Pantothenic Acid 500 mg Ingredients & Drug Interactions
by GNC
What is this page for?
First and foremost: checking Pantothenic Acid 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Pantothenic Acid 500 mg is a dietary supplement by GNC with 1 active ingredient. Its ingredients are commonly taken for general nutrition and energy, skin and hair health, acne (topical and oral).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Pantothenic Acid 500 mg by GNC
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: pantothenic acid (vitamin B5) at 500 mg per capsule. Pantothenic acid is a B vitamin your body uses to break down food and produce energy, and it plays a role in making certain hormones and cholesterol.
The capsule also contains inactive ingredients — gelatin, cellulose, and whole brown rice powder — which help form and fill out the capsule.
Does it work?
Strong evidence
Pantothenic acid is effective for treating pantothenic acid deficiency, which is rare in people eating a typical diet. For radiation dermatitis (skin damage from radiation therapy), the evidence suggests it's likely ineffective.
For allergic rhinitis (hay fever), alopecia areata (patchy hair loss), and alcoholism, we don't hold enough reliable evidence to rate whether it works.
How safe is it?
Well-documented data
Orally, pantothenic acid is generally well tolerated at typical supplement doses. A small number of people have reported diarrhea.
The safety data advises you to check with your doctor before taking high-dose supplements — normal dietary amounts and prenatal-vitamin amounts are fine. During pregnancy and breastfeeding, the amounts found in food and prenatal vitamins are considered likely safe.
Again, discuss high-dose use with your doctor or pharmacist first.
Meds to double-check
No known interactions
No interactions are documented for pantothenic acid in our data. That doesn't mean none could occur — just that we have no evidence of them.
Check with your own pharmacist or doctor before starting, especially if you take multiple medications.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
This product is a straightforward pantothenic acid supplement that works for treating B5 deficiency and is generally well tolerated. If you're thinking about taking it for another reason — like hair loss or allergies — talk with your doctor or pharmacist first, since we don't have strong evidence it helps with those.
Check your medications using the tool on this page, and let your own healthcare provider know you're considering it.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Pantothenic Acid 500 mg, straight from the product label.
| Brand | GNC |
|---|---|
| Barcode (UPC) | 048107121563 |
| Net contents | 100 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 25, 2017 |
| DSLD ID | 74693 |
| Product type | Vitamin |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Pantothenic Acid 500 mg by GNC, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Pantothenic Acid | 500 mg | 5000% |
Other ingredients: Gelatin, Cellulose, whole Brown Rice powder
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Actual size
Required for energy metabolism
Potency verified by GNC proccedure #5118. Conforms to USP <2091> for weight. Meets USP <2040> for disintegration.
FDA Statement of Identity
Dietary Supplement
General
CODE 100413 ARG
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take one capsule daily.
Formulation
No sugar, no artificial colors, no artificial flavors, sodium free, no wheat, gluten free, no corn, no soy, no dairy, yeast free.
Precautions
Keep out of reach of children.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Pantothenic Acid 500 mg by GNC label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Pantothenic Acid 500 mg by GNC
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Pantothenic Acid
No knowninteractions
Pantothenic acid is vitamin B5, an essential nutrient your body uses to turn food into energy. True deficiency is very rare because it is found in nea...
Pantothenic Acid monograph & interactionsOther (inactive) ingredients: Gelatin, Cellulose, Whole Brown Rice powder. These complete the product’s ingredient list but are not active constituents.
Pantothenic Acid 500 mg by GNC Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Pantothenic Acid 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Pantothenic Acid 500 mg, from the product label.
GNC
See all GNC products- Name
- General Nutrition Corporation
- City
- Pittsburgh
- State
- PA
- ZipCode
- 15222
- Phone Number
- 1-888-462-2548
- Web Address
- www.gnc.com
Pantothenic Acid 500 mg by GNC: Common Questions
Does Pantothenic Acid 500 mg by GNC interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is pantothenic acid the same as vitamin B5?
Can I take this while pregnant or breastfeeding?
Will this help my hair loss?
What side effects should I watch for?
What does this product actually treat?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Pantothenic Acid 500 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Pantothenic Acid 500 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Pantothenic Acid 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 11 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Pantothenic Acid 11 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
- Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
- Schmuth, M., Wimmer, M. A., Hofer, S., Sztankay, A., Weinlich, G., Linder, D. M., Elias, P. M., Fritsch, P. O., and Fritsch, E. Topical corticosteroid therapy for acute radiation dermatitis: a prospective, randomized, double-blind study. Br.J.Dermatol. 2 PubMed
- Schreck, U., Paulsen, F., Bamberg, M., and Budach, W. Intraindividual comparison of two different skin care conceptions in patients undergoing radiotherapy of the head-and-neck region. Creme or powder? Strahlenther.Onkol. 2002;178(6):321-329. PubMed
- Herbst, R. A., Uter, W., Pirker, C., Geier, J., and Frosch, P. J. Allergic and non-allergic periorbital dermatitis: patch test results of the Information Network of the Departments of Dermatology during a 5-year period. Contact Dermatitis 2004;51(1):13-1 PubMed
- Champault, G. and Patel, J. C. [Treatment of constipation with Bepanthene]. Med.Chir Dig. 1977;6(1):57-59.
- Scott LN, Fiume M, Bergfeld WF, et al. Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics. Int J Toxicol 2022;41(3_suppl):77-128. PubMed
- Han J, Warshaw EM. Allergic Contact Dermatitis to Panthenol in "Hypoallergenic" Products. Dermatitis 2023;34(1):62-63. PubMed
- Blanchard G, Kerre S, Walker A, et al. Allergic contact dermatitis from pantolactone and dexpanthenol in wound healing creams. Contact Dermatitis 2022;87(5):468-471. PubMed
- Peltier E, Trapp S, de Salvo R, et al. A new dexpanthenol-containing liquid cleanser for atopic-prone skin: Results from two prospective clinical studies evaluating cutaneous tolerability, moisturization potential, and effects on barrier function. J Cosme PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC