Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

PharmaGABA Chewables Ingredients & Drug Interactions

by Designs for Health

PharmaGABA Chewables label
See full label image
Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking PharmaGABA Chewables against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

PharmaGABA Chewables is a dietary supplement by Designs for Health with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, sleep problems, relaxation.Based on those ingredients, 419 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are gamma-Aminobutyric acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against PharmaGABA Chewables by Designs for Health

Ask about any prescription or over-the-counter medication and we check it for interactions with PharmaGABA Chewables by Designs for Health — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of PharmaGABA Chewables by Designs for Health

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

PharmaGABA Chewables contains one active ingredient: GABA (gamma-aminobutyric acid), a compound your brain naturally makes to help calm and relax your nervous system. The tablet also contains inactive ingredients—dextrose, magnesium stearate, natural flavors, citric acid, and silica—that help make the chewable form work.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Gamma-aminobutyric Acid (gaba)'s own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Calming neurotransmitter support for relaxation.
  • We looked for evidence on: Anxiety, Stress, Insomnia, Sleep quality, Nervous tension.
  • The closest evidence on file: Gamma-aminobutyric Acid (gaba) is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: Gamma-aminobutyric Acid (gaba) is rated "Insufficient Reliable Evidence To Rate" for Insomnia, Post-traumatic stress disorder (PTSD).

The evidence for GABA chewables isn't established in our data. We have insufficient reliable evidence to rate how well it works for anxiety, ADHD, athletic performance, cerebral palsy, or chronic bronchitis.

If you're thinking about it for one of these reasons, talk with your doctor about what the current research actually supports.

The evidence, ingredient by ingredient Gamma-aminobutyric Acid (gaba)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

GABA is often well tolerated in the short term when taken by mouth, with the most common side effects being drowsiness, nausea, gastric upset, minor throat burning, and muscle weakness. Long-term safety hasn't been well studied.

Because there isn't enough safety data, avoid this product unless your doctor advises otherwise, and don't use it while breastfeeding.

Side effects, ingredient by ingredient Gamma-aminobutyric Acid (gaba)

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Gamma-aminobutyric Acid (gaba).
  • The most serious interaction on file is rated Moderate.
  • For scale: 419 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take blood pressure medications (antihypertensive drugs), check before starting PharmaGABA—it may lower your blood pressure further. Also double-check if you're on any sedating drugs (CNS depressants like sleep aids or anxiety medications), since GABA could add to their drowsy effects.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

PharmaGABA Chewables may be worth considering if your doctor thinks GABA is right for you—especially if you're not on blood pressure medication or sedating drugs. If you take antihypertensive or CNS depressant medications, check with your doctor or pharmacist before starting.

The long-term safety picture isn't clear, so keep that conversation going with your healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about PharmaGABA Chewables, straight from the product label.

Brand Designs for Health
Barcode (UPC) 879452002890
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Jul 25, 2013
DSLD ID 22489
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for PharmaGABA Chewables by Designs for Health, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
30
UPC/BARCODE
879452002890
IngredientAmount% DV
gamma-Aminobutyric acid200 mg--

Other ingredients: Dextrose, Magnesium Stearates, Natural flavors, Citric Acid, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Notice: Color, size or shape may appear different between lots.

For Professional Use Only

Manufactured in an NSF GMP Registered Facility

General

PGAB60-1

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Guaranteed GMP COMPLIANT Products

Suggested/Recommended/Usage/Directions

Recommended Use: As a dietary supplement, chew two tablets per day, or as directed by your health care practitioner.

Brand IP Statement(s)

PharmaGABA(TM) is a trademark of Pharma Foods International Co., Ltd. PharmaGABA(TM) is a proprietary form of GABA, one of the body’s main calming neurotransmitters, manufactured through a natural fermentation process which has been shown to result in a more clinically effective GABA than generic synthetic forms.

Formulation

Does not contain gluten.

Storage

STORE IN A COOL, DRY PLACE.

Precautions

KEEP OUT OF REACH OF CHILDREN.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

PharmaGABA Chewables by Designs for Health label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

PharmaGABA Chewables label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in PharmaGABA Chewables by Designs for Health

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Gamma-Aminobutyric acid

Interacts with
419 drugs
200 mg per serving Form: PharmaGABA(TM)

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep...

Gamma-Aminobutyric acid monograph & interactions

Other (inactive) ingredients: Dextrose, Magnesium Stearates, Natural flavors, Citric Acid, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

PharmaGABA Chewables by Designs for Health Drug Interactions

Want to check YOUR meds against PharmaGABA Chewables?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
419Drugs
172 Moderate 247 Minor

Ingredients driving the most interactions

gamma-Aminobutyric acid 419

Individual Drug Interactions

The ingredients in PharmaGABA Chewables interact with 419 drugs. Click any drug to see the details.

1 of the 1 ingredient in PharmaGABA Chewables interact with drugs. Each result below shows which ingredient is responsible. gamma-Aminobutyric acid

Each ingredient & the kinds of drugs it affects

For each ingredient in PharmaGABA Chewables with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

gamma-Aminobutyric acid2 drug types · 419 drugs

Antihypertensive Drugs

Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Some clinical research shows that GABA can decrease blood pressure in patients with hypertension.

Likelihood Possible Evidence B
Cns Depressants

Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Endogenous GABA has well-established relaxant effects and GABA(A) receptors have an established physiological role in sleep. However, the effects of GABA supplements are unclear, as it is unknown whether exogenous GABA crosses the blood-brain barrier. Although there have been limited reports of drowsiness or tiredness with GABA supplements, these effects have not been widely reported in clinical studies. Additionally, intravenous GABA 0.1-1 mg/kg has been shown to induce anxiety in a dose-dependent manner.

Likelihood Unlikely Evidence D
gamma-Aminobutyric acid full monograph & interactions
The maker

Brand information

Manufacturer and brand details for PharmaGABA Chewables, from the product label.

Designs for Health

See all Designs for Health products
Name
Designs for Health, Inc.
Street Address
980 South Street
City
Suffield
State
CT
ZipCode
06078
Web Address
www.designsforhealth.com
Pharmacist Counseling Corner

PharmaGABA Chewables by Designs for Health: Common Questions

Does PharmaGABA Chewables by Designs for Health interact with any medications?
Yes. Based on its ingredients, PharmaGABA Chewables has a known interaction with 419 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
PharmaGABA Chewables contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is GABA and what does it do in my body?
GABA is gamma-aminobutyric acid, a chemical messenger in your brain that helps calm your nervous system and promote relaxation. Your body makes it naturally, and this supplement provides an oral dose.
Can I take this if I'm pregnant?
There isn't enough safety information to know whether GABA is safe during pregnancy. Talk with your doctor before using it.
What are the most common side effects?
When taken by mouth, drowsiness, nausea, stomach upset, minor throat burning, and muscle weakness have been reported. Serious adverse effects are uncommon.
Does this product have any fillers?
Yes—it contains dextrose, magnesium stearate, natural flavors, citric acid, and silica as inactive ingredients that help form the chewable tablet.
Is there good evidence that GABA works for anxiety or ADHD?
No—we don't have reliable evidence to support how well it works for anxiety, ADHD, or the other conditions it's marketed for. If you're interested in it for one of those reasons, check with your doctor about what research actually shows.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if PharmaGABA Chewables is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

PharmaGABA Chewables label
Go deeper

The Full Monographs Behind PharmaGABA Chewables’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Gamma-aminobutyric Acid (gaba)

Interacts with 419 drugs

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep. The science behind oral GABA supplemen...

Read the full Gamma-aminobutyric Acid (gaba) monograph →
Sources

Sources & How We Checked

PharmaGABA Chewables's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gamma-aminobutyric Acid (gaba) 12 references
  1. Cavagnini F, Invitti C, Pinto M, et al. Effect of acute and repeated administration of gamma aminobutyric acid (GABA) on growth hormone and prolactin secretion in man. Acta Endocrinol (Copenh) 1980;93:149-54.
  2. Nurnberger JI Jr, Berrettini WH, Simmons-Alling S, et al. Intravenous GABA administration is anxiogenic in man. Psychiatry Res 1986;19:113-7. PubMed
  3. Gershman RN, Vasilenko MA, Iliushina GG, et al. [Gammalon in the rehabilitation in infantile cerebral palsy]. Pediatr.Akus.Ginekol. 1977;(6):26-7.
  4. Loeb C, Benassi E, Bo, GP, et al. Preliminary evaluation of the effect of GABA and phosphatidylserine in epileptic patients. Epilepsy Res. 1987;1:209-12 . PubMed
  5. Inoue K, Shirai T, Ochiai H, et al. Blood-pressure-lowering effect of a novel fermented milk containing gamma-aminobutyric acid (GABA) in mild hypertensives. Eur J Clin Nutr 2003;57:490-95.
  6. ELLIOTT, K. A. and JASPER, H. H. Gammaaminobutyric acid. Physiol Rev. 1959;39(2):383-406.
  7. Winsky-Sommerer, R. Role of GABAA receptors in the physiology and pharmacology of sleep. Eur.J.Neurosci. 2009;29(9):1779-1794.
  8. Meldrum, B. S. GABAergic mechanisms in the pathogenesis and treatment of epilepsy. Br.J.Clin.Pharmacol. 1989;27 Suppl 1:3S-11S. PubMed
  9. Loeb, C., Marinari, U. M., Benassi, E., Besio, G., Cottalasso, D., Cupello, A., Maffini, M., Mainardi, P., Pronzato, M. A., and Scotto, P. A. Phosphatidylserine increases in vivo the synaptosomal uptake of exogenous GABA in rats. Exp.Neurol. 1988;99(2):4 PubMed
  10. Melis, G. B., Paoletti, A. M., Mais, V., and Fioretti, P. Interference of dopamine infusion on gamma-amino butyric acid (GABA)-stimulated prolactin increase. J.Endocrinol.Invest 1980;3(4):445-448.
  11. Boonstra E, de Kleijn R, Colzato LS, Alkemade A, Forstmann BU, Nieuwenhuis S. Neurotransmitters as food supplements: the effects of GABA on brain and behavior. Front Psychol. 2015 Oct 6;6:1520. doi: 10.3389/fpsyg.2015.01520. eCollection 2015. PubMed
  12. de Bie TH, Witkamp RF, Balvers MG, Jongsma MA. Effects of ?-aminobutyric acid supplementation on glucose control in adults with prediabetes: A double-blind, randomized, placebo-controlled trial. Am J Clin Nutr 2023;118(3):708-719. PubMed

See these in context on the Gamma-aminobutyric Acid (gaba) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team