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Dietary supplement

Pharmaceutical Grade AjiPure Glycine Ingredients & Drug Interactions

by Swanson Ultra

Pharmaceutical Grade AjiPure Glycine label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pharmaceutical Grade AjiPure Glycine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pharmaceutical Grade AjiPure Glycine is a dietary supplement by Swanson Ultra with 1 active ingredient. Its ingredients are commonly taken for sleep quality and insomnia, relaxation, cognitive function.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Glycine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Pharmaceutical Grade AjiPure Glycine by Swanson Ultra

Ask about any prescription or over-the-counter medication and we check it for interactions with Pharmaceutical Grade AjiPure Glycine by Swanson Ultra — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Pharmaceutical Grade AjiPure Glycine by Swanson Ultra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: glycine, a simple amino acid. Glycine is supplied as a pharmaceutical-grade powder, with no inactive fillers or other ingredients listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Glycine's overall clinical evidence instead.

Moderate

Some clinical evidence supports Glycine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Schizophrenia — rated "Possibly Effective" (Natural Medicines).

Glycine is rated possibly effective for schizophrenia based on available evidence. For other uses—including 3-phosphoglycerate dehydrogenase (3-PGDH) deficiency, ADHD, benign prostatic hyperplasia (BPH), and cystic fibrosis—there isn't enough reliable evidence in our data to establish how well it works.

The evidence, ingredient by ingredient Glycine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Glycine is generally well tolerated at typical doses, but long-term safety data are limited. Mild sedation, irritability, insomnia, fatigue, memory impairment, headache, and sensory impairment have been reported rarely, though it's unclear whether glycine caused them.

Soft stools, nausea, vomiting, upper gastrointestinal discomfort, and dry mouth have also been reported rarely. Any symptoms that do occur tend to resolve quickly once you stop taking it.

There isn't enough reliable safety data during pregnancy and lactation, so the data we hold advises caution in both. Talk with your doctor or pharmacist before using this product if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Glycine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Glycine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take clozapine (Clozaril) for schizophrenia, check with your doctor or pharmacist before using this product—glycine may decrease its effectiveness and worsen symptoms.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Glycine may help with schizophrenia symptoms, though the evidence is limited. The main concern is a potential interaction with clozapine that could worsen schizophrenia symptoms.

If you take clozapine or any other medication, check with your doctor or pharmacist before starting this product. Long-term safety data are sparse, so discuss it with your healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pharmaceutical Grade AjiPure Glycine, straight from the product label.

Brand Swanson Ultra
Barcode (UPC) 087614025155
Net contents 8 Oz(s); 227 Gram(s)
Market status On market
Date entered into DSLD Jul 25, 2018
DSLD ID 177876
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pharmaceutical Grade AjiPure Glycine by Swanson Ultra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Gram(s)
Maximum serving Sizes:
1 Gram(s)
Servings per container
227
UPC/BARCODE
087614025155
IngredientAmount% DV
Glycine1 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

The most advanced nutrition technology Powder

To reorder, call toll free 1-800-437-4148 or visit our website at www.swansonvitamins.com

Note: Settling may occur.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

AjiPure Amino Acids Guaranteed purity & potency

Brand IP Statement(s)

AjiPure and the AjiPure logo are registered trademarks of Ajinomoto, Inc.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, mix one scoop (1 g) in your favorite beverage. For best results, take on an empty stomach. Scoop included.

Precautions

Do not use if seal is broken.

Keep out of reach of children.

Storage

Store in a cool, dry place.

General

SWU515 Rev 0 06 14 17

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pharmaceutical Grade AjiPure Glycine by Swanson Ultra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pharmaceutical Grade AjiPure Glycine label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pharmaceutical Grade AjiPure Glycine by Swanson Ultra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Gram(s) Dosage formPowder Servings per container227 Amounts shown are per serving.

Glycine

Interacts with
1 drug
1 Gram(s) per serving

Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep q...

Glycine monograph & interactions
Interaction report

Pharmaceutical Grade AjiPure Glycine by Swanson Ultra Drug Interactions

Want to check YOUR meds against Pharmaceutical Grade AjiPure Glycine?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Glycine 1

Individual Drug Interactions

The ingredients in Pharmaceutical Grade AjiPure Glycine interact with 1 drug. Click any drug to see the details.

1 of the 1 ingredient in Pharmaceutical Grade AjiPure Glycine interact with drugs. Each result below shows which ingredient is responsible. Glycine

Each ingredient & the kinds of drugs it affects

For each ingredient in Pharmaceutical Grade AjiPure Glycine with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Glycine1 drug type · 1 drug

Clozapine (Clozaril)

Theoretically, glycine might decrease the effectiveness of clozapine.
One small clinical study in patients with schizophrenia shows that adding glycine to clozapine therapy worsens symptoms of schizophrenia when compared with clozapine alone. The mechanism of this interaction is unclear.

Likelihood Probable Evidence B
Glycine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pharmaceutical Grade AjiPure Glycine, from the product label.

Swanson Ultra

See all Swanson Ultra products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
www.swansonvitamins.com
Pharmacist Counseling Corner

Pharmaceutical Grade AjiPure Glycine by Swanson Ultra: Common Questions

Does Pharmaceutical Grade AjiPure Glycine by Swanson Ultra interact with any medications?
Yes. Based on its ingredients, Pharmaceutical Grade AjiPure Glycine has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pharmaceutical Grade AjiPure Glycine contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is glycine safe to take while pregnant or breastfeeding?
There isn't enough reliable safety data to know either way. The data we hold advises caution in both pregnancy and lactation. Talk with your doctor or pharmacist for personalized advice.
Will this help my schizophrenia?
Glycine is rated possibly effective for schizophrenia based on available evidence. However, one small study found that adding glycine to clozapine therapy actually worsened symptoms—so the picture is mixed. Your doctor can tell you whether it might work for your specific situation.
What side effects can glycine cause?
Mild sedation, irritability, insomnia, fatigue, memory impairment, and headache have been reported rarely. Soft stools, nausea, vomiting, upper GI discomfort, and dry mouth have also occurred rarely. Any symptoms that do occur typically resolve quickly once you stop taking it.
How long is it safe to take glycine?
Long-term safety data are limited, so we don't have solid information on that. Talk with your doctor or pharmacist about how long it's appropriate for you to use it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pharmaceutical Grade AjiPure Glycine is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pharmaceutical Grade AjiPure Glycine label
Go deeper

The Full Monographs Behind Pharmaceutical Grade AjiPure Glycine’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glycine

Interacts with 1 drug

Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep quality, where early research is promisin...

Read the full Glycine monograph →
Sources

Sources & How We Checked

Pharmaceutical Grade AjiPure Glycine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glycine 5 references
  1. Heresco-Levy U, Javitt DC, Ermilov M, et al. Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia. Arch Gen Psychiatry 1999;56:29-36.. PubMed
  2. Potkin SG, Jin Y, Bunney BG, Costa J, Gulasekaram B. Effect of clozapine and adjunctive high-dose glycine in treatment-resistant schizophrenia. Am J Psychiatry 1999;156:145-7.. PubMed
  3. Gusev EI, Skvortsova VI, Dambinova SA, et al. Neuroprotective effects of glycine for therapy of acute ischaemic stroke. Cerebrovasc Dis 2000;10:49-60. PubMed
  4. Inagawa K, Kawai N, Ono K, Sukegawa E, Tsubuku S, Takahashi M. Assessment of acute adverse effects of glycine ingestion at a high dose in human volunteers. Seikatsu Eisei. 2006; 50:27-32.
  5. Woods SW, Walsh BC, Hawkins KA, Miller TJ, Saksa JR, D'Souza DC, Pearlson GD, Javitt DC, McGlashan TH, Krystal JH. Glycine treatment of the risk syndrome for psychosis: report of two pilot studies. Eur Neuropsychopharmacol. 2013 Aug;23(8):931-40. PubMed

See these in context on the Glycine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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