No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

NK Cell Activator Ingredients & Drug Interactions

by Life Extension

NK Cell Activator label
See full label image
Tablet Or Pill Category: Fiber And Other Nutrients
No known interaction
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking NK Cell Activator against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

NK Cell Activator is a dietary supplement by Life Extension with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, digestive health and fiber, heart health support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

Jump to a section

HelloPharmacist Scorecard of NK Cell Activator by Life Extension

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product has one active ingredient: a proprietary enzymatically modified rice bran. The inactive ingredients are microcrystalline cellulose, maltodextrin, dicalcium phosphate, croscarmellose sodium, stearic acid, silica, hydroxypropyl cellulose, hydroxypropyl methylcellulose, glycerin, and stearate — the binders, fillers, and capsule materials that hold the tablet together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Rice Bran's overall clinical evidence instead.

Moderate

Some clinical evidence supports Rice Bran for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Dyslipidemia — rated "Possibly Effective" (Natural Medicines).

The evidence for rice bran centers on blood lipids — the fats in your blood. It's rated possibly effective for improving cholesterol and triglycerides.

For colorectal cancer prevention, the data suggests it's probably not effective. For hair loss (alopecia areata), there isn't enough reliable evidence to say whether it works or doesn't.

The evidence, ingredient by ingredient Rice Bran

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Rice bran is generally well tolerated when you eat it as food, but concentrated supplements have less safety data behind them. When you first increase the amount of bran you take, you may notice digestive effects — abdominal discomfort, bloating, and loose or unpredictable bowel movements — though these typically settle after a few weeks.

Allergic reactions are rare but possible; they range from itching and rash to serious reactions like anaphylaxis, particularly in people with rice allergies. During pregnancy and breastfeeding, rice bran is rated likely safe, though like any supplement at high doses, it's worth mentioning to your doctor or midwife.

Side effects, ingredient by ingredient Rice Bran

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for this product's ingredients.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

If you're interested in supporting cholesterol and triglyceride levels and tolerate rice bran well, this is a solid option. Start slowly to let your digestion adjust.

Skip it if you have a known rice allergy. Always let your pharmacist know you're taking it, especially if you're pregnant, breastfeeding, or managing any health conditions.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about NK Cell Activator, straight from the product label.

Brand Life Extension
Barcode (UPC) 737870190332
Net contents 30 Vegetarian Tablet(s)
Market status On market
Date entered into DSLD Jun 25, 2025
DSLD ID 328601
Product type Fiber And Other Nutrients
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for NK Cell Activator by Life Extension, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Tablet(s)
Maximum serving Sizes:
1 Vegetarian Tablet(s)
Servings per container
30
UPC/BARCODE
737870190332
IngredientAmount% DV
Proprietary Enzymatically Modified Rice Bran500 mg--

Other ingredients: Microcrystalline Cellulose, Maltodextrin, Dicalcium Phosphate, Croscarmellose Sodium, Stearic Acid, Silica, Hydroxypropyl Cellulose, Hydroxypropyl Methylcellulose, Glycerin, Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Scan for product info

Precautions

Read the entire label and follow the directions carefully prior to use.

Warnings: Keep out of reach of children.

Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Contains wheat.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Suggested/Recommended/Usage/Directions

Directions: Take one (1) tablet once or twice daily with food, or as recommended by a healthcare practitioner.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Gluten free Non GMO LE Certified

Supports healthy natural killer cell function

Seals/Symbols

Non GMO LE Certified

FDA Statement of Identity

Dietary Supplement

Storage

Store tightly closed in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

NK Cell Activator by Life Extension label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

NK Cell Activator label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in NK Cell Activator by Life Extension

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetarian Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Proprietary Enzymatically Modified Rice Bran

No known
interactions
500 mg per serving

Rice bran is the nutrient-rich outer layer of the rice grain and is a good source of fiber, healthy fats, and plant compounds. It is most studied for...

Proprietary Enzymatically Modified Rice Bran monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Maltodextrin, Dicalcium Phosphate, Croscarmellose Sodium, Stearic Acid, Silica, Hydroxypropyl Cellulose, Hydroxypropyl Methylcellulose, Glycerin, Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

NK Cell Activator by Life Extension Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in NK Cell Activator. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for NK Cell Activator, from the product label.

Life Extension

See all Life Extension products
Name
Quality Supplements and Vitamins, Inc.
City
Ft. Lauderdale
State
FL
ZipCode
33309
Phone Number
1-866-280-2852
Web Address
LifeExtension.com
Pharmacist Counseling Corner

NK Cell Activator by Life Extension: Common Questions

Does NK Cell Activator by Life Extension interact with any medications?
We do not currently list a known interaction for the mapped ingredients in NK Cell Activator. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
NK Cell Activator contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this give me digestive issues?
It might at first — some people notice bloating, gas, or loose stools when they start taking bran supplements. These effects are usually temporary and often settle down within a few weeks as your digestion adapts. Starting with a smaller dose can help.
Is it safe if I'm pregnant or breastfeeding?
Yes, rice bran is rated likely safe during pregnancy and breastfeeding. That said, like any supplement, it's smart to mention it to your doctor or midwife, especially if you're taking it at higher doses than you'd get from food.
What does this actually do?
The evidence is strongest for supporting healthy cholesterol and triglyceride levels — that's what it's rated possibly effective for. The data doesn't support it for colorectal cancer prevention, and there isn't enough reliable evidence yet on whether it helps with hair loss.
Can I be allergic to this?
Yes, though allergies are rare. If you have a rice allergy, you should avoid this product. Reactions can range from mild itching and rash to serious ones like anaphylaxis. If you've never had rice and notice wheezing, throat tightness, or severe swelling after taking it, seek medical help right away.
What's the proprietary enzymatically modified rice bran?
It's a concentrated form of rice bran that's been processed with enzymes to alter its structure. The idea is to make certain compounds in rice bran more available to your body, but the specifics of how it's modified aren't disclosed on the label.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if NK Cell Activator is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

NK Cell Activator label
Go deeper

The Full Monographs Behind NK Cell Activator’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Rice Bran

Rice bran is the nutrient-rich outer layer of the rice grain and is a good source of fiber, healthy fats, and plant compounds. It is most studied for helping lower cholesterol, but for most...

Read the full Rice Bran monograph →
Sources

Sources & How We Checked

NK Cell Activator's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rice Bran 7 references
  1. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  2. Fujiwaki T, Furusho K. The effects of rice bran broth bathing in patients with atopic dermatitis. Acta Paediatr Jpn 1992;34:505-10.
  3. Uenotsuchi T, Satoh E, Kiryu H, Yano Y. Pyemotes dermatitis caused by indirect contact with husk rice. Br J Dermatol 2000;143:680-2. DOI
  4. Satoh R, Tsuge I, Tokuda R, Teshima R. Analysis of the distribution of rice allergens in brown rice grains and of the allergenicity of products containing rice bran. Food Chem. 2019;276:761-767. PubMed
  5. Togashi Y, Inomata N, Suzuki A, Hakuta A, Aihara M. Pediatric case with rice bran allergy induced by epicutaneous sensitization in a family rice shop. Allergol Int. 2019;68(1):117-118. PubMed
  6. So WKW, Chan JYW, Law BMH, et al. Effects of a Rice Bran Dietary Intervention on the Composition of the Intestinal Microbiota of Adults with a High Risk of Colorectal Cancer: A Pilot Randomised-Controlled Trial. Nutrients 2021;13(2):526. PubMed
  7. Haneda Y, Kadowaki S, Furui M, Taketani T. A pediatric case of food-dependent exercise-induced anaphylaxis due to rice bran. Asia Pac Allergy 2021;11(1):e4. PubMed

See these in context on the Rice Bran monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team