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Dietary supplement

Phyto-Gen Art-gen Ingredients & Drug Interactions

by Genestra Brands

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Phyto-Gen Art-gen is a dietary supplement by Genestra Brands with 3 active ingredients. Its ingredients are commonly taken for sore throat and mouth inflammation, skin wounds and irritation (topical), fever and general aches (traditional).Based on those ingredients, 2 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Black Alder Bud Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Phyto-Gen Art-gen by Genestra Brands

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Phyto-Gen Art-gen is a liquid formula with 3 active herbal extracts: black alder bud, olive shoot, and dogwood bud. The product also contains purified water, ethanol (alcohol), and glycerin as inactive ingredients.

We don't have established evidence that any of these ingredients work for a specific condition, so this product's intended purpose isn't clear from the safety data we hold.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The effectiveness ratings in our data show insufficient reliable evidence for olive leaf extract across several conditions—osteoporosis, GERD, exercise-related respiratory infections, shingles, flu, and osteoarthritis. We hold no effectiveness data for black alder bud extract or dogwood bud extract.

This means the evidence isn't established enough to say whether this formula actually works for what you're considering it for.

The evidence, ingredient by ingredient Black Alder Olive American Dogwood

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Black alder bud extract has limited safety data and may cause nausea or stomach upset, so use it cautiously and for short periods only. Olive shoot extract—when concentrated in supplement form—is less studied than whole olives or olive oil as food, though olive leaf extract itself appears well tolerated; headache and stomach discomfort were the most common side effects in trials, and one person reported acne.

Dogwood bud extract has very limited human safety data and cannot be considered well established as safe. Because black alder is not recommended during pregnancy or while breastfeeding, and dogwood bud extract also lacks reliable safety data for these times, the safety information advises against use in pregnancy and lactation.

For olive shoot extract, there's insufficient information to know either way—talk with your doctor or pharmacist for personalized advice if you're pregnant or nursing.

Side effects, ingredient by ingredient Black Alder Olive American Dogwood

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 3 matched ingredients can interact with medications — Black Alder.
  • The most serious interaction on file is rated Moderate.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start Phyto-Gen Art-gen, double-check with your doctor or pharmacist if you take cisplatin (Platinol-AQ) or doxorubicin (Adriamycin, others)—laboratory research suggests black alder bud extract may reduce how well these chemotherapy medications work. No other interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is geared toward people interested in herbal support, but the evidence for what it actually does isn't established in our data. If you take cisplatin or doxorubicin for cancer, skip this product or clear it with your own oncologist first—black alder may interfere with these drugs.

For anyone else on medications, check your exact drugs with the tool below. Pregnant women and those breastfeeding should talk with their doctor or pharmacist before using it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Phyto-Gen Art-gen, straight from the product label.

Brand Genestra Brands
Barcode (UPC) 883196116416
Net contents 0.5 Fluid Ounce(s); 15 mL
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 264415
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Phyto-Gen Art-gen by Genestra Brands, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.28 mL
Maximum serving Sizes:
0.28 mL
Servings per container
53
UPC/BARCODE
883196116416
IngredientAmount% DV
Black Alder Bud Extract0.09 mL--
Olive Shoot Extract0.09 mL--
Dogwood Bud Extract0.09 mL--

Other ingredients: purified Water, Ethanol, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended Dose: Take 10 drops once daily or as recommended by your health professional. Invert bottle to 45 degrees and shake lightly allowing drops to fall directly into mouth or in 1/4 oz of water.

Precautions

For warnings and additional information, see outer box.

Keep out of the reach of children.

Use only if safety seal is intact.

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

This product was sealed for your protection. Do not use if box or contents are open or damaged.

Storage

Store in a cool, dry place.

General Statements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

Scan to learn about our quality excellence V2 923-15U

FDA Statement of Identity

Dietary Supplement

Formula

Olive Dogwood Black Alder

See for yourself

Phyto-Gen Art-gen by Genestra Brands label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Phyto-Gen Art-gen by Genestra Brands

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.28 mL Dosage formLiquid Servings per container53 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Black Alder Bud Extract

Interacts with
2 drugs
0.09 mL per serving

Black Alder is a European tree whose bark and leaves have a long history in folk medicine, mainly as an astringent gargle or wound wash. There is very...

Black Alder Bud Extract monograph & interactions

Olive Shoot Extract

No known
interactions
0.09 mL per serving

Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyr...

Olive Shoot Extract monograph & interactions

Dogwood Bud Extract

No known
interactions
0.09 mL per serving Form: Cornus sanguinea Bud Extract

American Dogwood is a North American flowering tree whose bark was used in traditional folk medicine, especially as a substitute for quinine to treat...

Dogwood Bud Extract monograph & interactions

Other (inactive) ingredients: Purified Water, Ethanol, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Phyto-Gen Art-gen by Genestra Brands Drug Interactions

Want to check YOUR meds against Phyto-Gen Art-gen?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2Drugs
2 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Phyto-Gen Art-gen with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Black Alder Bud Extract2 drug types · 2 drugs

Cisplatin (Platinol-Aq)

Laboratory research shows that black alder bark extracts can antagonize the chemotherapeutic effects of cisplatin. This interaction has not been evaluated in humans. Until more is known, use this combination with caution.

Likelihood Possible Evidence D
Doxorubicin (Adriamycin, Others)

Laboratory research shows that black alder bark extracts can antagonize the chemotherapeutic effects of doxorubicin. This interaction has not been evaluated in humans. Until more is known, use this combination with caution.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Phyto-Gen Art-gen, from the product label.

Genestra Brands

Name
Seroyal USA
City
Pittsburgh
State
PA
ZipCode
15275
Phone Number
1-888-737-6925
Web Address
seroyal.com
Pharmacist Counseling Corner

Phyto-Gen Art-gen by Genestra Brands: Common Questions

Does Phyto-Gen Art-gen by Genestra Brands interact with any medications?
Yes. Based on its ingredients, Phyto-Gen Art-gen has a known interaction with 2 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Phyto-Gen Art-gen contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant?
Black alder bud extract and dogwood bud extract should be avoided during pregnancy according to the safety information we have. For olive shoot extract, there isn't enough data to know either way. Talk with your doctor or pharmacist before using this product if you're pregnant—they can give you personalized advice.
Can I take this while breastfeeding?
Black alder bud extract and dogwood bud extract are not recommended while breastfeeding because safety data are insufficient or absent. For olive shoot extract, there's not enough information to know if it's safe. Check with your doctor or pharmacist before using this product if you're nursing.
What are the side effects?
Black alder bud extract may cause nausea or stomach upset. Olive shoot extract is generally well tolerated, though headache and stomach discomfort were reported in clinical trials, and one person developed acne. Dogwood bud extract has very limited safety data, so side effects aren't well known.
Does this product actually work?
We don't have established evidence that any of the three ingredients in this formula work for a specific condition. Olive leaf extract has been studied for osteoporosis, GERD, infections, shingles, flu, and osteoarthritis, but the evidence is insufficient to say it works. For the other two ingredients, we hold no effectiveness data.
Why does this product contain alcohol (ethanol)?
Ethanol is listed as an inactive ingredient—it's used in the liquid formulation to preserve and extract the herbal ingredients. The amount present is what's typical for herbal liquid supplements.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Phyto-Gen Art-gen is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Phyto-Gen Art-gen label
Sources

Sources & How We Checked

Phyto-Gen Art-gen's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Alder 1 reference
  1. Dinic J, Novakovic M, Podolski-Renic A, et al. Antioxidative activity of diarylheptanoids from the bark of black alder (Alnus glutinosa) and their interaction with anticancer drugs. Planta Med 2014;80(13):1088-96. doi: 10.1055/s-0034-1382993. Epub 2014 Au PubMed

See these in context on the Black Alder monograph →

Olive 2 references
  1. Liccardi G, D'Amato M, D'Amato G. Oleaceae pollinosis: a review. Int Arch Allergy Immunol 1996;111:210-7. PubMed
  2. Somerville V, Moore R, Braakhuis A. The effect of olive leaf extract on upper respiratory illness in high school athletes: A randomised control trial. Nutrients. 2019;11(2). pii: E358. PubMed

See these in context on the Olive monograph →

American Dogwood 1 reference
  1. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source

See these in context on the American Dogwood monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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