No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Perilla Extract Ingredients & Drug Interactions

by Pure Encapsulations

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Perilla Extract is a dietary supplement by Pure Encapsulations with 1 active ingredient. Its ingredients are commonly taken for seasonal and food allergies, asthma and airway inflammation, atopic dermatitis (eczema).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Perilla Extract by Pure Encapsulations

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: perilla seed extract. Perilla is a plant used traditionally in Asian cuisines and herbal medicine.

The extract is delivered in a capsule with cellulose and water as inactive ingredients.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: respiratory and allergic response support.
  • We looked for evidence on: Allergic rhinitis (hay fever), Asthma, atopic dermatitis, food allergies.
  • The closest evidence on file: Perilla is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever) (Natural Medicines).
  • Also on file: Perilla is rated "Insufficient Reliable Evidence To Rate" for Asthma.

The evidence for perilla extract isn't established in the data we hold. The ingredient carries insufficient reliable evidence ratings for age-related cognitive decline, allergic rhinitis (hay fever), asthma, osteoporosis, cancer, and headache.

In other words, we don't have strong study data showing it works for these uses.

The evidence, ingredient by ingredient Perilla

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Perilla seed extract is generally well tolerated when taken by mouth, but supplement-strength products haven't been studied thoroughly. The most common side effect from topical use is dermatitis (skin irritation).

Rarely, people have reported anaphylaxis (a severe allergic reaction) after consuming perilla seeds — some research suggests a compound called oleosin may be responsible for perilla allergies. Additionally, occupational asthma has been reported from inhaling smoke from roasted perilla seeds.

There isn't enough safety data to know whether medicinal amounts are safe during pregnancy or while breastfeeding. Talk with your doctor or pharmacist about whether this product is right for you if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Perilla

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for perilla seed extract in our data. That's not a guarantee none exist — it simply means the monograph we hold doesn't flag any.

Check your exact medications with the interaction tool on this page, or ask your doctor or pharmacist before you begin.

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Perilla Extract may appeal to you if you're exploring traditional herbal options, but the evidence that it works for any specific condition isn't established in our data. Be especially cautious if you have a tree nut or seed allergy, given the anaphylaxis reports.

Talk it over with your doctor or pharmacist before starting, particularly if you're pregnant, breastfeeding, or have asthma.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Perilla Extract, straight from the product label.

Brand Pure Encapsulations
Barcode (UPC) 766298022208
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Dec 14, 2023
DSLD ID 299734
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Perilla Extract by Pure Encapsulations, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
766298022208
IngredientAmount% DV
Perilla Seed Extract150 mg--

Other ingredients: Cellulose, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Recommendations: As a dietary supplement, take 1 capsule, 1-2 times daily, between meals, or as directed by a health professional.

Precautions

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Keep out of the reach of children.

Use only if safety seal is intact.

General Statements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our hypoallergenic supplements

Seals/Symbols

GFCO.org (Gluten-Free Certification Organization)

Formulation

Certified Gluten-Free by the Gluten-Free Certified Organization www.gluten.org Gluten-Free, Non-GMO & Hypoallergenic

Gluten-Free, Non-GMO & Hypoallergenic

Formula

PureResponse Formula; Perilla seed extract to support healthy modulation of Th2 cytokines and mucosal health

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Perilla Extract by Pure Encapsulations label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Perilla Extract by Pure Encapsulations

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Perilla Seed Extract

No known
interactions
150 mg per serving Form: Perilla frutescens Seed Extract

Perilla is an Asian mint-family plant used in cooking and traditional medicine, mainly for allergy, breathing, and digestive complaints. Most human ev...

Perilla Seed Extract monograph & interactions

Other (inactive) ingredients: Cellulose, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Perilla Extract by Pure Encapsulations Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Perilla Extract. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Perilla Extract, from the product label.

Pure Encapsulations

See all Pure Encapsulations products
Name
Pure Encapsulations
Street Address
490 Boston Post Road
City
Sudbury
State
MA
Phone Number
1-800-753-2277
Web Address
www.PureEncapsulations.com
Pharmacist Counseling Corner

Perilla Extract by Pure Encapsulations: Common Questions

Does Perilla Extract by Pure Encapsulations interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Perilla Extract. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Perilla Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety data to know whether medicinal amounts of perilla are safe during pregnancy or while breastfeeding. Talk with your doctor or pharmacist for personalized advice — they can help you weigh the risks and benefits for your situation.
What are the side effects?
Taken by mouth, perilla seems well tolerated overall. Rarely, people have reported anaphylaxis (a severe allergic reaction) after eating perilla seeds — a compound called oleosin may trigger this in sensitive people. If you have a tree nut or seed allergy, mention that to your doctor or pharmacist before taking this.
Does perilla actually work for what it claims?
The evidence isn't established in our data. This extract carries insufficient reliable evidence ratings for all the conditions it's marketed for — age-related cognitive decline, hay fever, asthma, osteoporosis, cancer, and headache. That means we don't have strong study data showing it works for these uses.
Is this supplement well studied?
Perilla is generally well tolerated as a food, but supplement-strength products haven't been well studied. That's an important difference — we know less about safety and effectiveness at the doses used in supplements like this one.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Perilla Extract is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Perilla Extract label
Go deeper

The Full Monographs Behind Perilla Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Perilla Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Perilla 4 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Kanzaki, T. and Kimura, S. Occupational allergic contact dermatitis from Perilla frutescens (shiso). Contact Dermatitis 1992;26(1):55-56.
  3. Yu H, Qiu JF, Ma LJ, Hu YJ, Li P, Wan JB. Phytochemical and phytopharmacological review of Perilla frutescens L. (Labiatae), a traditional edible-medicinal herb in China. Food Chem Toxicol 2017;108(Pt B):375-91. PubMed
  4. Jeong K, Lee SY, Jeon SA, et al. Clinical and immunological characterization of perilla seed allergy in children. J Investig Allergol Clin Immunol 2021. PubMed

See these in context on the Perilla monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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