No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Perilla Ingredients & Drug Interactions

by GHC Global Healing Center

Perilla label
See full label image
Liquid Category: Botanical
No known interaction
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Perilla against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Perilla is a dietary supplement by GHC Global Healing Center with 1 active ingredient. Its ingredients are commonly taken for seasonal and food allergies, asthma and airway inflammation, atopic dermatitis (eczema).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

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HelloPharmacist Scorecard of Perilla by GHC Global Healing Center

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Certified Organic Perilla frutescens, a plant also known as perilla mint or shiso. The liquid is made with kosher certified vegetable glycerin and purified water as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Perilla product and its label doesn't state a use — see Perilla's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold for perilla doesn't establish its effectiveness for any of the uses it's marketed for—age-related cognitive decline, hay fever, asthma, osteoporosis, cancer, or headache. All six uses carry a rating of insufficient reliable evidence to rate, meaning there's not enough solid research data to say whether it works or doesn't work for these purposes.

The evidence, ingredient by ingredient Perilla

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Perilla is generally well tolerated as a food, but supplement-strength products haven't been studied much, so we can't say the same for concentrated doses used therapeutically. The most serious concern is anaphylaxis (a severe allergic reaction)—a rare but documented risk, especially if you eat perilla seeds or are exposed to roasted perilla smoke.

Dermatitis (skin irritation) can occur with topical use. There isn't enough safety data to know whether perilla is safe during pregnancy or breastfeeding at medicinal doses, so the safety data advises against use at those times.

Talk with your doctor or pharmacist about whether this product is right for you if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Perilla

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. However, because perilla as a supplement hasn't been thoroughly studied, mention this product to your own doctor or pharmacist if you're on any regular medications.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Perilla is generally well tolerated as a food, but supplement-strength products are not well studied, and we don't have solid evidence that it works for the conditions it's marketed for. If you have a history of allergies or are pregnant or breastfeeding, talk with your doctor or pharmacist before taking it.

Anyone taking medications should check with their own healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 26, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Perilla, straight from the product label.

Brand GHC Global Healing Center
Barcode (UPC) 718122405152
Net contents 2 fl. Oz.; 59.2 mL
Market status On market
Date entered into DSLD Feb 26, 2014
DSLD ID 30391
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Perilla by GHC Global Healing Center, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.25 tsp
Maximum serving Sizes:
0.25 tsp
Servings per container
48
UPC/BARCODE
718122405152
IngredientAmount% DV
Certified Organic Perilla frutescens1.23 mL--

Other ingredients: Kosher Certified Vegetable glycerin, purified water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Herb handpicked and dried from: www.earthharmonyorganics.com

Lot #: Batch:

Formula

(Perilla frutescens) Liquid Spagyrex(TM) Herbal Formula

Suggested/Recommended/Usage/Directions

SUGGESTED USE: Take 1 serving, approximately 2 droppers, in the morning and 1 serving in the afternoon before meals.

Precautions

WARNING: KEEP OUT OF REACH OF CHILDREN.

CONSULT YOUR HEALTHCARE PROVIDER BEFORE TAKING IF PREGNANT OR NURSING, OR FOR ANY ADDITIONAL CONCERNS.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

EARTH HARMONY ORGANIC

GMO -V vegan -MADE IN THE USA -NO ANIMAL TESTING -GLUTEN FREE

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Perilla by GHC Global Healing Center label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Perilla label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Perilla by GHC Global Healing Center

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.25 tsp Dosage formLiquid Servings per container48 Amounts shown are per serving.

Certified Organic Perilla frutescens

No known
interactions
1.23 mL per serving

Perilla is an Asian mint-family plant used in cooking and traditional medicine, mainly for allergy, breathing, and digestive complaints. Most human ev...

Certified Organic Perilla frutescens monograph & interactions

Other (inactive) ingredients: Kosher Certified Vegetable glycerin, Purified water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Perilla by GHC Global Healing Center Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Perilla. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Perilla, from the product label.

GHC Global Healing Center

See all GHC Global Healing Center products
Web Address
www.globalhealingcenter.com
Pharmacist Counseling Corner

Perilla by GHC Global Healing Center: Common Questions

Does Perilla by GHC Global Healing Center interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Perilla. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Perilla contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I have a food allergy?
If you have a history of allergies, be cautious—perilla can trigger anaphylaxis (a severe allergic reaction), a rare but documented risk. Talk with your doctor or pharmacist about whether this product is safe for you.
Is perilla safe during pregnancy or breastfeeding?
There isn't enough safety data to know either way at medicinal doses, so the safety data advises against use during pregnancy and breastfeeding. Talk with your doctor or pharmacist for personalized advice if you're pregnant, planning pregnancy, or breastfeeding.
What are the side effects?
Taken by mouth, perilla is generally well tolerated with no common side effects reported. The main serious risk is anaphylaxis (a severe allergic reaction), which is rare. If applied to skin, dermatitis (irritation) can occur.
Does perilla actually work for hay fever or asthma?
The evidence we hold doesn't establish whether perilla works for hay fever, asthma, or any of the other conditions it's marketed for. All of them are rated as having insufficient reliable evidence.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Perilla is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Perilla label
Go deeper

The Full Monographs Behind Perilla’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Perilla

Perilla is an Asian mint-family plant used in cooking and traditional medicine, mainly for allergy, breathing, and digestive complaints. Most human evidence is limited or preliminary, so it...

Read the full Perilla monograph →
Sources

Sources & How We Checked

Perilla's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Perilla 4 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Kanzaki, T. and Kimura, S. Occupational allergic contact dermatitis from Perilla frutescens (shiso). Contact Dermatitis 1992;26(1):55-56.
  3. Yu H, Qiu JF, Ma LJ, Hu YJ, Li P, Wan JB. Phytochemical and phytopharmacological review of Perilla frutescens L. (Labiatae), a traditional edible-medicinal herb in China. Food Chem Toxicol 2017;108(Pt B):375-91. PubMed
  4. Jeong K, Lee SY, Jeon SA, et al. Clinical and immunological characterization of perilla seed allergy in children. J Investig Allergol Clin Immunol 2021. PubMed

See these in context on the Perilla monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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