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Dietary supplement

Performance Vision Ingredients & Drug Interactions

by Nutra Sport

Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Performance Vision is a dietary supplement by Nutra Sport with 3 active ingredients. Its ingredients are commonly taken for antioxidant support, heart health, brain and memory health.Based on those ingredients, 277 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bilberry fruit concentrate, Blueberry fruit concentrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Performance Vision by Nutra Sport

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 3 active ingredients.
  • “BIL/MAX/BLU-MAX 2:1 Blend” is a proprietary blend — the label gives one combined amount (500 mg) without saying how much of each component you get.

Performance Vision contains 3 active ingredients: blueberry fruit concentrate, bilberry fruit concentrate, and Lutemax 2020 (a lutein source). The product also includes inactive ingredients — a capsule shell and magnesium stearate (a binder).

Blueberry and bilberry are both berry extracts traditionally used to support eye and overall health. Lutein is a naturally occurring plant pigment found in leafy greens and other foods, often included in vision supplements.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Eye health support.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Central serous retinopathy, Choroideremia, Diabetic retinopathy — and 4 related terms.
  • The strongest evidence on file: Lutein is rated "Possibly Effective" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Lutein is rated "Possibly Effective" for Cataracts.
  • Also on file: Bilberry is rated "Insufficient Reliable Evidence To Rate" for Age-related macular degeneration (AMD), Cataracts, Diabetic retinopathy, Dry eye, and more.

The evidence for this product's ingredients is mixed. Lutein is possibly effective for age-related macular degeneration (AMD) and cataracts — two common eye conditions.

Blueberry's evidence is limited: hypertension is rated possibly ineffective, while age-related cognitive decline, anxiety, athletic performance, and cholesterol don't have enough reliable evidence to rate. Bilberry similarly shows possibly ineffective evidence for night vision, with insufficient evidence for AMD, age-related cognitive decline, atherosclerosis, cholesterol, and chronic vein issues.

Bottom line: lutein may help with certain age-related eye problems, but the blueberry and bilberry components lack solid evidence for their intended uses.

The evidence, ingredient by ingredient Blueberry Bilberry Lutein

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

All three ingredients are generally well tolerated. Blueberry is generally safe as food; concentrated supplements in pregnancy haven't been well studied, and high-dose extracts while breastfeeding are unknown — the safety rating for pregnancy and lactation is Likely Safe overall.

Bilberry fruit extract is typically well tolerated with mild side effects like dark stools, gas, and GI discomfort possible. Bilberry also carries a caution for pregnancy and lactation because concentrated supplements lack solid safety data, though the overall rating is Likely Safe.

Lutein is generally safe at typical doses (up to 20 mg daily caused no adverse effects in trials). The most common side effect with freeze-dried blueberries is GI upset — one trial saw 26% of participants drop out in the first week due to constipation, diarrhea, nausea, or vomiting.

Side effects, ingredient by ingredient Blueberry Bilberry Lutein

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Bilberry, Blueberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 277 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take blood thinners (anticoagulants or antiplatelet drugs like warfarin or aspirin), diabetes medications, drugs processed by the CYP2E1 liver enzyme, erlotinib (a cancer medication), flurbiprofen (an anti-inflammatory), or buspirone (an anxiety medication), check your exact drugs with the search tool before taking this product. Bilberry carries Moderate-severity interactions with blood thinners and diabetes drugs; blueberry carries Minor interactions with several of these categories.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product combines lutein (which has some evidence for AMD and cataracts) with blueberry and bilberry extracts (with limited or absent evidence). It's potentially worth considering if you're interested in lutein for age-related eye health, but don't expect strong proof for the berries.

If you take blood thinners, diabetes medications, or cancer drugs, check with your pharmacist before starting — the bilberry and blueberry components carry documented interactions with these drug types.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Performance Vision, straight from the product label.

Brand Nutra Sport
Net contents 30 Vegan Capsule(s)
Market status On market
Date entered into DSLD Nov 22, 2024
DSLD ID 319232
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Performance Vision by Nutra Sport, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
IngredientAmount% DV
Blueberry fruit concentrate0 NP--
Bilberry fruit concentrate0 NP--
BIL/MAX/BLU-MAX 2:1 Blend500 mg--
Lutemax 202010 mg--

Other ingredients: Capsule, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take one capsule up to two times daily with food.

Formulation

Our powerful Performance Vision supports eye health with a proprietary low heat process. Our Bio-Shield Technology concentrates, protects, and controls the release of nutrients that are easily damaged during processing or in the stomach.

We guarantee our supplements for potency and purity

Double Verified GF Gluten Free Copyright No GMO Ingredients Copyright SGS verified the process for manufacturing this product with no GMO ingredients. www.sgs.com/no-gmo

Bio-Shield Technology

Contains no artificial colors, flavors or preservatives; no wheat, gluten, milk, eggs, peanuts, tree nuts, soy, crustacean shellfish or fish.

Formula

Lutein and zeaxanthin are carotenoids that promote eye health. Bilberries, native to northern Europe, are combined with blueberry concentrates in this full spectrum formula. Both are rich in anthocyanin compounds and other nutrients to support healthy eyes.

Lutemax 2020 Lutein with Bilberry & Blueberry Concentrates

Brand IP Statement(s)

BIL-MAX and BLU-MAX are registered trademarks of Cape Cod Biolab Corp. Lutemax 2020 Lutein & Zeaxanthin Lutemax 2020 trademarks belongs to OmniActive Health Technologies Ltd.

Storage

Store in a cool, dry place.

Precautions

To report a serious adverse event, call 1-888-710-0006

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

Double Verified GF Gluten Free Copyright No GMO Ingredients Copyright SGS verified the process for manufacturing this product with no GMO ingredients. www.sgs.com/no-gmo

FDA Statement of Identity

Dietary Supplement

See for yourself

Performance Vision by Nutra Sport label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Performance Vision by Nutra Sport

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

BIL/MAX/BLU-MAX 2:1 Blend

500 mg per serving

Lutemax 2020

No known
interactions
10 mg per serving Form: Lutein

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...

Lutemax 2020 monograph & interactions

Other (inactive) ingredients: Capsule, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Performance Vision by Nutra Sport Drug Interactions

Want to check YOUR meds against Performance Vision?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
277Drugs
275 Moderate 2 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Performance Vision with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Bilberry fruit concentrate4 drug types · 275 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro, animal, and clinical research suggest that anthocyanidin extracts from bilberry can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, bilberry leaf or fruit extract may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that bilberry leaf extract might have blood glucose-lowering activity. Also, one small clinical trial in patients with type 2 diabetes shows that taking bilberry fruit extract 470 mg as a single dose prior to an oral glucose tolerance test lowers plasma glucose levels when compared with placebo.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Animal research shows that exposure to small concentrations of bilberry extract in drinking water for around one month increased CYP2E1 activity by 31%. However, exposure over a 2-month period did not increase CYP2E1 activity. This effect has not been reported in humans.

Likelihood Possible Evidence D
Erlotinib (Tarceva)

Theoretically, bilberry fruit extract might reduce the efficacy of erlotinib.
In vitro research suggests that bilberry fruit extract and its constituents, delphinidin and delphinidin-3-O-glucoside, inhibit the activity of erlotinib. This interaction has not been reported in humans.

Likelihood Possible Evidence D

Blueberry fruit concentrate3 drug types · 88 drugs

Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggests that blueberry and/or blueberry leaf extracts can lower blood glucose levels.

Likelihood Unlikely Evidence D
Buspirone (Buspar)

Theoretically, blueberry juice might increase blood levels of buspirone.
In vitro research shows that blueberry juice can inhibit the metabolism of buspirone, possibly by inhibiting cytochrome P450 3A (CYP3A) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking buspirone hydrochloride 10 mg does not significantly affect the concentration or clearance of buspirone.

Likelihood Unlikely Evidence B
Flurbiprofen (Ansaid, Others)

Theoretically, blueberry juice might increase blood levels of flurbiprofen.
In vitro research shows that blueberry juice can inhibit the metabolism of flurbiprofen, possibly by inhibiting cytochrome P450 2C9 (CYP2C9) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking flurbiprofen 100 mg does not significantly affect the concentration or clearance of flurbiprofen.

Likelihood Unlikely Evidence B
The maker

Brand information

Manufacturer and brand details for Performance Vision, from the product label.

Nutra Sport

See all Nutra Sport products
Name
E-NutritionStore.com
City
Elkridge
State
MD
ZipCode
21075
Phone Number
443-483-3340
Web Address
E-NutritionStore.com
Pharmacist Counseling Corner

Performance Vision by Nutra Sport: Common Questions

Does Performance Vision by Nutra Sport interact with any medications?
Yes. Based on its ingredients, Performance Vision has a known interaction with 277 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Performance Vision contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my vision?
Lutein, one of the three active ingredients, is possibly effective for age-related macular degeneration and cataracts — the vision problems most likely to benefit. The blueberry and bilberry extracts lack solid evidence for eye health. Talk to your eye doctor about whether lutein makes sense for your situation.
What are the side effects?
All three ingredients are generally well tolerated. The most common issue is gastrointestinal — constipation, diarrhea, nausea, gas, or discomfort. In one trial, 26% of people taking freeze-dried blueberries at high doses dropped out in the first week due to stomach complaints. You may also notice dark-colored or dark-greenish stools.
Is it safe in pregnancy or while breastfeeding?
All three ingredients carry an overall Likely Safe rating for pregnancy and lactation. However, the concentrated supplement forms in this product haven't been well studied during pregnancy or while breastfeeding — food amounts are different from what's in a capsule. Talk with your doctor or pharmacist if you're pregnant or nursing.
Can I take this if I'm on a blood thinner?
Bilberry, one of the ingredients, may theoretically increase bleeding risk with anticoagulants and antiplatelet drugs. Don't start this product without checking with your pharmacist or doctor first — they can review your exact medication.
Will this affect my diabetes medication?
Both blueberry and bilberry may theoretically lower blood sugar, raising the risk of low blood sugar (hypoglycemia) if you take diabetes medications. This is a Minor to Moderate concern depending on the ingredient. Check with your pharmacist or doctor before taking this supplement.
What's in the capsule besides the active ingredients?
The inactive ingredients are the capsule shell itself and magnesium stearate, a binder used to hold the formula together. There are no other fillers.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Performance Vision label
Sources

Sources & How We Checked

Performance Vision's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 23 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Blueberry 7 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem 2000;48:140-6.. PubMed
  3. Martineau, L. C., Couture, A., Spoor, D., Benhaddou-Andaloussi, A., Harris, C., Meddah, B., Leduc, C., Burt, A., Vuong, T., Mai, Le P., Prentki, M., Bennett, S. A., Arnason, J. T., and Haddad, P. S. Anti-diabetic properties of the Canadian lowbush bluebe
  4. Vuong, T., Martineau, L. C., Ramassamy, C., Matar, C., and Haddad, P. S. Fermented Canadian lowbush blueberry juice stimulates glucose uptake and AMP-activated protein kinase in insulin-sensitive cultured muscle cells and adipocytes. Can J Physiol Pharma
  5. Hanley MJ, Masse G, Harmatz JS, Cancalon PF, Dolnikowski GG, Court MH, Greenblatt DJ. Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. Br J Clin Pharmacol. 2013 Apr;75(4):1041-52. PubMed
  6. Basu A, Du M, Leyva MJ, et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr 2010;140(9):1582-7. PubMed
  7. Basu A, Feng D, Planinic P, Ebersole JL, Lyons TJ, Alexander JM. Dietary blueberry and soluble fiber supplementation reduces risk of gestational diabetes in women with obesity in a randomized controlled trial. J Nutr 2021;151(5):1128-38. PubMed

See these in context on the Blueberry monograph →

Bilberry 14 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Morazzoni P, Magistretti MJ. Activity of Myrtocyan, an anthosyanoside complex from Vaccinium myrtillus (VMA), on platelet aggregation and adhesiveness. Fitoterapia 1990;61:13-21.
  3. Erlund, I., Koli, R., Alfthan, G., Marniemi, J., Puukka, P., Mustonen, P., Mattila, P., and Jula, A. Favorable effects of berry consumption on platelet function, blood pressure, and HDL cholesterol. Am J Clin Nutr 2008;87(2):323-331. PubMed
  4. Hawrelak, J. A. and Myers, S. P. Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study. J Altern Complement Med 2010;16(10):1065-1071. PubMed
  5. Morazzoni P and Magistretti MJ. Effects of Vaccinium myrtillus anthocyanosides on prostacyclin-like activity in rat arterial issue. Fitoterapia 1986;57:11-14.
  6. Pulliero G, Montin S, Bettini V, and et al. Ex vivo study of the inhibitory effects of Vaccinium myrtillus anthocyanosides on human platelet aggregation. Fitoterapia 1989;60:69-75.
  7. Bottecchia D. Preliminary report on the inhibitory effect of vaccinium myrtillus anthocyanosides on platelet aggregation and clot retraction. Fitoterapia 1987;48:3-8.
  8. Fdez, M., Zaragoza, F., and Alvarez, P. In vitro platelet aggregation effects of anthocyanosides of vaccinium myrtilus L. Anales de la Real Academia de Farmacia 1983;49:79-90.
  9. Biedermann L, Mwinyi J, Scharl M, Frei P, Zeitz J, Kullak-Ublick GA, et al. Bilberry ingestion improves disease activity in mild to moderate ulcerative colitis-an open pilot study. 2013 May;7(4):271-9. PubMed
  10. Hoggard N, Cruickshank M, Moar KM, Bestwick C, Holst J, Russell W, et al. A single supplement of a standardized bilberry (Vaccinium myrtillus L.) extract (36% wet weight anthocyanins) modifies glycaemic response in individuals with type 2 diabetes control
  11. Aichinger G, Pahlke G, Nagel LJ, Berger W, Marko D. Bilberry extract, its major phenolic compounds, and soy isoflavone genistein antagonize the cytostatic drug erlotinib in human epithelial cells. Food Funct 2016;7(8):3628-36.
  12. Prokop J, Lněničková K, Cibicek N, et al. Effect of bilberry extract (Vaccinium myrtillus L.) on drug-metabolizing enzymes in rats. Food Chem Toxicol 2019;129:382-90. PubMed
  13. Chan SW, Chu TTW, Choi SW, Benzie IFF, Tomlinson B. Impact of short-term bilberry supplementation on glycemic control, cardiovascular disease risk factors, and antioxidant status in Chinese patients with type 2 diabetes. Phytother Res 2021. Online ahead o PubMed
  14. Bøhn SK, Myhrstad MCW, Thoresen M, et al. Bilberry/red grape juice decreases plasma biomarkers of inflammation and tissue damage in aged men with subjective memory impairment -a randomized clinical trial. BMC Nutr 2021;7(1):75. PubMed

See these in context on the Bilberry monograph →

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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