No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

MSM Methylsulfonylmethane Ingredients & Drug Interactions

by NutriCology

Capsule Category: Other Combinations
No known interaction
The interaction bottom line No known interaction

MSM Methylsulfonylmethane is a dietary supplement by NutriCology with 2 active ingredients. Its ingredients are commonly taken for correcting molybdenum deficiency, supporting enzyme function, general nutritional supplementation.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of MSM Methylsulfonylmethane by NutriCology

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 2 active ingredients: molybdenum and methylsulfonylmethane (MSM). Molybdenum is a trace mineral your body needs for certain enzyme functions.

We could not check methylsulfonylmethane because we hold no monograph data for it. The capsule also contains inactive ingredients — hydroxypropyl methylcellulose, microcrystalline cellulose, and L-leucine — which are fillers and binders.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: bioavailable form of sulfur.
  • We looked for evidence on: Molybdenum deficiency.
  • The strongest evidence on file: Molybdenum is rated "Likely Effective" for Molybdenum deficiency (Natural Medicines).

Molybdenum is likely effective for treating molybdenum deficiency. For other uses — acne, iron deficiency anemia, asthma, osteoporosis, and esophageal cancer — the evidence is insufficient to know whether molybdenum helps.

We have no effectiveness data on file for methylsulfonylmethane.

The evidence, ingredient by ingredient Molybdenum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Molybdenum is generally well tolerated when you stay within the safe upper limit of 2 mg per day. High-dose supplements can cause problems and are rarely needed.

Dietary amounts and molybdenum in prenatal vitamins are fine, but avoid high-dose supplements unless your doctor tells you to take them. One case report describes severe toxicity (psychosis, seizures, brain damage) from very high doses over a short time, though this is extremely rare.

We have no safety data on file for methylsulfonylmethane.

Side effects, ingredient by ingredient Molybdenum

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That doesn't mean interactions don't exist — it means we haven't found them — so run your exact medications through the checker below or ask your pharmacist before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This product may help if you have a molybdenum deficiency, though that's uncommon. If you're taking it for another reason, the evidence isn't there yet.

Because we couldn't fully check methylsulfonylmethane, and because high-dose molybdenum carries real risks, talk with your pharmacist before starting — especially if you have a stent.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about MSM Methylsulfonylmethane, straight from the product label.

Brand NutriCology
Barcode (UPC) 713947528505
Net contents 150 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2020
DSLD ID 235355
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for MSM Methylsulfonylmethane by NutriCology, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
50
UPC/BARCODE
713947528505
IngredientAmount% DV
Molybdenum30 mcg55%
Methylsulfonylmethane1.5 Gram(s)--

Other ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, L-Leucine

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

MSM is a bioavailable form of sulfur. We include molybdenum because taking supplemental MSM may encourage urinary excretion of molybdenum.

Suggested/Recommended/Usage/Directions

Suggested Use As a dietary supplement, 1 to 3 capsules one to five times daily, or as directed by a healthcare practitioner.

Storage

Keep in a cool, dry place, tightly capped.

Brand IP Statement(s)

OptiMSM is a registered trademark of Bergstrom Nutrition, Inc.

General Statements

NutriCology Innovative Nutrition

Formulation

Hypoallergenic

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

MSM Methylsulfonylmethane by NutriCology label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in MSM Methylsulfonylmethane by NutriCology

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Molybdenum

No known
interactions
30 mcg per serving Form: Sodium Molybdate

Molybdenum is an essential trace mineral your body needs in tiny amounts to help certain enzymes work. Most people get enough from a normal diet, so s...

Molybdenum monograph & interactions

Methylsulfonylmethane

1.5 Gram(s) per serving

Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, L-Leucine. These complete the product’s ingredient list but are not active constituents.

Interaction report

MSM Methylsulfonylmethane by NutriCology Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in MSM Methylsulfonylmethane. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for MSM Methylsulfonylmethane, from the product label.

NutriCology

See all NutriCology products
Name
NutriCology
City
South Salt Lake
State
UT
ZipCode
84115
Phone Number
800.545.9960
Web Address
www.nutricology.com
Pharmacist Counseling Corner

MSM Methylsulfonylmethane by NutriCology: Common Questions

Does MSM Methylsulfonylmethane by NutriCology interact with any medications?
We do not currently list a known interaction for the mapped ingredients in MSM Methylsulfonylmethane. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
MSM Methylsulfonylmethane contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is molybdenum and what does it do?
Molybdenum is a trace mineral that helps your body run certain enzymes. It's likely effective for treating molybdenum deficiency, which is uncommon. We don't have strong evidence that it helps with acne, anemia, asthma, osteoporosis, or cancer.
Is molybdenum safe at high doses?
No — stay under 2 mg per day. High-dose supplements can cause problems and are rarely necessary. Dietary amounts and molybdenum in prenatal vitamins are generally fine, but avoid high-dose supplements on your own. One case report describes severe toxicity from very high doses, so don't exceed the safe limit unless your doctor advises it.
What about the MSM in this product — what does it do?
We don't have effectiveness data on file for methylsulfonylmethane (MSM). We also couldn't check it for interactions because we hold no monograph for it.
Does this product have fillers?
Yes — it contains hydroxypropyl methylcellulose, microcrystalline cellulose, and L-leucine as inactive ingredients.
Can I take this while pregnant or breastfeeding?
For molybdenum, dietary amounts and prenatal vitamins are generally fine, but avoid high-dose supplements without medical advice. We have no pregnancy or breastfeeding data for methylsulfonylmethane. Talk with your doctor or pharmacist before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if MSM Methylsulfonylmethane is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

MSM Methylsulfonylmethane label
Go deeper

The Full Monographs Behind MSM Methylsulfonylmethane’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

MSM Methylsulfonylmethane's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Molybdenum 8 references
  1. Chan S, Gerson B, Subramaniam S. The role of copper, molybdenum, selenium, and zinc in nutrition and health. Clin Lab Med 1998;18:673-85. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Rajagopalan KV. Molybdenum: an essential trace element in human nutrition. Annu Rev Nutr 1988;8:401-27. PubMed
  4. Selden AI, Berg NP, Soderbergh A, Bergstrom BE. Occupational molybdenum exposure and a gouty electrician. Occup Med (Lond) 2005;55:145-8. PubMed
  5. Al-Saleh E, Nandakumaran M, Al-Shammari M, Al-Harouny A. Maternal-fetal status of copper, iron, molybdenum, selenium and zinc in patients with gestational diabetes. J Matern Fetal Neonatal Med 2004;16:15-21. PubMed
  6. Koster R, Vieluf D, Kiehn M, et al. Nickel and molybdenum contact allergies in patients with coronary in-stent restenosis. Lancet 2000;356:1895-7. PubMed
  7. Vyskocil A, Viau C. Assessment of molybdenum toxicity in humans. J Appl Toxicol 1999;19:185-92. DOI
  8. Momcilovic, B. A case report of acute human molybdenum toxicity from a dietary molybdenum supplement--a new member of the "Lucor metallicum" family. Arh.Hig.Rada Toksikol. 1999;50(3):289-297. DOI

See these in context on the Molybdenum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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