No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Phosphatidyl Choline In Lecithin 420 mg Ingredients & Drug Interactions

by Source Naturals

Softgel Capsule Category: Fat/fatty Acid
No known interaction
The interaction bottom line No known interaction

Phosphatidyl Choline In Lecithin 420 mg is a dietary supplement by Source Naturals with 1 active ingredient. Its ingredients are commonly taken for liver health, memory and brain support, ulcerative colitis.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Phosphatidyl Choline In Lecithin 420 mg by Source Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This softgel contains one active ingredient: phosphatidylcholine, a compound that's a structural component of cell membranes and plays a role in cell communication and liver function. The inactive ingredients are gelatin (the capsule), glycerin, and purified water.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Phosphatidylcholine's overall clinical evidence instead.

Moderate

Some clinical evidence supports Phosphatidylcholine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Ulcerative colitis — rated "Possibly Effective" (Natural Medicines).

Phosphatidylcholine is possibly effective for ulcerative colitis (an inflammatory bowel condition). For nonalcoholic fatty liver disease, alcohol-related liver disease, Alzheimer disease, and anxiety, the evidence isn't established enough yet to rate it — more research is needed to know whether it helps with those conditions.

The evidence, ingredient by ingredient Phosphatidylcholine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Phosphatidylcholine is generally well tolerated at typical oral doses. The most common side effects are altered taste, bloating, diarrhea, itching, nausea, sweating, and vomiting.

Large doses (30 grams a day or more) are more likely to cause digestive upset and diarrhea. Choline is needed during pregnancy, but we don't have enough data on whether supplement doses beyond food sources are safe — talk with your doctor about whether to take this while pregnant.

For breastfeeding, there isn't enough reliable data either; check with your healthcare provider first.

Side effects, ingredient by ingredient Phosphatidylcholine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for phosphatidylcholine. Use the search tool on this page to check your specific medications before taking this product.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

This product may help if you have ulcerative colitis, though the evidence is moderate. It's generally well tolerated, though digestive side effects can happen.

Pregnancy and breastfeeding require a conversation with your doctor or pharmacist, since the safety data on supplement doses isn't complete. If you take any medications, use the search tool to double-check before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Phosphatidyl Choline In Lecithin 420 mg, straight from the product label.

Brand Source Naturals
Barcode (UPC) 021078006190
Net contents 90 Softgel(s)
Market status On market
Date entered into DSLD Aug 23, 2023
DSLD ID 296128
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Phosphatidyl Choline In Lecithin 420 mg by Source Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
90
UPC/BARCODE
021078006190
IngredientAmount% DV
Calories10 Calorie(s)--
Calories from Fat5 Calorie(s)--
Total Fat0.5 Gram(s)1%
Phosphatidyl Choline420 mg--

Other ingredients: Gelatin, Glycerin, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: 1 to 2 softgels daily.

Precautions

Note: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.

Do not use if either tamper-evident seal is broken or missing.

Keep out of the reach of children.

Formula

Source Naturals Phosphatidyl Choline provides premium quality and potency. This product has been concentrated to contain 3 times the phosphatidyl choline found in ordinary lecithin. This special soy lecithin also contains phosphatidyl inositol, phosphatidyl ethanolamine, and related phosphorus containing lipids. Phosphatidyl choline is a naturally occurring molecule that is composed of choline, phosphoric acid ad hydrocarbons. It is one of several phosphorus containing lipids that form the structural elements of all cell membranes in the body.

Formulation

Contains no yeast, dairy, egg, gluten, corn, soy or wheat. Contains no sugar, starch, salt, preservatives, or artificial color, flavor or fragrance.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Copyright Source Naturals, Inc.

See for yourself

Phosphatidyl Choline In Lecithin 420 mg by Source Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Phosphatidyl Choline In Lecithin 420 mg by Source Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container90 Amounts shown are per serving.

Phosphatidyl Choline

No known
interactions
420 mg per serving Form: Soy Lecithin

Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, bu...

Phosphatidyl Choline monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerin, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

Phosphatidyl Choline In Lecithin 420 mg by Source Naturals Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Phosphatidyl Choline In Lecithin 420 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Phosphatidyl Choline In Lecithin 420 mg, from the product label.

Source Naturals

Name
Source Naturals, Inc.
Street Address
P. O. Box 2118
City
Santa Cruz
State
CA
ZipCode
95062
Web Address
www.sourcenaturals.com
Pharmacist Counseling Corner

Phosphatidyl Choline In Lecithin 420 mg by Source Naturals: Common Questions

Does Phosphatidyl Choline In Lecithin 420 mg by Source Naturals interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Phosphatidyl Choline In Lecithin 420 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Phosphatidyl Choline In Lecithin 420 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does phosphatidylcholine do?
It's a natural compound found in cell membranes that supports cell communication and liver function. Research suggests it may help with ulcerative colitis, though more study is needed for other conditions like fatty liver disease and Alzheimer disease.
What are the most common side effects?
Altered taste, bloating, diarrhea, itching, nausea, sweating, and vomiting. These are generally mild, but higher doses are more likely to cause digestive upset. If side effects bother you, lower your dose or talk with your pharmacist.
Is it safe to take while pregnant?
Choline (which phosphatidylcholine contains) is needed in pregnancy, but we don't have solid safety data on supplement doses beyond what's in food. Check with your doctor about whether this product is right for you during pregnancy.
Is it safe while breastfeeding?
There isn't enough reliable data on supplement use while breastfeeding. Talk with your healthcare provider first to decide whether it's okay for you.
Does this really help with fatty liver disease or Alzheimer disease?
The evidence isn't established enough yet to say. Phosphatidylcholine is possibly effective for ulcerative colitis, but for fatty liver disease, Alzheimer disease, and other conditions, we need more research.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Phosphatidyl Choline In Lecithin 420 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Phosphatidyl Choline In Lecithin 420 mg label
Go deeper

The Full Monographs Behind Phosphatidyl Choline In Lecithin 420 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Phosphatidyl Choline In Lecithin 420 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phosphatidylcholine 15 references
  1. Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
  2. Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
  3. Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
  4. Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
  5. Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
  6. Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
  7. Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
  8. Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
  9. Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
  10. Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
  11. Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
  12. Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
  13. Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
  14. Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
  15. Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed

See these in context on the Phosphatidylcholine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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