methihills by Herbal Hills Drug Interactions
HelloPharmacist Interaction Report
Methihills by Herbal Hills contains fenugreek, which interacts with a number of medications.
The most serious documented concern is with blood thinners (anticoagulants) and clot-prevention drugs (antiplatelet agents)—fenugreek may add to their effects, potentially increasing bleeding risk. This is a Moderate severity interaction.
Read the full breakdown — every affected drug type, severity by severity
Fenugreek also interacts with diabetes medications at Moderate severity; it can lower blood sugar on its own, so taking it alongside diabetes drugs might cause your blood sugar to drop too far. Additionally, it may reduce how well your body absorbs or activates theophylline (a breathing medication), warfarin (Coumadin, a blood thinner), clopidogrel (Plavix, an antiplatelet drug), metoprolol (Toprol, a blood pressure and heart medication), phenytoin (Dilantin, a seizure medication), and sildenafil (Viagra).
All of these are Moderate severity interactions.
Although fenugreek is the only active ingredient here, both forms—the seed extract and the seed powder—carry the same interaction profile. Altogether, these interactions span 386 individual medications.
Use the medication checker below to look up your exact drugs before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Methihills?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Methihills interact with 389 drugs. Click any drug to see the details.
1 of the 2 ingredients in Methihills interact with drugs. Each result below shows which ingredient is responsible. Fenugreek seed extract
Aspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
How Aspirin, Caffeine, Codeine Phosphate interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
How Aspirin, Caffeine, Dihydrocodeine Bitartrate interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, Dover's PwdAcedoval, Dovacet
How Aspirin, Caffeine, Dover's Pwd interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Caffeine, Dover's Pwd interactionAspirin, Caffeine, HydrocodoneDamason-P
How Aspirin, Caffeine, Hydrocodone interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Caffeine, Hydrocodone interactionAspirin, Caffeine, Isobutylallylbarbituric Acid, PhenacetinLanorinal
How Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interactionAspirin, Caffeine, OrphenadrineInvagesic, Invagesic Forte, Norgesic, Norgesic Forte, Orphengesic, Orphengesic Forte
How Aspirin, Caffeine, Orphenadrine interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Caffeine, Orphenadrine interactionAspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
How Aspirin, Caffeine, Phenacetin, Propoxyphene interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionAspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium OxideBufferin
How Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interactionAspirin, CarisoprodolSoma Compound
How Aspirin, Carisoprodol interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Carisoprodol interactionAspirin, Carisoprodol, Codeine PhosphateSoma Compound w/ Codeine
How Aspirin, Carisoprodol, Codeine Phosphate interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Carisoprodol, Codeine Phosphate interactionAspirin, Chlorpheniramine, PhenylpropanolamineAlka-Seltzer Plus Cold
How Aspirin, Chlorpheniramine, Phenylpropanolamine interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionAspirin, Citric Acid, Sodium BicarbonateAlka-Seltzer Pain Reliever and Antacid
How Aspirin, Citric Acid, Sodium Bicarbonate interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Citric Acid, Sodium Bicarbonate interactionAspirin, Codeine PhosphateAspirin w/ Codeine
How Aspirin, Codeine Phosphate interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Codeine Phosphate interactionAspirin, Codeine Phosphate, MethocarbamolRobaxisal C
How Aspirin, Codeine Phosphate, Methocarbamol interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Codeine Phosphate, Methocarbamol interactionAspirin, Codeine Phosphate, PhenobarbitalPhenaphen
How Aspirin, Codeine Phosphate, Phenobarbital interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Codeine Phosphate, Phenobarbital interactionAspirin, Diphenhydramine, PhenylpropanolamineAlka Seltzer Plus Night Time Effervescent
How Aspirin, Diphenhydramine, Phenylpropanolamine interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Diphenhydramine, Phenylpropanolamine interactionAspirin, DipyridamoleAggrenox, Asasantin Retard
How Aspirin, Dipyridamole interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Dipyridamole interactionAspirin, Ethoheptazine, MeprobamateEquagesic
How Aspirin, Ethoheptazine, Meprobamate interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Ethoheptazine, Meprobamate interactionAspirin, HydrocodoneAlor 5 500, Lortab ASA
How Aspirin, Hydrocodone interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Hydrocodone interactionAspirin, MeprobamateMicrainin
How Aspirin, Meprobamate interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Meprobamate interactionAspirin, MethocarbamolRobaxisal
How Aspirin, Methocarbamol interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Methocarbamol interactionAspirin, OmeprazoleYosprala
How Aspirin, Omeprazole interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Omeprazole interactionAspirin, OxycodonePercodan
How Aspirin, Oxycodone interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Oxycodone interactionAspirin, PentazocineTalwin Compound
How Aspirin, Pentazocine interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Aspirin, Pentazocine interactionBetrixabanBevyxxa
How Betrixaban interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Betrixaban interactionBivalirudinAngiomax, Angiomax Rtu, Angiox
How Bivalirudin interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Bivalirudin interactionBromfenac SodiumBromsite, Prolensa
How Bromfenac Sodium interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Bromfenac Sodium interactionCabliviCablivi
How Cablivi interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Seed Powder + Cablivi interactionCanagliflozinInvokana
How Canagliflozin interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Powder + Canagliflozin interactionCanagliflozin, MetforminInvokamet
How Canagliflozin, Metformin interacts with Methihills — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Seed PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Seed Powder + Canagliflozin, Metformin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Methihills with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Fenugreek seed extract
Anticoagulant/Antiplatelet Drugs
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Some of the constituents in fenugreek have antiplatelet effects in animal and in vitro research. However, common fenugreek products might not contain sufficient concentrations of these constituents for clinical effects. A clinical study in patients with coronary artery disease or diabetes shows that taking fenugreek seed powder 2.5 grams twice daily for 3 months does not affect platelet aggregation, fibrinolytic activity, or fibrinogen levels .
