No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Natural Biotin 2.5 mg (2500 mcg) Ingredients & Drug Interactions

by Freeda

Tablet Or Pill Category: Vitamin
No known interaction
The interaction bottom line No known interaction

Natural Biotin 2.5 mg (2500 mcg) is a dietary supplement by Freeda with 1 active ingredient. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Natural Biotin 2.5 mg (2500 mcg) by Freeda

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: D-Biotin (also called biotin), a B vitamin at a dose of 2.5 mg (2500 mcg) per tablet. The inactive ingredients are cellulose, calcium phosphate, vegetarian stearate, silica, and croscarmellose sodium — these are fillers and binders that help hold the tablet together.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Biotin's overall clinical evidence instead.

Strong

Strong clinical evidence supports Biotin for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Biotin deficiency — rated "Likely Effective" (Natural Medicines).

Biotin is likely effective for treating biotin deficiency itself. For other uses — multiple sclerosis, seborrheic dermatitis (a scaly skin condition), and alopecia areata (patchy hair loss) — the evidence either suggests it probably won't help (MS and seborrheic dermatitis) or there isn't enough reliable evidence to say (alopecia areata).

If you're taking this for one of those other conditions, talk with your doctor about what the research actually supports.

The evidence, ingredient by ingredient Biotin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Biotin is generally well tolerated, even at fairly high doses, because your body removes the excess in your urine. High-dose biotin has rarely caused mild diarrhea — only a small number of people taking very high doses (like 300 mg daily) reported it.

There is one isolated case report of a woman who developed inflammation in the lining around the heart and lungs after taking biotin along with another supplement and a heart medication, but it's unclear what actually caused it, and no similar cases have been reported since. The safety notes advise checking with your doctor before taking high-dose supplements, especially if you're not deficient in biotin.

Side effects, ingredient by ingredient Biotin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check in this product. Still, use the search tool on this page to verify your exact medications, and talk with your doctor or pharmacist before starting if you're on any prescription drug or have questions.

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

This is a straightforward biotin supplement — good if you actually have a biotin deficiency and tolerate the dose well. It's generally safe even at higher levels, though the manufacturer recommends checking with your doctor before you start, particularly if you're taking it at this higher dose.

If you're considering it for hair loss, skin problems, or multiple sclerosis, the evidence is weak or negative, so have that conversation with your doctor first. Run your medications through the tool on this page, then confirm with your own doctor or pharmacist that it makes sense for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Natural Biotin 2.5 mg (2500 mcg), straight from the product label.

Brand Freeda
Barcode (UPC) 758487029617
Net contents 100 Tablet(s)
Market status On market
Date entered into DSLD May 22, 2020
DSLD ID 221431
Product type Vitamin
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Natural Biotin 2.5 mg (2500 mcg) by Freeda, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
UPC/BARCODE
758487029617
IngredientAmount% DV
D-Biotin2500 mcg8333%

Other ingredients: Cellulose, Calcium Phosphate, Vegetarian Stearate, Silica, Croscarmellose Sodium

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

No gluten No lactose No artificial colors No artificial flavors No animal derivatives No sugar or starch No gelatin No yeast

Vegan

Seals/Symbols

Manufactured in a GMP certified facility in the USA

NSKC (New Square Rabbinical Kashrus Council) OU Pareve (Kosher)

General Statements

Freeda since 1928

FDA Statement of Identity

Vitamin Supplement

Formula

NSKC (New Square Rabbinical Kashrus Council) OU Pareve (Kosher)

Suggested/Recommended/Usage/Directions

Suggested Use: Adults, take one (1) tablet daily preferably with food and liquid.

Storage

Store product at room temperature. Do not expose to excessive heat or moisture.

Precautions

Keep this product out of the reach of children.

See for yourself

Natural Biotin 2.5 mg (2500 mcg) by Freeda label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Natural Biotin 2.5 mg (2500 mcg) by Freeda

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

D-Biotin

No known
interactions
2500 mcg per serving

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

D-Biotin monograph & interactions

Other (inactive) ingredients: Cellulose, Calcium Phosphate, Vegetarian Stearate, Silica, Croscarmellose Sodium. These complete the product’s ingredient list but are not active constituents.

Interaction report

Natural Biotin 2.5 mg (2500 mcg) by Freeda Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Natural Biotin 2.5 mg (2500 mcg). This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Natural Biotin 2.5 mg (2500 mcg), from the product label.

Freeda

See all Freeda products
Name
Freeda Health
City
Brooklyn
State
NY
ZipCode
11210
Phone Number
1-800-777-3737
Web Address
www.freedahealth.com
Pharmacist Counseling Corner

Natural Biotin 2.5 mg (2500 mcg) by Freeda: Common Questions

Does Natural Biotin 2.5 mg (2500 mcg) by Freeda interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Natural Biotin 2.5 mg (2500 mcg). This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Natural Biotin 2.5 mg (2500 mcg) contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is biotin, and why would I take it?
Biotin is a B vitamin that your body needs for healthy hair, skin, and nails. This product is most useful if you actually have a biotin deficiency — a rare condition — but some people take it hoping it'll help with hair loss or skin issues even though the evidence for those uses is weak or doesn't support it.
Is this safe to take while pregnant or breastfeeding?
Biotin is rated likely safe during pregnancy and lactation. The amounts you get from food and prenatal vitamins are appropriate, but if you're thinking about taking this higher-dose supplement on your own, talk with your doctor first.
What are the side effects?
Biotin is generally well tolerated. High-dose biotin has rarely caused mild diarrhea in a small number of people. There's one isolated case report of inflammation around the heart and lungs, but it's unclear whether biotin caused it, and it hasn't been reported since.
Can biotin help with hair loss or skin problems?
The evidence doesn't support biotin for seborrheic dermatitis or multiple sclerosis. For alopecia areata (patchy hair loss), there isn't enough reliable evidence to say whether it works. If you're taking this for one of those reasons, discuss what the research actually shows with your doctor.
Why do I need to check with my doctor about the dose?
This is a high-dose biotin supplement — much more than you'd get from food. The safety notes recommend checking with your doctor before taking it, especially if you don't have an actual biotin deficiency.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Natural Biotin 2.5 mg (2500 mcg) is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Natural Biotin 2.5 mg (2500 mcg) label
Go deeper

The Full Monographs Behind Natural Biotin 2.5 mg (2500 mcg)’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Natural Biotin 2.5 mg (2500 mcg)'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring