NMN Ingredients & Drug Interactions
by Codeage
What is this page for?
First and foremost: checking NMN against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
NMN is a dietary supplement by Codeage with 2 active ingredients. Its ingredients are commonly taken for high homocysteine levels, liver health (fatty liver), exercise performance and strength.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of NMN by Codeage
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
NMN by Codeage has 2 active ingredients. Betaine anhydrous is an amino acid that your body uses to manage homocysteine (an amino acid in your blood) and support cellular function.
Beta-nicotinamide mononucleotide is a compound related to vitamin B3 that plays a role in energy production at the cellular level. The product also contains methylcellulose and sunflower oil as inactive ingredients.
Does it work?
Strong evidence
Betaine anhydrous is effective for homocystinuria (a rare genetic condition affecting amino acid metabolism) and possibly effective for high homocysteine levels in the blood. For other uses listed—including fatty liver disease (NASH), colorectal adenoma, depression, and GERD—the evidence isn't strong enough to rate.
We hold no effectiveness data for beta-nicotinamide mononucleotide in our current information.
How safe is it?
Well-documented data
Betaine anhydrous is generally well tolerated at studied doses, but safety data is limited and a healthcare provider should advise before use. The most common side effects are body odor, diarrhea, nausea, vomiting, GI distress, and elevated cholesterol levels.
Rarely, it can cause serious swelling in the brain (cerebral edema). Safety data during breastfeeding isn't well established, so caution is advised if you're nursing.
We hold no safety data for beta-nicotinamide mononucleotide.
Meds to double-check
No known interactions
No interactions are documented for the ingredients we could check. We cannot verify interactions for beta-nicotinamide mononucleotide.
If you take any medications, confirm with your doctor or pharmacist that this product is right for you.
The bottom line
Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.
NMN by Codeage is established for treating homocystinuria and possibly helpful for high homocysteine levels, but evidence for other uses isn't clear. If you're pregnant or breastfeeding, talk with your doctor or pharmacist before taking it, since safety data is limited.
Before starting, check with your doctor or pharmacist about your specific medications and health situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about NMN, straight from the product label.
| Brand | Codeage |
|---|---|
| Barcode (UPC) | 850026121827 |
| Net contents | 30 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2023 |
| DSLD ID | 298416 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for NMN by Codeage, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Betaine Anhydrous | 42.5 mg | -- |
| Beta-Nicotinamide Mononucleotide | 207.5 mg | -- |
Other ingredients: Methylcellulose, Sunflower Oil
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
NMN & TMG
Beta-Nicotinamide Mononucleotide
Formulation
Liposomal Blend
Non GMO
Seals/Symbols
cGMP Certified
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested Use: Take 1 capsule daily with 8 ounces of water or your favorite beverage. May be taken with or without food.
Brand IP Statement(s)
Copyright Codeage LLC. All rights reserved.
Precautions
Caution: Do not exceed recommended dose.
Pregnant or nursing mothers, children under 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Pregnant or nursing mothers, children under 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Please use caution if you have allergies or sensitivities to any of the listed ingredients.
Do not use if product has been opened or tampered with in any way. Keep out of reach of children and pets.
Keep out of reach of children and pets.
General Statements
Questions? Codeage.com
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Storage
Store in a cool, dry place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
NMN by Codeage label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in NMN by Codeage
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Betaine Anhydrous
No knowninteractions
Betaine anhydrous (also called trimethylglycine) is a compound found in foods like beets, spinach, and whole grains, and is sold as a supplement and a...
Betaine Anhydrous monograph & interactionsBeta-Nicotinamide Mononucleotide
Other (inactive) ingredients: Methylcellulose, Sunflower Oil. These complete the product’s ingredient list but are not active constituents.
NMN by Codeage Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in NMN. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for NMN, from the product label.
Codeage
See all Codeage products- Name
- Codeage LLC
- Street Address
- 5628 Washington Blvd
- City
- Los Angeles
- State
- CA
- ZipCode
- 90016
- Web Address
- www.codeage.com
NMN by Codeage: Common Questions
Does NMN by Codeage interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is betaine anhydrous supposed to do?
What are the most common side effects?
Is it safe to take if I'm breastfeeding?
What is beta-nicotinamide mononucleotide?
Are there any fillers in this product?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if NMN is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind NMN’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
NMN's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 11 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Betaine Anhydrous 11 references
- Cystadane (betaine anhydrous for oral solution) Package insert. Orphan Medical, Inc. Minnetonka, MN. November 2005.
- Abdelmalek MF, Angulo P, Jorgensen RA, et al. Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study. Am J Gastroenterol 2001;96:2711-7.. PubMed
- Schwab U, Torronen A, Toppinen L, et al. Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects. Am J Clin Nutr 2002;76:961-7. PubMed
- McGregor DO, Dellow WJ, Robson RA, et al. Betaine supplementation decreases post-methionine hyperhomocysteinemia in chronic renal failure. Kidney Int 2002;61:1040-6. PubMed
- Olthof MR, van Vliet T, Verhoef P, et al. Effect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humans. PloS Med 2005;2:e135. PubMed
- Knopman, D. and Patterson, M. An open-label, 24-week pilot study of the methyl donor betaine in Alzheimer disease patients. Alzheimer Dis.Assoc.Disord. 2001;15(3):162-165. PubMed
- Moat, S. J., Madhavan, A., Taylor, S. Y., Payne, N., Allen, R. H., Stabler, S. P., Goodfellow, J., McDowell, I. F., Lewis, M. J., and Lang, D. High- but not low-dose folic acid improves endothelial function in coronary artery disease. Eur J Clin Invest 2 PubMed
- Abdelmalek, M. F., Sanderson, S. O., Angulo, P., Soldevila-Pico, C., Liu, C., Peter, J., Keach, J., Cave, M., Chen, T., McClain, C. J., and Lindor, K. D. Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial. Hepa PubMed
- Ashtary-Larky D, Bagheri R, Ghanavati M, et al. Effects of betaine supplementation on cardiovascular markers: a systematic review and meta-analysis. Crit Rev Food Sci Nutr. 2021 Mar 25:1-18. PubMed
- Zawieja EE, Zawieja B, Chmurzynska A. Betaine supplementation moderately increases total cholesterol levels: a systematic review and meta-analysis. J Diet Suppl. 2021;18(1):105-117. PubMed
- Imbard A, Toumazi A, Magréault S, et al. Efficacy and pharmacokinetics of betaine in CBS and cblC deficiencies: a cross-over randomized controlled trial. Orphanet J Rare Dis 2022;17(1):417. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC