Natto-Serrazime Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Natto-Serrazime against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Natto-Serrazime is a dietary supplement by Designs for Health with 2 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Natto-Serrazime by Designs for Health
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product has 2 active ingredients: Nattozimes and Serrazimes, both proteolytic enzymes — proteins that break down other proteins. Proteolytic enzymes are used to support protein digestion and may help with inflammation and circulation.
The product also contains inactive ingredients (rice bran, vegetable cellulose, microcrystalline cellulose, and water) as fillers and capsule material.
Does it work?
Couldn't assess
We hold no effectiveness data in our records for Nattozimes or Serrazimes. The evidence for these ingredients is not established in the data we have on file.
How safe is it?
Well-documented data
Nattozimes is generally well tolerated for most adults, but it may cause digestive upset or allergic reactions in some people. Rarely, people exposed to proteolytic enzymes — either through the air or on the skin — have developed allergic reactions including allergic rhinitis (runny nose and itchy eyes) or asthma; if you notice respiratory symptoms or severe reactions, stop and talk to your doctor.
The safety data advises against use during pregnancy unless your doctor prescribes it. There is little safety data during breastfeeding, so medical advice is needed before use.
We could not check Serrazimes for safety information.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. However, we hold no interaction data for Serrazimes, so check with your doctor or pharmacist if you take any medications and want to be thorough.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Natto-Serrazime is generally well tolerated for most adults looking to support protein digestion. If you're pregnant, breastfeeding, or have a history of allergic reactions to enzymes or detergent products, talk with your doctor or pharmacist before starting.
Run it by your own healthcare provider if you take any medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Natto-Serrazime, straight from the product label.
| Brand | Designs for Health |
|---|---|
| Barcode (UPC) | 879452000506 |
| Net contents | 120 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 25, 2013 |
| DSLD ID | 22481 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Natto-Serrazime by Designs for Health, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Nattozimes(R) | 129 mg | -- |
| Serrazimes(R) | 33 mg | -- |
Other ingredients: Rice Bran, Vegetable Cellulose, Microcrystalline Cellulose, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Notice: Color, size or shape may appear different between lots.
For Professional Use Only
Manufactured in an NSF GMP Registered Facility
Formulation
Does not contain gluten.
General
NTS120-1
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Guaranteed GMP CERTIFIED Products
Suggested/Recommended/Usage/Directions
Recommended Use: As a dietary supplement, take one capsule per day, or as directed by your health care practitioner.
Storage
STORE IN A COOL, DRY PLACE.
Precautions
KEEP OUT OF REACH OF CHILDREN.
Brand IP Statement(s)
Nattozimes(R) and Serrazimes(R) are registered trademarks of National Enzyme Company.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Natto-Serrazime by Designs for Health label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Natto-Serrazime by Designs for Health
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Nattozimes(R)
No knowninteractions
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...
Nattozimes(R) monograph & interactionsSerrazimes(R)
Other (inactive) ingredients: Rice Bran, Vegetable Cellulose, Microcrystalline Cellulose, Water. These complete the product’s ingredient list but are not active constituents.
Natto-Serrazime by Designs for Health Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Natto-Serrazime. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Natto-Serrazime, from the product label.
Designs for Health
See all Designs for Health products- Name
- Designs for Health, Inc.
- Street Address
- 980 South Street
- City
- Suffield
- State
- CT
- ZipCode
- 06078
- Web Address
- www.designsforhealth.com
Natto-Serrazime by Designs for Health: Common Questions
Does Natto-Serrazime by Designs for Health interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this while pregnant?
Is it safe to breastfeed while taking Natto-Serrazime?
Could this cause an allergic reaction?
What are Nattozimes and Serrazimes?
What inactive ingredients are in this product?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Natto-Serrazime is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Natto-Serrazime’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Natto-Serrazime's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC