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Dietary supplement

Mullein Leaf 2,000 mg Ingredients & Drug Interactions

by Nature's Answer

Mullein Leaf 2,000 mg label
See full label image
Liquid Category: Botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Mullein Leaf 2,000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Mullein Leaf 2,000 mg is a dietary supplement by Nature's Answer with 1 active ingredient. Its ingredients are commonly taken for cough and chest congestion, sore throat, bronchitis and respiratory irritation.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Mullein Leaf Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Mullein Leaf 2,000 mg by Nature's Answer

Ask about any prescription or over-the-counter medication and we check it for interactions with Mullein Leaf 2,000 mg by Nature's Answer — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Mullein Leaf 2,000 mg by Nature's Answer

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product is a liquid extract of mullein leaf at 2,000 mg per serving. Mullein is a plant traditionally used for respiratory complaints, and here it comes as a concentrated extract made with water, glycerin, and alcohol as the inactive ingredients that carry and preserve it.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Mullein's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: respiratory health and cough support.
  • We looked for evidence on: Asthma, Bronchitis, Cough, Influenza, Pneumonia, chest congestion — and 2 related terms.
  • The closest evidence on file: Mullein is rated "Insufficient Reliable Evidence To Rate" for Bronchitis (Natural Medicines).
  • Also on file: Mullein is rated "Insufficient Reliable Evidence To Rate" for Asthma, Cough, Influenza, Pneumonia.

The evidence we have doesn't yet establish that mullein leaf works for cough, bronchitis, asthma, migraine headache, or diarrhea. The data shows insufficient reliable evidence to rate it for any of these uses.

That doesn't mean it doesn't help — it means well-designed human trials haven't settled the question yet.

The evidence, ingredient by ingredient Mullein

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Mullein leaf extract is generally well tolerated when you use it short-term, but human safety data are limited, so we don't have a full picture of longer-term use. A small number of case reports have noted skin reactions (dermatitis) from direct contact with the whole plant or from breathing in plant dust — these happened in people with sensitivities, and one person also reacted to other plants.

The safety data advise against using mullein during pregnancy and breastfeeding, since there isn't enough information to know it's safe for either.

Side effects, ingredient by ingredient Mullein

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Mullein.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take anticoagulant or antiplatelet drugs — blood thinners like warfarin, clopidogrel, aspirin, or similar medicines — double-check with your doctor or pharmacist before adding this product. Mullein has mild blood-thinning effects that could combine with what you're already taking.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

Mullein leaf extract may be worth considering if you're interested in traditional respiratory support and you don't take blood thinners. If you do take anticoagulants or antiplatelet drugs, check with your doctor or pharmacist first — the mild blood-thinning effect could add up.

Steer clear during pregnancy or while breastfeeding. Talk it over with your doctor or pharmacist before you start to make sure it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 19, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Mullein Leaf 2,000 mg, straight from the product label.

Brand Nature's Answer
Barcode (UPC) 083000004124
Net contents 1 fl. Oz.; 30 mL
Market status On market
Date entered into DSLD May 19, 2022
DSLD ID 264085
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Kosher, Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Mullein Leaf 2,000 mg by Nature's Answer, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 mL
Maximum serving Sizes:
2 mL
Servings per container
15
UPC/BARCODE
083000004124
IngredientAmount% DV
Mullein Leaf Extract2000 mg--

Other ingredients: Water, Purified, Glycerin, Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Gluten Free

Bio-Chelated Cold Extraction Process

Lowest 12-15% Organic Alcohol 12-15% by volume Certified Organic Alcohol

Our alcohol extracts are produced using our cold Bio-Chelated proprietary extraction process, yielding a Holistically Balanced Advanced Botanical Fingerprint extract in the same synergistic ratios as in the plant.

Seals/Symbols

K Parve (Kosher)

Formula

KOF-K (Kosher) Parve

Verbascum thapsus Mullein Leaf 2,000 mg per serving

FDA Statement of Identity

Herbal Supplement

Brand IP Statement(s)

Nature's Answer Since 1972

Discover Nature's Answer

Copyright 2020 Nature's Answer

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 2 mL (92 drops) three (3) times a day, in a small amount of water. Shake well.

Precautions

Keep out of reach of children.

Warning: Do not use if pregnant or nursing.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Mullein Leaf 2,000 mg by Nature's Answer label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Mullein Leaf 2,000 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Mullein Leaf 2,000 mg by Nature's Answer

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 mL Dosage formLiquid Servings per container15 Amounts shown are per serving.

Mullein Leaf Extract

Interacts with
122 drugs
2000 mg per serving

Mullein is a traditional herbal remedy most often used as a tea or syrup to soothe coughs, sore throats, and respiratory irritation. High-quality huma...

Mullein Leaf Extract monograph & interactions

Other (inactive) ingredients: Water, Purified, Glycerin, Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Mullein Leaf 2,000 mg by Nature's Answer Drug Interactions

Want to check YOUR meds against Mullein Leaf 2,000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Minor

Ingredients driving the most interactions

Mullein Leaf Extract 122

Individual Drug Interactions

The ingredients in Mullein Leaf 2,000 mg interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Mullein Leaf 2,000 mg interact with drugs. Each result below shows which ingredient is responsible. Mullein Leaf Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Mullein Leaf 2,000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Mullein Leaf Extract1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot. This is likely due to at least one of the known constituents of muellein, triterpenoid saponins. However, the effects appear to be mild and results have been inconsistent. Extracts from different plant parts have been show to have varying anticoagulant strengths, with water-based ones being more potent than alcohol-based extracts.

Likelihood Unlikely Evidence A
Mullein Leaf Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Mullein Leaf 2,000 mg, from the product label.

Nature's Answer

See all Nature's Answer products
Name
Nature's Answer
Street Address
85 Commerce Drive
City
Hauppauge
State
NY
ZipCode
11788
Phone Number
(800) 439-2324
Web Address
www.naturesanswer.com
Pharmacist Counseling Corner

Mullein Leaf 2,000 mg by Nature's Answer: Common Questions

Does Mullein Leaf 2,000 mg by Nature's Answer interact with any medications?
Yes. Based on its ingredients, Mullein Leaf 2,000 mg has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Mullein Leaf 2,000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant or breastfeeding?
No — the safety data advise against it for both pregnancy and breastfeeding because there isn't enough information to know it's safe. Talk with your doctor or pharmacist about whether mullein is right for you in these situations.
Does mullein leaf work for cough or bronchitis?
The evidence we have doesn't yet establish that it does — the data show insufficient reliable evidence to rate it for either. That said, mullein has a long history of use for respiratory complaints, so it may be worth trying alongside advice from your doctor.
What are the side effects?
Mullein leaf extract is generally well tolerated for short-term use. A small number of case reports noted skin reactions from direct contact with the whole plant or from breathing in plant dust — these happened in people with sensitivities to the plant. Human safety data are limited, so longer-term effects aren't fully known.
What is mullein leaf extract used for?
It's traditionally been used for respiratory complaints like cough, bronchitis, and asthma, though the evidence to confirm it works for these isn't yet reliable enough to rate.
Does this have any other ingredients besides mullein?
No active ingredients besides mullein leaf extract. The liquid also contains water, glycerin, and alcohol — these are inactive ingredients that carry and preserve the extract.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Mullein Leaf 2,000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Mullein Leaf 2,000 mg label
Go deeper

The Full Monographs Behind Mullein Leaf 2,000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Mullein

Interacts with 122 drugs

Mullein is a traditional herbal remedy most often used as a tea or syrup to soothe coughs, sore throats, and respiratory irritation. High-quality human studies are lacking, so its benefits a...

Read the full Mullein monograph →
Sources

Sources & How We Checked

Mullein Leaf 2,000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Mullein 2 references
  1. Castro AI, Carmona JB, Gonzales FG, Nestar OB. Occupational airborne dermatitis from gordolobo (Verbascum densiflorum). Contact Dermatitis 2006;55(5):301.
  2. Flores Echaiz C, Al Ali A, Cao AQ, Sasseville D. Simultaneous contact dermatitis caused by Asteraceae and Verbascum thapsus. Contact Dermatitis 2017;76(5):316-8.

See these in context on the Mullein monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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