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Dietary supplement

MK-7 Vitamin K-2 Extra Strength - 300 mcg Ingredients & Drug Interactions

by NOW

MK-7 Vitamin K-2 Extra Strength - 300 mcg label
See full label image
Capsule Category: Vitamin
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking MK-7 Vitamin K-2 Extra Strength - 300 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

MK-7 Vitamin K-2 Extra Strength - 300 mcg is a dietary supplement by NOW with 1 active ingredient. Its ingredients are commonly taken for supporting normal blood clotting, bone health, heart and vascular health.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin K2. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against MK-7 Vitamin K-2 Extra Strength - 300 mcg by NOW

Ask about any prescription or over-the-counter medication and we check it for interactions with MK-7 Vitamin K-2 Extra Strength - 300 mcg by NOW — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of MK-7 Vitamin K-2 Extra Strength - 300 mcg by NOW

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: vitamin K-2, a fat-soluble vitamin your body uses to make clotting factors and support bone health. Each capsule delivers 300 micrograms.

The other ingredients — microcrystalline cellulose, hypromellose, silicon dioxide, and medium-chain triglycerides — are inactive ingredients that help form and deliver the capsule.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: strong healthy bones and blood coagulation.
  • We looked for evidence on: Osteoporosis, Hemorrhagic disease, Hypoprothrombinemia, Vitamin K-dependent clotting factors deficiency (VKCFD), Warfarin anticoagulation, Bone density — and 3 related terms.
  • The strongest evidence on file: Vitamin K is rated "Effective" for Hemorrhagic disease (Natural Medicines).
  • Also on file: Vitamin K is rated "Effective" for Hypoprothrombinemia, Warfarin anticoagulation, Vitamin K-dependent clotting factors deficiency (VKCFD).
  • Also on file: Vitamin K is rated "Possibly Effective" for Osteoporosis.

The evidence supports vitamin K-2 for correcting vitamin K deficiency, including low clotting factors (hypoprothrombinemia and vitamin K-dependent clotting factor deficiency) and hemorrhagic disease. It's also rated effective for managing warfarin dosing when that's medically necessary.

For bone health, the data rates it possibly effective for osteoporosis, meaning there's some promise but the evidence isn't conclusive yet.

The evidence, ingredient by ingredient Vitamin K

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taken by mouth, vitamin K-2 is generally well tolerated in most healthy people at typical doses. The most common side effects are mild: nausea, diarrhea, stomach upset, and abdominal pain.

Because this supplement can interfere with blood thinners, the safety notes advise checking with your doctor before taking supplements — normal dietary amounts are fine, but a concentrated supplement is different. The data on pregnancy and lactation rates vitamin K as likely safe, though as always, discuss any supplement with your obstetrician or midwife during pregnancy.

Side effects, ingredient by ingredient Vitamin K

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin K.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take warfarin (Coumadin) or acenocoumarol, this is a Major interaction — your blood thinner's effectiveness can drop significantly. Talk to your pharmacist before adding this supplement; your doctor may need to adjust your dose or monitor you more closely.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

If you have a vitamin K deficiency or your doctor has prescribed vitamin K, this supplement is supported by evidence. If you take warfarin or another blood thinner, do not use this product without talking to your pharmacist or doctor first — the vitamin K can make your blood thinner less effective.

For anyone else, it's generally well tolerated at this dose.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about MK-7 Vitamin K-2 Extra Strength - 300 mcg, straight from the product label.

Brand NOW
Barcode (UPC) 733739009951
Net contents 120 Veg Capsule(s)
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 335281
Product type Vitamin
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Halal, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for MK-7 Vitamin K-2 Extra Strength - 300 mcg by NOW, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veg Capsule(s)
Maximum serving Sizes:
1 Veg Capsule(s)
Servings per container
120
UPC/BARCODE
733739009951
IngredientAmount% DV
Vitamin K2300 mcg--

Other ingredients: Microcrystalline Cellulose, Hypromellose, Silicon Dioxide, Medium Chain Triglycerides

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested usage: Take 1 capsule daily with a meal.

Formula

Vitamin K is well known for its role in the synthesis of a number of blood coagulation factors and is also important for the formation of strong, healthy bones. MenaQ7 MK-7 is a unique soy-free, bioavailable form of vitamin K2 that plays a critical role in arterial health through its ability to support proper calcium metabolism in blood vessels and arteries.

Crescent H (Halal)

MenaQ7

This extra strength product has three times the vitamin K2 (300 mcg) as in our regular strength product (100 mcg).

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Caution: For adults only.

Consult physician if pregnant/nursing, taking medication (especially anti-coagulant drugs such as warfarin, Coumadin, heparin), or have a medical condition.

Keep out of reach of children.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Formulation

Natural color variation may occur in this product.

Supports bone health Cardiovascular support

Vegetarian/Vegan

Non-GMO

Made and quality tested in the USA with globally sourced ingredients.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or sesame ingredients.

General Statements

This bottle is made from 100% PCR (post-consumer recycled) resin.

Vitamins Family owned since 1968.

Seals/Symbols

Crescent H (Halal) GMP Quality Assured

FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

MenaQ7 is a registered trademark of Lesaffre et Compagnie, France.

Storage

Store in a cool, dry place after opening.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

MK-7 Vitamin K-2 Extra Strength - 300 mcg by NOW label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

MK-7 Vitamin K-2 Extra Strength - 300 mcg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in MK-7 Vitamin K-2 Extra Strength - 300 mcg by NOW

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veg Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Vitamin K2

Interacts with
2 drugs
300 mcg per serving Form: MenaQ7

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but suppl...

Vitamin K2 monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Hypromellose, Silicon Dioxide, Medium Chain Triglycerides. These complete the product’s ingredient list but are not active constituents.

Interaction report

MK-7 Vitamin K-2 Extra Strength - 300 mcg by NOW Drug Interactions

Want to check YOUR meds against MK-7 Vitamin K-2 Extra Strength - 300 mcg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2Drugs
2 Major

Ingredients driving the most interactions

Vitamin K2 2

Individual Drug Interactions

The ingredients in MK-7 Vitamin K-2 Extra Strength - 300 mcg interact with 2 drugs. Click any drug to see the details.

1 of the 1 ingredient in MK-7 Vitamin K-2 Extra Strength - 300 mcg interact with drugs. Each result below shows which ingredient is responsible. Vitamin K2

Each ingredient & the kinds of drugs it affects

For each ingredient in MK-7 Vitamin K-2 Extra Strength - 300 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin K21 drug type · 2 drugs

Warfarin (Coumadin)

Vitamin K can antagonize and reverse the therapeutic effects of warfarin.
Vitamin K antagonizes the effects of warfarin. Excessive vitamin K intake, either from supplements or from changes in the diet, can reduce the anticoagulant effect of warfarin.

Likelihood Likely Evidence C
Vitamin K2 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for MK-7 Vitamin K-2 Extra Strength - 300 mcg, from the product label.

NOW

See all NOW products
Name
NOW Foods
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Web Address
nowfoods.com
Pharmacist Counseling Corner

MK-7 Vitamin K-2 Extra Strength - 300 mcg by NOW: Common Questions

Does MK-7 Vitamin K-2 Extra Strength - 300 mcg by NOW interact with any medications?
Yes. Based on its ingredients, MK-7 Vitamin K-2 Extra Strength - 300 mcg has a known interaction with 2 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
MK-7 Vitamin K-2 Extra Strength - 300 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this hurt my warfarin?
Yes, vitamin K can weaken warfarin's effect. If you take warfarin, do not use this supplement without checking with your pharmacist or doctor first. They may need to adjust your warfarin dose or monitor your blood clotting.
What side effects should I expect?
The most common are mild stomach-related: nausea, diarrhea, upset stomach, and abdominal pain. Most people who take vitamin K by mouth tolerate it well.
Is it safe to take during pregnancy?
The safety data rates vitamin K as likely safe in pregnancy. Still, talk with your obstetrician or pharmacist before starting any supplement during pregnancy or while breastfeeding.
What is vitamin K-2, and why do I need it?
Vitamin K-2 is a fat-soluble vitamin your body uses to make blood clotting factors and support bone strength. Most people get enough from food, but supplements may help if you have a deficiency or if your doctor recommends it for bone health.
Is this product effective for bone health?
The evidence rates vitamin K as possibly effective for osteoporosis, meaning there's some promise but the proof isn't yet conclusive. Ask your doctor whether it might help your specific situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if MK-7 Vitamin K-2 Extra Strength - 300 mcg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

MK-7 Vitamin K-2 Extra Strength - 300 mcg label
Go deeper

The Full Monographs Behind MK-7 Vitamin K-2 Extra Strength - 300 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin K

Interacts with 2 drugs

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but supplements are sometimes used for deficiency...

Read the full Vitamin K monograph →
Sources

Sources & How We Checked

MK-7 Vitamin K-2 Extra Strength - 300 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin K 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Crowther MA, Ageno W, Garcia D, et al. Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial. Ann Intern Med. 2009;150(5):293-300. PubMed
  4. Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation? Nutr Rev. 2010;68(3):178-81. PubMed
  5. Kim JS, Nafziger AN, Gaedigk A, et al. Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe. J Clin Pharmacol. 2001 Jul;41(7):715-22. PubMed
  6. Riegert-Johnson, D. L. and Volcheck, G. W. The incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective review. Ann.Allergy Asthma Immunol. 2002;89(4):400-406. PubMed
  7. Dezee, K. J., Shimeall, W. T., Douglas, K. M., Shumway, N. M., and O'malley, P. G. Treatment of excessive anticoagulation with phytonadione (vitamin K): a meta-analysis. Arch.Intern.Med. 2-27-2006;166(4):391-397. DOI
  8. Dentali, F., Ageno, W., and Crowther, M. Treatment of coumarin-associated coagulopathy: a systematic review and proposed treatment algorithms. J.Thromb.Haemost. 2006;4(9):1853-1863. PubMed
  9. Caluwé R, Vandecasteele S, Van Vlem B, Vermeer C, De Vriese AS. Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study. Nephrol Dial Transplant. 2014;29(7):1385-90.
  10. Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, Fan SW. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials. Osteoporos Int. 2015;26(3):1175-86. PubMed
  11. Hunnali CR, Devi U, Kitchanan S, Sethuraman G. Three Different Regimens for Vitamin K Birth Prophylaxis in Infants Born Preterm: A Randomized Clinical Trial. J Pediatr 2023;255:98-104. PubMed

See these in context on the Vitamin K monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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