Antidiabetes Drugs
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Clinical research shows that fenugreek seed can reduce fasting blood glucose and 2-hour postprandial glucose levels in adults with type 2 diabetes.
Clopidogrel (Plavix)
Theoretically, fenugreek seed might alter the clinical effects of clopidogrel by inhibiting its conversion to the active form.
Animal research shows that fenugreek seed 200 mg/kg daily for 14 days increases the maximum serum concentration of clopidogrel by 21%. It is unclear how this affects the pharmacokinetics of the active metabolite of clopidogrel; however, this study found that concomitant use of fenugreek seed and clopidogrel prolonged bleeding time by an additional 11%.
Metoprolol (Toprol)
Theoretically, fenugreek seed might have additive hypotensive effects when used with metoprolol.
Animal research shows that fenugreek seed 300 mg/kg daily for 2 weeks decreases systolic and diastolic blood pressure by 9% and 11%, respectively, when administered alone, and by 15% and 22%, respectively, when given with metoprolol 10 mg/kg.
Phenytoin (Dilantin)
Theoretically, fenugreek might decrease plasma levels of phenytoin.
Animal research shows that taking fenugreek seeds for 1 week decreases maximum concentrations and the area under the curve of a single dose of phenytoin by 44% and 72%, respectively. This seems to be related to increased clearance. So far, this interaction has not been reported in humans.
Sildenafil (Viagra)
Theoretically, concurrent use of sildenafil and fenugreek might reduce levels and therapeutic effects of sildenafil.
Animal research shows that taking fenugreek seeds for 1 week reduces maximum concentrations and the area under the curve of a single dose of sildenafil by 27% and 48%, respectively. So far, this interaction has not been reported in humans.
Theophylline
Theoretically, fenugreek may reduce the levels and clinical effects of theophylline.
Animal research shows that fenugreek 50 grams daily for 7 days reduces the maximum serum concentration (Cmax) of theophylline by 28% and the area under the plasma drug concentration-time curve (AUC) by 22%.
Warfarin (Coumadin)
Theoretically, fenugreek might have additive effects with warfarin and increase the international normalized ratio (INR).
Some fenugreek constituents have antiplatelet effects, although these might not be present in concentrations that are clinically significant. In one case report, a patient taking warfarin experienced an increased INR when starting to take fenugreek in combination with boldo.
Antihypertensive Drugs
Fenugreek may also have an additive effect on blood pressure-lowering medications. Studies on animals have shown that fenugreek seed can decrease both systolic and diastolic blood pressure by up to 22% when combined with metoprolol. Therefore, it is essential to monitor your blood pressure regularly if you are taking fenugreek and metoprolol together or any other antihypertensive drugs.
Brand information
Manufacturer and brand details for Methihills, from the product label.
Herbal Hills
See all Herbal Hills products- Name
- Isha Agro Developers Pvt. Ltd.
- Street Address
- 55-A/B, Lonavala Indl. Co-op. Est. Ltd.
- City
- Nangargaon
- State
- Lonavala
- Phone Number
- 0091 22 2868 6868
- Web Address
- www.herbalhills.in
Methihills by Herbal Hills: Common Questions
Does Methihills by Herbal Hills interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does fenugreek actually do?
What side effects might I get?
Can I use this while I'm pregnant or breastfeeding?
Will this interact with my blood sugar medication?
Is this safe to take with blood thinners?
Does this product have any fillers?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Methihills is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Methihills’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Methihills's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 30 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Fenugreek 30 references
- Madar Z, Thorne R. Dietary fiber. Prog Food Nutr Sci 1987;11:153-74.
- Sharma RD, Raghuram TC, Rao NS. Effect of fenugreek seeds on blood glucose and serum lipids in type I diabetes. Eur J Clin Nutr 1990;44:301-6.
- Patil SP, Niphadkar PV, Bapat MM. Allergy to fenugreek (Trigonella foenum graecum). Ann Allergy Asthma Immunol 1997;78:297-300. PubMed
- Lambert J, Cormier J. Potential interaction between warfarin and boldo-fenugreek. Pharmacotherapy 2001;21:509-12. PubMed
- Bordia A, Verma SK, Srivastava KC. Effect of ginger (Zingiber officinale Rosc.) and fenugreek (Trigonella foenumgraecum L.) on blood lipids, blood sugar and platelet aggregation in patients with coronary artery disease. Prostaglandins Leukot Essent Fatty PubMed
- Yalcin SS, Tekinalp G, Ozalp I. Peculiar odor of traditional food and maple syrup urine disease. Pediatr Int 1999;41:108-9. PubMed
- Sewell AC, Mosandl A, Bohles H. False diagnosis of maple syrup urine disease owing to ingestion of herbal tea. N Engl J Med 1999;341:769.. PubMed
- Abdo MS, al-Kafawi AA. Experimental studies on the effect of Trigonella foenum-graecum (abstract). Planta Med 1969;17:14-8.
- Gupta A, Gupta R, Lal B. Effect of Trigonella foenum-graecum (fenugreek) seeds on glycaemic control and insulin resistance in type 2 diabetes mellitus: a double blind placebo controlled study. J Assoc Physicians India 2001;49:1057-61.
- Gabay MP. Galactogogues: medications that induce lactation. J Hum Lact 2002;18:274-9. PubMed
- Chevassus H, Gaillard JB, Farret A, et al. A fenugreek seed extract selectively reduces spontaneous fat intake in overweight subjects. Eur J Clin Pharmacol 2010;66(5):449-55. PubMed
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