Major interaction on record — check this product against your medications before combining. Based on 10 of 11 ingredients. Check your meds →
Dietary supplement

Peaceful Sleep Ingredients & Drug Interactions

by TriVita

Peaceful Sleep label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Peaceful Sleep against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Peaceful Sleep is a dietary supplement by TriVita with 11 active ingredients. Its ingredients are commonly taken for high cholesterol, vitamin b3 deficiency (pellagra), heart health support.Based on those ingredients, 868 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Niacin, Magnesium, Vitamin B6. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Peaceful Sleep by TriVita

Ask about any prescription or over-the-counter medication and we check it for interactions with Peaceful Sleep by TriVita — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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Computed from our clinical databases

HelloPharmacist Scorecard of Peaceful Sleep by TriVita

Four independent checks of what is known — a summary of the available information, not a grade of the product itself.

Evidence for Intended Use
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The stated purpose hasn't been mapped to our evidence data yet.

Why this rating?
  • We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Ingredient Transparency
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 11 of its 11 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.
Known Interaction Concern
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 8 of the 10 matched ingredients can interact with medications — Calcium, Niacin, Vitamin B12, Vitamin B6, Riboflavin, among others.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications; lithium; Parkinson's medications.
  • For scale: 869 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Safety Information
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 10 of the 10 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 10 of 10.
  • General safety write-ups exist for 10 of 10.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Assessment coverage: 10 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 24, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Peaceful Sleep, straight from the product label.

Brand TriVita
Net contents 60 Capsule(s)
Market status Off market
Date entered into DSLD Aug 24, 2012
DSLD ID 11489
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Peaceful Sleep by TriVita, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
6 Capsule(s)
Servings per container
30
IngredientAmount% DV
Niacin2 mg10%
Vitamin B60.25 mg13%
Folic Acid50 mcg13%
Vitamin B125 mcg83%
Thiamine1 mg67%
Biotin1000 mcg333%
Pantothenic Acid69 mg690%
Calcium5.25 mg1%
Magnesium150 mg38%
Riboflavin0.25 mg15%
Proprietary blend885 mg--

Other ingredients: Gelatin, Magnesium Stearate, Corn Starch, Silicon Dioxide, Rice Flour

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Adults, take 2 to 6 capsules 30 minutes before bedtime or as recommended by a healthcare provider. Continue daily use until a normal sleep pattern is established, then take as needed.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Children, women who are pregnant or nursing, and all individuals allergic to any foods or ingredients should consult their healthcare provider before using this product. You should not stop taking any medication without first consulting with a healthcare provider.

Do not use if seal is broken.

Caution: Do not take prior to driving or operating machinery.

Seals/Symbols

PHYSICIAN APPROVED FORMULA

TRIVITA(R) experience wellness

Storage

Store in a cool, dry place.

General

Item 30320 L1005-01

Brand IP Statement(s)

(C)2010 TriVita, Inc

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Peaceful Sleep by TriVita label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Peaceful Sleep label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Peaceful Sleep by TriVita

These are the 11 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Niacin

Interacts with
727 drugs
2 mg per serving

Niacin (vitamin B3) is an essential nutrient your body needs for energy and metabolism, and deficiency is uncommon in most developed countries. Prescr...

Niacin monograph & interactions

Vitamin B6

Interacts with
210 drugs
0.25 mg per serving Form: Pyridoxine Hydrochloride

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vitamin B6 monograph & interactions

Folic Acid

Interacts with
40 drugs
50 mcg per serving

Folic acid is the man-made form of vitamin B9 and is one of the most well-studied supplements, especially for preventing serious birth defects when ta...

Folic Acid monograph & interactions

Vitamin B12

Interacts with
20 drugs
5 mcg per serving Form: Cyanocobalamin

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very h...

Vitamin B12 monograph & interactions

Thiamine

Interacts with
3 drugs
1 mg per serving Form: Thiamine Hydrochloride

Thiamine (vitamin B1) is an essential nutrient your body needs to turn food into energy and to keep your nerves and heart healthy. Most people get eno...

Thiamine monograph & interactions

Biotin

No known
interactions
1000 mcg per serving

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Biotin monograph & interactions

Pantothenic Acid

No known
interactions
69 mg per serving Form: D-Calcium Pantothenate

Pantothenic acid is vitamin B5, an essential nutrient your body uses to turn food into energy. True deficiency is very rare because it is found in nea...

Pantothenic Acid monograph & interactions

Calcium

Interacts with
168 drugs
5.25 mg per serving Form: Calcium D-Pantothenate

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet f...

Calcium monograph & interactions

Magnesium

Interacts with
295 drugs
150 mg per serving Form: Magnesium Sulfate

Magnesium is an essential mineral your body needs for muscles, nerves, blood pressure, and many other functions, and supplements are useful for preven...

Magnesium monograph & interactions

Riboflavin

Interacts with
20 drugs
0.25 mg per serving Form: riboflavin-5-phosphate sodium

Riboflavin (vitamin B2) is an essential nutrient your body needs to turn food into energy and to keep skin, eyes, and nerves healthy. It is generally...

Riboflavin monograph & interactions

Proprietary blend

885 mg per serving Form: 5-HTP, Acetylcholine 30X, Anemarrhena Asphodeloides, Dopamine 30X, GABA, Glycyrrhiza Glabra, Histamine 30X, Inositol, L-Glutamine, Ligusticum Sinense (root) Extract, Passiflora Incarnata (flower) Extract, Poria Cocos, TMG, Zizyphus Spinosa

Other (inactive) ingredients: Gelatin, Magnesium Stearate, Corn Starch, Silicon Dioxide, Rice Flour. These complete the product’s ingredient list but are not active constituents.

Interaction report

Peaceful Sleep by TriVita Drug Interactions

Peaceful Sleep contains 11 ingredients, and 8 of them have known drug interactions. Altogether they interact with 868 medications. Here’s the picture, then you can look up your own drug.

Want to check YOUR meds against Peaceful Sleep?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
868Drugs
13 Major 851 Moderate 4 Minor

Ingredients driving the most interactions

Niacin 727
Magnesium 295
Vitamin B6 210
Calcium 168
Folic Acid 40

Individual Drug Interactions

The ingredients in Peaceful Sleep interact with 868 drugs. Click any drug to see the details.

8 of the 11 ingredients in Peaceful Sleep interact with drugs. Each result below shows which ingredient is responsible. Niacin Magnesium Vitamin B6 Calcium Folic Acid Vitamin B12 Riboflavin Thiamine