No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Organic D-Mannose Powder Ingredients & Drug Interactions

by Micro Ingredients

Powder Category: Fiber And Other Nutrients
No known interaction
The interaction bottom line No known interaction

Organic D-Mannose Powder is a dietary supplement by Micro Ingredients with 2 active ingredients. Its ingredients are commonly taken for preventing urinary tract infections (utis), treating mild utis, urinary tract health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Organic D-Mannose Powder by Micro Ingredients

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains a single active ingredient: D-mannose, a simple sugar. It has no inactive fillers or other added ingredients.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: Supports urinary tract health.
  • We looked for evidence on: Urinary tract infections (UTIs), urinary tract infections, cystitis, lower urinary tract symptoms.
  • The closest evidence on file: D-mannose is rated "Possibly Ineffective" for Urinary tract infections (UTIs) (Natural Medicines).

The evidence for D-mannose is mixed. For carbohydrate-deficient glycoprotein syndrome type 1b — a rare genetic condition — it's likely effective.

For urinary tract infections (UTIs), the research suggests it's possibly ineffective, so it's not a reliable choice if that's what you're after.

The evidence, ingredient by ingredient D-mannose

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

D-mannose is generally well tolerated short-term, but high-quality long-term safety data are limited, so caution is advised if you're thinking of taking it long-term. The most common side effects are bloating, diarrhea, and nausea.

Diarrhea risk increases with higher doses — a single dose greater than 200 mg/kg is more likely to trigger osmotic diarrhea (loose stools from fluid drawn into the bowel). Safety data during pregnancy are not adequate, so it's best to avoid unless your doctor advises otherwise.

Safety while breastfeeding is not well studied, so caution is advised — talk with your doctor or pharmacist for personalized guidance.

Side effects, ingredient by ingredient D-mannose

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for D-mannose. Still, run your medications through the search tool on this page before you start, just to be sure.

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

D-mannose may be worth considering if you have carbohydrate-deficient glycoprotein syndrome type 1b under medical supervision, but the evidence doesn't support it for UTIs. If you're pregnant, breastfeeding, or planning to take it long-term, check with your doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic D-Mannose Powder, straight from the product label.

Brand Micro Ingredients
Barcode (UPC) X001EO9QUR
Net contents 100 Gram(s); 3.53 Ounce(s)
Market status On market
Date entered into DSLD Aug 23, 2020
DSLD ID 231536
Product type Fiber And Other Nutrients
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic D-Mannose Powder by Micro Ingredients, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gram(s)
Maximum serving Sizes:
2 Gram(s)
Servings per container
50
UPC/BARCODE
X001EO9QUR
IngredientAmount% DV
Calories10 Calorie(s)--
Total Carbohydrates2 Gram(s)--
Sugar2 Gram(s)--
D-Mannose2 Gram(s)--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

USDA Organic

Kosher

Formulation

USDA Organic

Supports urinary tract health

Non-GMO No preservatives Additives free Fillers free Gluten-free

Free of: soy, dairy, yeast, gluten & additives.

Certified organic by Organic Certifiers

FDA Statement of Identity

Dietary Supplement

Formula

Kosher

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 1 scoop twice daily with water, or as directed by a physician.

Precautions

Keep out of the reach of children.

If pregnant/lactating or taking any medications, please consult your physician prior to use.

Storage

Keep in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Organic D-Mannose Powder by Micro Ingredients label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Organic D-Mannose Powder by Micro Ingredients

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Gram(s) Dosage formPowder Servings per container50 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

2 Gram(s) per serving

D-Mannose

No known
interactions
2 Gram(s) per serving

D-mannose is a natural sugar most often used to help prevent urinary tract infections, especially those caused by E. coli. Early research is promising...

D-Mannose monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Organic D-Mannose Powder by Micro Ingredients Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Organic D-Mannose Powder. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Organic D-Mannose Powder, from the product label.

Micro Ingredients

See all Micro Ingredients products
Name
Micro Ingredients
Street Address
21660 Copley Dr.
City
Diamond Bar
State
CA
ZipCode
91765
Phone Number
1-844-836-8200
Web Address
www.microingredients.com
Pharmacist Counseling Corner

Organic D-Mannose Powder by Micro Ingredients: Common Questions

Does Organic D-Mannose Powder by Micro Ingredients interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Organic D-Mannose Powder. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Organic D-Mannose Powder contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will D-mannose help prevent or treat a UTI?
The research suggests D-mannose is possibly ineffective for urinary tract infections, so it's not a reliable choice if that's why you're considering it. Talk with your doctor about proven options instead.
What are the side effects?
The most common are bloating, diarrhea, and nausea. Diarrhea risk goes up with higher doses — taking more than 200 mg/kg in a single dose is more likely to cause loose stools.
Is it safe to take long-term?
D-mannose is generally well tolerated short-term, but high-quality long-term safety data are limited, so caution is advised. If you're thinking of taking it regularly, check with your doctor or pharmacist first.
Can I take this while pregnant?
Safety data during pregnancy are not adequate, so it's best to avoid unless your doctor advises otherwise. Talk with your healthcare provider before using it.
Is it safe while breastfeeding?
Safety while breastfeeding is not well studied, so caution is advised. Speak with your doctor or pharmacist about whether it's right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic D-Mannose Powder is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic D-Mannose Powder label
Go deeper

The Full Monographs Behind Organic D-Mannose Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Organic D-Mannose Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

D-mannose 6 references
  1. Westphal V, Kjaergaard S, Davis JA, et al. Genetic and metabolic analysis of the first adult with congenital disorder of glycosylation type Ib: long-term outcome and effects of mannose supplementation. Mol Genet Metab 2001;73:77-85. PubMed
  2. Kranjcec B, Papes D, Altarac S. D-mannose powder for prophylaxis of recurrent urinary tract infections in women: a randomized clinical trial. World J Urol. 2014 Feb;32(1):79-84.
  3. de Lonlay P, Seta N. The clinical spectrum of phosphomannose isomerase deficiency, with an evaluation of mannose treatment for CDG-Ib. Biochim Biophys Acta. 2009;1792(9):841-3. PubMed
  4. Harms HK, Zimmer KP, Kurnik K, Bertele-Harms RM, Weidinger S, Reiter K. Oral mannose therapy persistently corrects the severe clinical symptoms and biochemical abnormalities of phosphomannose isomerase deficiency. Acta Paediatr. 2002;91(10):1065-72. DOI
  5. . Damen G, de Klerk H, Huijmans J, den Hollander J, Sinaasappel M. Gastrointestinal and other clinical manifestations in 17 children with congenital disorders of glycosylation type Ia, Ib, and Ic. J Pediatr Gastroenterol Nutr. 2004;38(3):282-7. DOI
  6. Lenger SM, Bradley MS, Thomas DA, Bertolet MH, Lowder JL, Sutcliffe S. D-mannose vs other agents for recurrent urinary tract infection prevention in adult women: a systematic review and meta-analysis. Am J Obstet Gynecol. 2020;223(2):265.e1-265.e13. PubMed

See these in context on the D-mannose monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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