Phosphatidylcholine 420 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Phosphatidylcholine 420 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Phosphatidylcholine 420 mg is a dietary supplement by Swanson Premium Brand with 1 active ingredient. Its ingredients are commonly taken for liver health, memory and brain support, ulcerative colitis.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Phosphatidylcholine 420 mg by Swanson Premium Brand
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This softgel contains one active ingredient: phosphatidylcholine at 420 mg per capsule. Phosphatidylcholine is a naturally occurring compound found in cell membranes and is involved in cell structure and function throughout your body.
The remaining ingredients are sunflower oil, gelatin, glycerin, and purified water — all inactive ingredients that give the softgel its form and stability.
Does it work?
Moderate evidence
The evidence for phosphatidylcholine is mixed. For ulcerative colitis (a type of inflammatory bowel disease), it's rated possibly effective based on available research.
For other uses listed here — nonalcoholic fatty liver disease, alcohol-related liver disease, Alzheimer disease, and anxiety — we don't have enough reliable evidence to say whether it works. If you're considering this supplement for any of these conditions, talk it over with your doctor to weigh what we know against your individual needs.
How safe is it?
Well-documented data
Phosphatidylcholine is generally well tolerated when taken by mouth, but high doses can cause digestive upset. Common side effects at lower doses include altered taste, bloating, diarrhea, nausea, vomiting, itching, and sweating.
Very high doses (30 grams daily) are more likely to trigger gastrointestinal problems. During pregnancy, choline (which phosphatidylcholine contains) is needed, but the safety of taking supplements beyond what's in food hasn't been well studied — check with your doctor before using this while pregnant.
There isn't enough data on this supplement during breastfeeding; talk with your healthcare provider first.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredient we checked. Even so, it's good practice to mention any new supplement to your pharmacist or doctor, especially if you have ongoing health concerns or take medications regularly.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.
This supplement may be worth considering if you're exploring options for ulcerative colitis, though the evidence is preliminary. If you're pregnant, breastfeeding, or have a history of digestive problems, run this by your doctor or pharmacist first.
Since no drug interactions are documented for this ingredient, you're not facing a medication conflict — but that doesn't replace a conversation with your own healthcare provider about whether it fits your health plan.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2018.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Phosphatidylcholine 420 mg, straight from the product label.
| Brand | Swanson Premium Brand |
|---|---|
| Barcode (UPC) | 087614018386 |
| Net contents | 200 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Apr 25, 2018 |
| DSLD ID | 175380 |
| Product type | Fat/fatty Acid |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Phosphatidylcholine 420 mg by Swanson Premium Brand, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 15 Calorie(s) | -- |
| Total Fat | 2 Gram(s) | 3% |
| Phosphatidylcholine | 840 mg | -- |
Other ingredients: Sunflower Oil, Gelatin, Glycerin, purified Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Bringing wellness to the world since 1969
To reorder, call toll free 1-800-437-4148 or visit our website at www.swansonvitamins.com
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Guaranteed purity & potency
Precautions
Do not use if seal is broken.
Keep out of reach of children.
Contains soy.
Storage
Store in a cool, dry place. Do not refrigerate.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take two softgels one to two times per day with water.
Formula
Contains soy.
General
SW838 Rev 1 05 09 17
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Phosphatidylcholine 420 mg by Swanson Premium Brand label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Phosphatidylcholine 420 mg by Swanson Premium Brand
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container100 Amounts shown are per serving.
Phosphatidylcholine
No knowninteractions
Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, bu...
Phosphatidylcholine monograph & interactionsOther (inactive) ingredients: Sunflower Oil, Gelatin, Glycerin, Purified Water. These complete the product’s ingredient list but are not active constituents.
Phosphatidylcholine 420 mg by Swanson Premium Brand Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Phosphatidylcholine 420 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Phosphatidylcholine 420 mg, from the product label.
Swanson Premium Brand
See all Swanson Premium Brand products- Name
- Swanson Health Products
- City
- Fargo
- State
- ND
- ZipCode
- 58104
- Phone Number
- 1-800-437-4148
- Web Address
- www.swansonvitamins.com
Phosphatidylcholine 420 mg by Swanson Premium Brand: Common Questions
Does Phosphatidylcholine 420 mg by Swanson Premium Brand interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is phosphatidylcholine, and what does it do in the body?
Does this supplement actually work for ulcerative colitis?
What side effects should I watch for?
Is it safe to take while pregnant?
Can I take this while breastfeeding?
Will this interact with my medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Phosphatidylcholine 420 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Phosphatidylcholine 420 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Phosphatidylcholine 420 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 15 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Phosphatidylcholine 15 references
- Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
- Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
- Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
- Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
- Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
- Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
- Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
- Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
- Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
- Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
- Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
- Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
- Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
- Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
- Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC