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Dietary supplement

NewVigor Boost Ingredients & Drug Interactions

by Vitalast

NewVigor Boost label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking NewVigor Boost against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

NewVigor Boost is a dietary supplement by Vitalast with 2 active ingredients. Its ingredients are commonly taken for low libido or sexual performance, erectile difficulties, general energy and fatigue.Based on those ingredients, 965 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Horny Goat Weed extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against NewVigor Boost by Vitalast

Ask about any prescription or over-the-counter medication and we check it for interactions with NewVigor Boost by Vitalast — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of NewVigor Boost by Vitalast

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

NewVigor Boost contains two active herbal ingredients: a Brazilian Catuaba 4:1 extract and a Horny Goat Weed extract. The product is made in capsule form with inactive ingredients including gelatin, rice flour, magnesium stearate, and silicon dioxide.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: sexual performance and erectile function.
  • We looked for evidence on: Erectile dysfunction (ED), Sexual dysfunction, Male infertility, Libido, Vitality.
  • The closest evidence on file: Horny Goat Weed is rated "Insufficient Reliable Evidence To Rate" for Sexual dysfunction (Natural Medicines).
  • Also on file: Horny Goat Weed is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED), Male infertility.

The evidence for both ingredients is not established in the data we hold. Horny Goat Weed has been studied for sexual dysfunction, bronchitis, osteoporosis, and heart health, but the evidence is insufficient to rate its effectiveness for any of these uses.

Brazilian Catuaba's effectiveness data are similarly not on file.

The evidence, ingredient by ingredient Catuaba Horny Goat Weed

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Horny Goat Weed appears to be generally well tolerated when used short-term, though quality varies between products. The most common side effects reported are dizziness, dry mouth, nosebleed, thirst, and vomiting.

Long-term use has been linked to reports of vomiting, dry mouth, thirst, and nosebleed. A rare case of heart rhythm problems (tachyarrhythmia) was reported in one man after two weeks of use, though it's unclear whether horny goat weed alone was responsible.

Brazilian Catuaba's human safety data are very limited, and long-term safety is not well established. Brazilian Catuaba is best avoided during pregnancy and while breastfeeding due to insufficient safety information.

Horny Goat Weed also lacks enough safety data and should be avoided in both pregnancy and breastfeeding.

Side effects, ingredient by ingredient Catuaba Horny Goat Weed

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Horny Goat Weed.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 966 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking NewVigor Boost, check with your pharmacist if you use blood pressure medications, blood thinners or antiplatelet drugs (like warfarin or aspirin), estrogen-containing medications or birth control, or any drug your liver breaks down — particularly those processed through CYP1A2, CYP2B6, or CYP3A4 enzymes. These are all theoretical risks based on lab research, not yet proven in people, but worth discussing.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is marketed toward sexual health, but the evidence for either ingredient isn't strong enough to establish whether it works. The bigger concern is that Horny Goat Weed can interact with common medications — blood pressure drugs, blood thinners, birth control, and many others processed through your liver.

Talk to your pharmacist before you start, especially if you take any prescription medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about NewVigor Boost, straight from the product label.

Brand Vitalast
Barcode (UPC) 013964468564
Net contents 50 Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2018
DSLD ID 82940
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for NewVigor Boost by Vitalast, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
25
UPC/BARCODE
013964468564
IngredientAmount% DV
Brazilian Catuaba 4:1 extract250 mg--
Horny Goat Weed extract500 mg--

Other ingredients: Gelatin, Rice Flour, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

High potency Horny Goat Weed Standardized to contain 20% pure Icariin.

True Catuaba We use true Erthroxylum catuaba.

High potency Horny Goat Weed standardized to contain 20% Icariin plus true Catuaba extract

General Statements

Most other products are standardized to less, or to icariins (icariin and other compounds), or are not standardized at all.

Other catuaba products often use different, related herbs instead.

Suggested/Recommended/Usage/Directions

Suggested Adult Use: 2 capsules daily, 4 days on, 3 days off. Take by itself or with our NewVigor daily supplement.

FDA Statement of Identity

Dietary Supplement

Precautions

Keep out of the reach of children.

If you have a health condition or are taking medication, or are pregnant or nursing, consult your doctor before taking.

Discontinue use if adverse reaction occurs. Do not use if seal is broken or missing.

Storage

Store in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

NewVigor Boost by Vitalast label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

NewVigor Boost label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in NewVigor Boost by Vitalast

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container25 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Brazilian Catuaba 4:1 extract

No known
interactions
250 mg per serving

Catuaba is a Brazilian herbal bark long used as a traditional aphrodisiac and energy tonic, but there is very little reliable human research to show i...

Brazilian Catuaba 4:1 extract monograph & interactions

Horny Goat Weed extract

Interacts with
965 drugs
500 mg per serving Form: Icariin

Horny goat weed (Epimedium) is a traditional Chinese herb most often marketed for low libido and erectile problems, but solid human evidence for these...

Horny Goat Weed extract monograph & interactions

Other (inactive) ingredients: Gelatin, Rice Flour, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

NewVigor Boost by Vitalast Drug Interactions

Want to check YOUR meds against NewVigor Boost?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
965Drugs
965 Moderate

Ingredients driving the most interactions

Horny Goat Weed extract 965

Individual Drug Interactions

The ingredients in NewVigor Boost interact with 965 drugs. Click any drug to see the details.

1 of the 2 ingredients in NewVigor Boost interact with drugs. Each result below shows which ingredient is responsible. Horny Goat Weed extract

Each ingredient & the kinds of drugs it affects

For each ingredient in NewVigor Boost with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Horny Goat Weed extract6 drug types · 965 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, horny goat weed might increase the risk of bleeding.
In vitro research and animal research shows that horny goat weed can inhibit platelet aggregation and thrombus formation. This effect has not been reported in humans.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, horny goat weed might increase the risk of hypotension.
Laboratory research suggests that horny goat weed might have hypotensive effects. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, horny goat weed might increase the effects and side effects of CYP1A2 substrates.
In vitro, horny goat weed leaf extract inhibits CYP1A2. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, horny goat weed might increase the effects and side effects of CYP2B6 substrates.
In vitro, horny goat weed leaf extract inhibits CYP2B6. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, horny goat weed might increase the effects and side effects of CYP3A4 substrates.
In vitro, horny goat weed extract inhibits CYP3A4 and suppresses CYP3A4 mRNA expression. This effect has not been reported in humans.

Likelihood Possible Evidence D
Estrogens

Theoretically, concomitant use of horny goat weed with estrogens might increase their therapeutic and adverse effects.
In vitro evidence suggests that horny goat weed has estrogenic activity. In clinical research, horny goat weed has been shown to increase blood levels of estrogen in some females.

Likelihood Possible Evidence D
Horny Goat Weed extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for NewVigor Boost, from the product label.

Vitalast

See all Vitalast products
Name
Vitalast LLC
Street Address
PO Box 385
City
Pound Ridge
State
NY
ZipCode
10576
Web Address
www.NewVigor.com/boost
Pharmacist Counseling Corner

NewVigor Boost by Vitalast: Common Questions

Does NewVigor Boost by Vitalast interact with any medications?
Yes. Based on its ingredients, NewVigor Boost has a known interaction with 965 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
NewVigor Boost contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or nursing?
No. Both ingredients lack enough safety data, and the safety information we have advises against use during pregnancy and while breastfeeding. Talk with your doctor or pharmacist about what's safe for you.
What are the most common side effects?
Horny Goat Weed, the ingredient with documented side effects, most commonly causes dizziness, dry mouth, nosebleed, thirst, and vomiting. Longer-term use has been linked to similar reports. A very rare serious case of heart rhythm problems was reported.
Does this actually work for sexual dysfunction?
The evidence isn't strong enough to say. Horny Goat Weed has been studied for sexual dysfunction, but current data are insufficient to rate whether it's effective. Same goes for Brazilian Catuaba — we don't have effectiveness ratings on file for it.
Why does this have so many medication interactions listed?
Horny Goat Weed can affect three liver enzymes that break down hundreds of different medications. That's why the total count is so high — it's the same few pathways affecting many different drugs. Your specific medications may or may not be affected.
Is Brazilian Catuaba safe?
Human safety data are very limited, and long-term safety isn't well established. We also couldn't check it for medication interactions. If you're interested in this product, talk with your pharmacist first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

NewVigor Boost label
Go deeper

The Full Monographs Behind NewVigor Boost’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Catuaba

Catuaba is a Brazilian herbal bark long used as a traditional aphrodisiac and energy tonic, but there is very little reliable human research to show it works for any health condition. Qualit...

Read the full Catuaba monograph → Herb & supplement monograph

Horny Goat Weed

Interacts with 965 drugs

Horny goat weed (Epimedium) is a traditional Chinese herb most often marketed for low libido and erectile problems, but solid human evidence for these uses is lacking. While short-term use s...

Read the full Horny Goat Weed monograph →
Sources

Sources & How We Checked

NewVigor Boost's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Horny Goat Weed 11 references
  1. Cirigliano MD, Szapary PO. Horny goat weed for erectile dysfunction. Alt Med Alert 2001;4:19-22.
  2. Partin JF, Pushkin YR. Tachyarrhythmia and hypomania with horny goat weed. Psychosomatics 2004;45:536-7. PubMed
  3. De Naeyer A, Pocock V, Milligan S, De Keukeleire D. Estrogenic activity of a polyphenolic extract of the leaves of Epimedium brevicornum. Fitoterapia 2005;76:35-40. PubMed
  4. Zhang CZ, Wang SX, Zhang Y, et al. In vitro estrogenic activities of Chinese medicinal plants traditionally used for the management of menopausal symptoms. J Ethnopharmacol 2005;98:295-300. PubMed
  5. Yap SP, Shen P, Li J, et al. Molecular and pharmacodynamic properties of estrogenic extracts from the traditional Chinese medicinal herb, Epimedium. J Ethnopharmacol 2007;113:218-24. PubMed
  6. Yan, F. F., Liu, Y., Liu, Y. F., and Zhao, Y. X. Herba Epimedii water extract elevates estrogen level and improves lipid metabolism in postmenopausal women. Phytother.Res. 2008;22(9):1224-1228. PubMed
  7. Ramanathan VS, Mitropoulos E, Shlopov B, et al. An Enzyte'ing' case of acute hepatitis. J Clin Gastroenterol 2011;45(9):834-5. PubMed
  8. Zhong Q, Shi Z, Zhang L, et al. The potential of Epimedium koreanum Nakai for herb-drug interaction. J Pharm Pharmacol 2017;69(10):1398-408. doi: 10.1111/jphp.12773.
  9. Irfan M, Kwon TH, Lee DH, et al. Antiplatelet and Antithrombotic Effects of Epimedium koreanum Nakai. Evid Based Complement Alternat Med. Apr 2021;2021:7071987. PubMed
  10. Tan K, Yang W, Pang L, Hou F. Differences in clinical characteristics among 726 patients with Chinese herbal medicine- or Western medicine-induced liver injury. Medicine (Baltimore) 2022;101(32):e29909. PubMed
  11. Li K, Yu XH, Maskey AR, et al. Cytochrome P450 3A4 suppression by epimedium and active compound kaempferol leads to synergistic anti-inflammatory effect with corticosteroid. Front Pharmacol 2023;13:1042756. PubMed

See these in context on the Horny Goat Weed monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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