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Dietary supplement

Natural Vitamin K2 MK-7 with MenaQ7 45 mcg Ingredients & Drug Interactions

by Doctor's Best

Natural Vitamin K2 MK-7 with MenaQ7 45 mcg label
See full label image
Capsule Category: Vitamin
Most serious interaction: Major
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Natural Vitamin K2 MK-7 with MenaQ7 45 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Natural Vitamin K2 MK-7 with MenaQ7 45 mcg is a dietary supplement by Doctor's Best with 1 active ingredient. Its ingredients are commonly taken for supporting normal blood clotting, bone health, heart and vascular health.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin K2. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Natural Vitamin K2 MK-7 with MenaQ7 45 mcg by Doctor's Best

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HelloPharmacist Scorecard of Natural Vitamin K2 MK-7 with MenaQ7 45 mcg by Doctor's Best

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: vitamin K2 (as MenaQ7) at 45 micrograms per capsule. Vitamin K2 is a form of vitamin K that your body uses to activate proteins involved in blood clotting and bone mineralization.

The capsule also contains inactive ingredients — microcrystalline cellulose, modified cellulose, glycerol monostearate, magnesium stearate, ascorbyl palmitate, and rosemary extract — which serve as binders, fillers, and preservatives.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: bone health and soft tissue support.
  • We looked for evidence on: Osteoporosis, bone mineralization, fracture prevention, bone density.
  • The strongest evidence on file: Vitamin K is rated "Possibly Effective" for Osteoporosis (Natural Medicines).

Vitamin K2 is effective for treating vitamin K deficiency conditions, including low blood clotting factors (hypoprothrombinemia and vitamin K-dependent clotting factors deficiency) and hemorrhagic disease. For osteoporosis, the evidence shows it is possibly effective — meaning there is some research support, but more evidence is needed to confirm benefit.

The evidence, ingredient by ingredient Vitamin K

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taken by mouth, vitamin K is generally well tolerated. The most common side effects are mild: nausea, diarrhea, stomach upset, and abdominal pain.

These occur in a small number of people. The safety data rates vitamin K as likely safe in pregnancy and lactation.

That said, normal dietary amounts are fine, but you should check with your doctor or pharmacist before taking supplements of any kind.

Side effects, ingredient by ingredient Vitamin K

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin K.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take warfarin (Coumadin) or any other blood thinner medication. Vitamin K can reduce their effectiveness, and your doses may need adjustment.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This supplement is a straightforward source of vitamin K2 for people whose diets may be low in it or who have a documented vitamin K deficiency. If you take warfarin or any other blood thinner, you must talk with your doctor or pharmacist before starting — vitamin K can interfere with how these drugs work.

For anyone else, it's generally well tolerated, though some people may experience mild digestive upset.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Natural Vitamin K2 MK-7 with MenaQ7 45 mcg, straight from the product label.

Brand Doctor's Best
Barcode (UPC) 753950001985
Net contents 60 Veggie Cap(s)
Market status On market
Date entered into DSLD Jun 24, 2019
DSLD ID 203155
Product type Vitamin
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Natural Vitamin K2 MK-7 with MenaQ7 45 mcg by Doctor's Best, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
Servings per container
60
UPC/BARCODE
753950001985
IngredientAmount% DV
Vitamin K245 mcg40%

Other ingredients: Microcrystalline Cellulose, Modified Cellulose, Glycerol Monostearate, Magnesium Stearate, Ascorbyl Palmitate, Rosemary extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Doctor’s Best Natural Vitamin K2 MK-7 with MenaQ7 provides the natural form of vitamin K for optimum bioavailability and delivery to the body.

Vitamin K isn’t one vitamin, it’s a family of fat-soluble vitamins with similar chemical structures but different metabolic properties. K2 belongs to a group of vitamin K compounds called menaquinones, which show greater bioactivity when compared to K1, the ordinary supplemental form. K2 is absorbed more completely, remains in the body longer and delivers more benefits for bones, blood vessels and other soft tissues.

Highly effective delivery of vitamin K to bone and soft tissue

Natural Vitamin K2 MK-7 with MenaQ7 Vitamin K2 as MK-7 45 mcg

The bioavailable form of vitamin K for healthy bones and soft tissue.

Warning: This product contains vitamin K.

General Statements

Helps support bone health and soft tissue elasticity Helps support calcium metabolism for maintenance of healthy bone

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General

YDRB198-6

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Science-Based Nutrition

MenaQ7 is a registered trademark of NattoPharma ASA, Norway.

Seals/Symbols

Vegan

Formulation

Vegan

Non-GMO Gluten free Soy free

Suggested/Recommended/Usage/Directions

Suggested Adult Use: Take 1 capsule daily with food, or as recommended by a nutritionally-informed physician.

Precautions

Warning: This product contains vitamin K. Consult your physician if using blood-thinning medications such as Warfarin.

Storage

Store in a cool dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Natural Vitamin K2 MK-7 with MenaQ7 45 mcg by Doctor's Best label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Natural Vitamin K2 MK-7 with MenaQ7 45 mcg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Natural Vitamin K2 MK-7 with MenaQ7 45 mcg by Doctor's Best

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Vitamin K2

Interacts with
2 drugs
45 mcg per serving Form: MenaQ7 Menaquinone

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but suppl...

Vitamin K2 monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Modified Cellulose, Glycerol Monostearate, Magnesium Stearate, Ascorbyl Palmitate, Rosemary extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Natural Vitamin K2 MK-7 with MenaQ7 45 mcg by Doctor's Best Drug Interactions

Want to check YOUR meds against Natural Vitamin K2 MK-7 with MenaQ7 45 mcg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2Drugs
2 Major

Ingredients driving the most interactions

Vitamin K2 2

Individual Drug Interactions

The ingredients in Natural Vitamin K2 MK-7 with MenaQ7 45 mcg interact with 2 drugs. Click any drug to see the details.

1 of the 1 ingredient in Natural Vitamin K2 MK-7 with MenaQ7 45 mcg interact with drugs. Each result below shows which ingredient is responsible. Vitamin K2

Each ingredient & the kinds of drugs it affects

For each ingredient in Natural Vitamin K2 MK-7 with MenaQ7 45 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin K21 drug type · 2 drugs

Warfarin (Coumadin)

Vitamin K can antagonize and reverse the therapeutic effects of warfarin.
Vitamin K antagonizes the effects of warfarin. Excessive vitamin K intake, either from supplements or from changes in the diet, can reduce the anticoagulant effect of warfarin.

Likelihood Likely Evidence C
Vitamin K2 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Natural Vitamin K2 MK-7 with MenaQ7 45 mcg, from the product label.

Doctor's Best

See all Doctor's Best products
Name
Doctor's Best, Inc.
State
California
ZipCode
92612
Phone Number
(800) 777-2474
Web Address
www.drbvitamins.com
Pharmacist Counseling Corner

Natural Vitamin K2 MK-7 with MenaQ7 45 mcg by Doctor's Best: Common Questions

Does Natural Vitamin K2 MK-7 with MenaQ7 45 mcg by Doctor's Best interact with any medications?
Yes. Based on its ingredients, Natural Vitamin K2 MK-7 with MenaQ7 45 mcg has a known interaction with 2 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Natural Vitamin K2 MK-7 with MenaQ7 45 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Yes, the safety data rates vitamin K as likely safe during pregnancy and lactation. However, every pregnancy is individual — if you have questions about whether it's right for you, talk it over with your doctor or pharmacist.
What's the difference between vitamin K1 and K2?
Both are forms of vitamin K, but K2 (like the MenaQ7 in this product) is often found in fermented foods and animal products, while K1 is more common in leafy greens. The body handles them slightly differently, and K2 may have particular roles in bone and cardiovascular health.
Will this supplement cause side effects?
Most people tolerate vitamin K well. When side effects do occur, they're usually mild — nausea, diarrhea, stomach upset, or abdominal pain — and they're not common. If you notice any of these after starting, let your doctor know.
Does this help with osteoporosis?
The research suggests vitamin K2 is possibly effective for osteoporosis, meaning there's some evidence it may help, but more studies are needed to confirm the benefit. It's not a standalone treatment — talk with your doctor about whether it fits into your overall bone health plan.
Why does the label say to check with my doctor before taking supplements?
Because vitamin K can interact with blood thinners like warfarin, and even normal dietary changes in vitamin K intake can affect how those drugs work. Your doctor or pharmacist needs to know what you're taking so they can make sure it's safe with your other medications.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Natural Vitamin K2 MK-7 with MenaQ7 45 mcg label
Go deeper

The Full Monographs Behind Natural Vitamin K2 MK-7 with MenaQ7 45 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin K

Interacts with 2 drugs

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but supplements are sometimes used for deficiency...

Read the full Vitamin K monograph →
Sources

Sources & How We Checked

Natural Vitamin K2 MK-7 with MenaQ7 45 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin K 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Crowther MA, Ageno W, Garcia D, et al. Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial. Ann Intern Med. 2009;150(5):293-300. PubMed
  4. Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation? Nutr Rev. 2010;68(3):178-81. PubMed
  5. Kim JS, Nafziger AN, Gaedigk A, et al. Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe. J Clin Pharmacol. 2001 Jul;41(7):715-22. PubMed
  6. Riegert-Johnson, D. L. and Volcheck, G. W. The incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective review. Ann.Allergy Asthma Immunol. 2002;89(4):400-406. PubMed
  7. Dezee, K. J., Shimeall, W. T., Douglas, K. M., Shumway, N. M., and O'malley, P. G. Treatment of excessive anticoagulation with phytonadione (vitamin K): a meta-analysis. Arch.Intern.Med. 2-27-2006;166(4):391-397. DOI
  8. Dentali, F., Ageno, W., and Crowther, M. Treatment of coumarin-associated coagulopathy: a systematic review and proposed treatment algorithms. J.Thromb.Haemost. 2006;4(9):1853-1863. PubMed
  9. Stevenson, M., Lloyd-Jones, M., and Papaioannou, D. Vitamin K to prevent fractures in older women: systematic review and economic evaluation. Health Technol.Assess. 2009;13(45):iii-134. PubMed
  10. Caluwé R, Vandecasteele S, Van Vlem B, Vermeer C, De Vriese AS. Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study. Nephrol Dial Transplant. 2014;29(7):1385-90.
  11. Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, Fan SW. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials. Osteoporos Int. 2015;26(3):1175-86. PubMed
  12. Hunnali CR, Devi U, Kitchanan S, Sethuraman G. Three Different Regimens for Vitamin K Birth Prophylaxis in Infants Born Preterm: A Randomized Clinical Trial. J Pediatr 2023;255:98-104. PubMed

See these in context on the Vitamin K monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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