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Dietary supplement

MK-7 150 mcg Ingredients & Drug Interactions

by Healthy Directions

MK-7 150 mcg label
See full label image
Softgel Capsule Category: Vitamin
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking MK-7 150 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

MK-7 150 mcg is a dietary supplement by Healthy Directions with 1 active ingredient. Its ingredients are commonly taken for supporting normal blood clotting, bone health, heart and vascular health.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are MenaQ7 Menaquinone-7. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against MK-7 150 mcg by Healthy Directions

Ask about any prescription or over-the-counter medication and we check it for interactions with MK-7 150 mcg by Healthy Directions — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of MK-7 150 mcg by Healthy Directions

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: menaquinone-7 (marketed as MenaQ7), a form of vitamin K. The remaining ingredients — medium chain triglycerides, gelatin, glycerin, olive oil, and purified water — are inactive ingredients that form the softgel capsule and help deliver the vitamin K.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: bone and heart health support.
  • We looked for evidence on: Osteoporosis, Cardiovascular disease (CVD), Stroke, Warfarin anticoagulation, Bone mineral density, Arterial calcification — and 1 related terms.
  • The strongest evidence on file: Vitamin K is rated "Effective" for Warfarin anticoagulation (Natural Medicines).
  • Also on file: Vitamin K is rated "Possibly Effective" for Osteoporosis.
  • Also on file: Vitamin K is rated "Insufficient Reliable Evidence To Rate" for Cardiovascular disease (CVD), Stroke.

Vitamin K is effective for treating bleeding disorders caused by vitamin K deficiency and low clotting factors, and it's also effective for reversing warfarin anticoagulation when medically necessary. The evidence also suggests it may be possibly effective for osteoporosis, though the data here is not as strong.

If you're considering this supplement for bone health, talk it over with your doctor about whether the evidence supports it for your situation.

The evidence, ingredient by ingredient Vitamin K

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taken by mouth, vitamin K is generally well tolerated in healthy people. The most common side effects are mild — nausea, diarrhea, and stomach upset — and they're not the norm.

The safety notes advise checking with your doctor before using supplements, even though dietary amounts are fine. Vitamin K is likely safe in pregnancy and while breastfeeding, so that's one less concern if you're in either situation.

Side effects, ingredient by ingredient Vitamin K

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin K.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take warfarin (Coumadin) or any warfarin-based blood thinner, this is a major interaction — vitamin K will reduce how well warfarin works. Check with your doctor before starting this supplement.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This supplement is a straightforward source of vitamin K in a single-ingredient softgel. It's generally well tolerated and effective for vitamin K deficiency and clotting disorders.

The critical catch: if you take warfarin or another blood thinner, you must talk with your doctor before starting — the interaction is major and could compromise your treatment. Otherwise, check your exact medications with the search tool on this page before you begin.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 31, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about MK-7 150 mcg, straight from the product label.

Brand Healthy Directions
Barcode (UPC) 678829292236
Net contents 30 Softgel(s)
Market status On market
Date entered into DSLD Aug 31, 2018
DSLD ID 179502
Product type Vitamin
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for MK-7 150 mcg by Healthy Directions, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
30
UPC/BARCODE
678829292236
IngredientAmount% DV
MenaQ7 Menaquinone-7150 mcg--

Other ingredients: Medium Chain Triglycerides, Gelatin, Glycerin, Olive Oil, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

MK-7 is menaquinone-7, also known as vitamin K2.

Unconditionally guaranteed for purity and labeled potency.

Clinical Grade

For bone and heart health support Aids in calcium absorption

Please see bottom of bottle for Lot No. and Expiration Date

Almost Out? Call 1-866-599-9491 Choose AutoDelivery, Get Free Shipping Forever

Storage

Store bottle in a cool, dry place.

Brand IP Statement(s)

MenaQ7 is a registered trademark of NattoPharma ASA, Norway; Patented in the United States and Canada. US Patent Numbers 8,728,553 & 8,354,129; Canada Patent Number 2,347,387

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

MK-7 150 mcg per serving

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 softgel daily.

Precautions

Warning: If you take warfarin or other blood thinning products, or are pregnant or lactating, consult a health care professional before taking this product.

Keep out of reach of children.

Seals/Symbols

GF Gluten Free

Formulation

GF Gluten Free

General

SKU: HMK 02 G13000, 2017 R-1

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

MK-7 150 mcg by Healthy Directions label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

MK-7 150 mcg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in MK-7 150 mcg by Healthy Directions

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

MenaQ7 Menaquinone-7

Interacts with
2 drugs
150 mcg per serving Form: Vitamin K2

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but suppl...

MenaQ7 Menaquinone-7 monograph & interactions

Other (inactive) ingredients: Medium Chain Triglycerides, Gelatin, Glycerin, Olive Oil, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

MK-7 150 mcg by Healthy Directions Drug Interactions

Want to check YOUR meds against MK-7 150 mcg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2Drugs
2 Major

Ingredients driving the most interactions

MenaQ7 Menaquinone-7 2

Individual Drug Interactions

The ingredients in MK-7 150 mcg interact with 2 drugs. Click any drug to see the details.

1 of the 1 ingredient in MK-7 150 mcg interact with drugs. Each result below shows which ingredient is responsible. MenaQ7 Menaquinone-7

Each ingredient & the kinds of drugs it affects

For each ingredient in MK-7 150 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

MenaQ7 Menaquinone-71 drug type · 2 drugs

Warfarin (Coumadin)

Vitamin K can antagonize and reverse the therapeutic effects of warfarin.
Vitamin K antagonizes the effects of warfarin. Excessive vitamin K intake, either from supplements or from changes in the diet, can reduce the anticoagulant effect of warfarin.

Likelihood Likely Evidence C
MenaQ7 Menaquinone-7 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for MK-7 150 mcg, from the product label.

Healthy Directions

See all Healthy Directions products
Name
Healthy Directions
City
Bethesda
State
MD
ZipCode
20817
Web Address
healthydirections.com
Pharmacist Counseling Corner

MK-7 150 mcg by Healthy Directions: Common Questions

Does MK-7 150 mcg by Healthy Directions interact with any medications?
Yes. Based on its ingredients, MK-7 150 mcg has a known interaction with 2 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
MK-7 150 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is menaquinone-7, and why is it in this product?
Menaquinone-7 (marketed as MenaQ7) is a form of vitamin K. It's included because vitamin K is effective at treating deficiency and supporting normal blood clotting and, possibly, bone health.
Can I take this if I'm on warfarin?
No — not without your doctor's approval. Vitamin K directly opposes warfarin's blood-thinning effect and can make warfarin less effective. You must talk with your doctor or pharmacist before starting.
What are the side effects?
Taken by mouth, vitamin K is generally well tolerated. The most common side effects are mild: nausea, diarrhea, and stomach upset. Serious side effects are very rare.
Is this safe during pregnancy or while breastfeeding?
Yes — vitamin K is likely safe in pregnancy and lactation. Still, it's always wise to check with your doctor before starting any supplement when you're pregnant or nursing.
Is this just a filler, or is there actually an active ingredient?
This is a single-ingredient supplement with one active component: menaquinone-7. The other ingredients — olive oil, gelatin, glycerin, and the like — are just the softgel capsule itself.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if MK-7 150 mcg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

MK-7 150 mcg label
Go deeper

The Full Monographs Behind MK-7 150 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin K

Interacts with 2 drugs

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but supplements are sometimes used for deficiency...

Read the full Vitamin K monograph →
Sources

Sources & How We Checked

MK-7 150 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin K 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Crowther MA, Ageno W, Garcia D, et al. Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial. Ann Intern Med. 2009;150(5):293-300. PubMed
  4. Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation? Nutr Rev. 2010;68(3):178-81. PubMed
  5. Kim JS, Nafziger AN, Gaedigk A, et al. Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe. J Clin Pharmacol. 2001 Jul;41(7):715-22. PubMed
  6. Riegert-Johnson, D. L. and Volcheck, G. W. The incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective review. Ann.Allergy Asthma Immunol. 2002;89(4):400-406. PubMed
  7. Dezee, K. J., Shimeall, W. T., Douglas, K. M., Shumway, N. M., and O'malley, P. G. Treatment of excessive anticoagulation with phytonadione (vitamin K): a meta-analysis. Arch.Intern.Med. 2-27-2006;166(4):391-397. DOI
  8. Dentali, F., Ageno, W., and Crowther, M. Treatment of coumarin-associated coagulopathy: a systematic review and proposed treatment algorithms. J.Thromb.Haemost. 2006;4(9):1853-1863. PubMed
  9. Caluwé R, Vandecasteele S, Van Vlem B, Vermeer C, De Vriese AS. Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study. Nephrol Dial Transplant. 2014;29(7):1385-90.
  10. Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, Fan SW. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials. Osteoporos Int. 2015;26(3):1175-86. PubMed
  11. Hunnali CR, Devi U, Kitchanan S, Sethuraman G. Three Different Regimens for Vitamin K Birth Prophylaxis in Infants Born Preterm: A Randomized Clinical Trial. J Pediatr 2023;255:98-104. PubMed

See these in context on the Vitamin K monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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