Pancreatin Plus Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Pancreatin Plus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Pancreatin Plus is a dietary supplement by Douglas Laboratories with 3 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Pancreatin Plus by Douglas Laboratories
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Partial disclosure
Pancreatin Plus contains four active digestive enzymes. The protease breaks down proteins, the lipase breaks down fats, and the amylase breaks down carbohydrates — together they help your body digest food.
Pancreatin and pancreatin 8X are concentrated enzyme preparations from the pancreas that work the same way. The product also contains inactive ingredients: cellulose, gelatin, and vegetable stearate, which serve as the capsule and filler.
Does it work?
Couldn't assess
The evidence for these digestive enzymes is limited. For lipase specifically, we hold insufficient reliable evidence to rate its effectiveness for indigestion (dyspepsia) or inflammatory bowel disease (IBD).
The other active ingredients in this product don't have effectiveness ratings in our data, so we cannot say what the research shows about their benefit.
How safe is it?
Well-documented data
Protease and lipase are generally well tolerated by most adults, but some people report digestive upset or allergic reactions. There's a caution if you have serious digestive conditions — use only under medical guidance.
For pregnancy, there isn't enough safety data on supplemental protease or lipase to know either way; talk with your doctor or pharmacist before taking it if you're pregnant or breastfeeding. Proteolytic enzymes (proteases) can rarely trigger allergic reactions, especially with airborne exposure or in certain occupational settings, though this is uncommon.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. Before you start, review your exact medications with your pharmacist or the tool on this page to be certain.
The bottom line
Scorecard at a glancePartially disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.
This product is a digestive enzyme blend intended to support protein, fat, and carbohydrate digestion. If you have serious digestive or pancreatic conditions, check with your doctor or pharmacist first.
No documented interactions exist for the ingredients we reviewed, but mention this supplement to your own healthcare provider before starting it, especially if you take other medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 26, 2012.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Pancreatin Plus, straight from the product label.
| Brand | Douglas Laboratories |
|---|---|
| Barcode (UPC) | 310539017630 |
| Net contents | 250 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Apr 26, 2012 |
| DSLD ID | 8086 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Pancreatin Plus by Douglas Laboratories, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 0 NP | -- |
| Protease | 0 NP | -- |
| Lipase | 0 NP | -- |
| Pancreatin | 900 mg | -- |
| Pancreatin 8X | 900 mg | -- |
| Lipase 30 Material | 270 mg | -- |
Other ingredients: Cellulose, Gelatin, Vegetable Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
A Dietary Supplement
Formulation
This product contains NO yeast, wheat gluten, soy protein, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring.
Suggested/Recommended/Usage/Directions
Suggested Usage: As a dietary supplement, adults take as directed by healthcare professional.
Precautions
KEEP OUT OF REACH OF CHILDREN.
Tamper resistant package, do not use if outer seal is missing.
Storage
For optimal storage conditions, store in a cool, dry place. (59°-77°F/15°-25°C) (35-65% relative humidity)
General
Formula #7051
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Pancreatin Plus by Douglas Laboratories label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Pancreatin Plus by Douglas Laboratories
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container125 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Other (inactive) ingredients: Cellulose, Gelatin, Vegetable Stearate. These complete the product’s ingredient list but are not active constituents.
Pancreatin Plus by Douglas Laboratories Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Pancreatin Plus. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Pancreatin Plus, from the product label.
Douglas Laboratories
See all Douglas Laboratories products- Name
- Douglas Laboratories
- Street Address
- 600 Boyce Road
- City
- Pittsburgh
- State
- PA
- ZipCode
- 15205
- Web Address
- www.douglaslabs.com
Pancreatin Plus by Douglas Laboratories: Common Questions
Does Pancreatin Plus by Douglas Laboratories interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does each enzyme in Pancreatin Plus do?
Can I take Pancreatin Plus if I'm pregnant?
Are there any common side effects?
Does this product have fillers?
Is there evidence this works for indigestion?
Should I use this if I have a serious digestive condition?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Pancreatin Plus is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Pancreatin Plus’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Proteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monographLipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph →Sources & How We Checked
Pancreatin Plus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC