Phyto-Gen Gluco-gen Ingredients & Drug Interactions
by Genestra Brands
What is this page for?
First and foremost: checking Phyto-Gen Gluco-gen against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Phyto-Gen Gluco-gen is a dietary supplement by Genestra Brands with 3 active ingredients. Its ingredients are commonly taken for heart health, high blood pressure, high cholesterol.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Phyto-Gen Gluco-gen by Genestra Brands
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Phyto-Gen Gluco-gen contains three active plant extracts. Olive young shoot extract, black poplar bud extract, and English walnut bud extract make up the formula in a base of purified water, ethanol, and glycerin.
The product is a liquid, so you're getting these extracts in a concentrated form rather than whole plant material. The inactive ingredients are water, alcohol, and glycerin — common carriers for liquid herbal supplements.
Does it work?
Moderate evidence
The evidence we hold doesn't establish that this product works for any specific condition. Olive young shoot extract shows insufficient reliable evidence for osteoporosis, GERD, exercise-related respiratory infections, shingles, flu, and osteoarthritis.
English walnut bud extract is rated possibly effective for high cholesterol (hypercholesterolemia), but insufficient evidence for heart disease and diabetes. We hold no effectiveness data for black poplar bud extract.
How safe is it?
Well-documented data
Olive young shoot extract is generally well tolerated in typical doses. The most common side effects reported are headache and stomach discomfort; one person in a trial reported acne.
Concentrated olive supplements are less studied than olive oil and olives as food, so caution is advised unless your doctor approves. English walnut bud extract carries an important caution: walnuts can trigger serious allergic reactions in people with tree nut allergies, including oral allergy syndrome (itching in the mouth) or rarely swelling of the lips and tongue.
Walnut leaf extract has been reported to cause mild diarrhea in about 39% of adults in one study, and may cause soft stools and mild bloating. The safety of concentrated walnut leaf and husk extracts is not well studied.
English walnut is rated possibly unsafe in pregnancy and likely safe in breastfeeding, though data is limited.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. However, we do not hold interaction data for black poplar bud extract, so we cannot rule out interactions with it.
Check your exact medications with the search tool on this page before you start.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.
If you have high cholesterol and are interested in possibly effective remedies, you might consider talking with your doctor about whether walnut supplements fit into your plan — though the evidence here is modest. If you have a tree nut allergy, skip this product.
Before you start, check your medications with the tool on this page, and talk with your own doctor or pharmacist about whether it's appropriate for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Phyto-Gen Gluco-gen, straight from the product label.
| Brand | Genestra Brands |
|---|---|
| Barcode (UPC) | 883196127405 |
| Net contents | 0.5 fl. Oz.; 15 mL |
| Market status | On market |
| Date entered into DSLD | Jul 23, 2020 |
| DSLD ID | 231418 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Phyto-Gen Gluco-gen by Genestra Brands, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Olive (Olea europaea) young shoot extract | 0.09 mL | -- |
| Black Poplar (Populus nigra) bud extract | 0.09 mL | -- |
| English Walnut (Juglans regia) bud extract | 0.09 mL | -- |
Other ingredients: purified Water, Ethanol, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Recommended Dose: Take 10 drops once daily or as recommended by your health professional. Invert bottle to 45 degrees and shake lightly allowing drops to fall directly into mouth or in 1/4 oz of water.
General Statements
For warnings and additional information, see outer box.
Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.
Scan to learn about our quality excellence
Precautions
Keep out of the reach of children.
Use only if safety seal is intact.
Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.
This product was sealed for your protection. Do not use if box or contents are open or damaged.
Storage
Store in a cool, dry place.
Formula
English Walnut Olive Black Poplar
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Phyto-Gen Gluco-gen by Genestra Brands label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Phyto-Gen Gluco-gen by Genestra Brands
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.28 mL Dosage formLiquid Servings per container53 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Olive (Olea europaea) young shoot extract
No knowninteractions
Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyr...
Olive (Olea europaea) young shoot extract monograph & interactionsBlack Poplar (Populus nigra) bud extract
English Walnut (Juglans regia) bud extract
No knowninteractions
English walnut is a nutritious tree nut rich in plant-based omega-3 fats, fiber, and antioxidants, and eating it as part of a balanced diet may suppor...
English Walnut (Juglans regia) bud extract monograph & interactionsOther (inactive) ingredients: Purified Water, Ethanol, Glycerin. These complete the product’s ingredient list but are not active constituents.
Phyto-Gen Gluco-gen by Genestra Brands Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Phyto-Gen Gluco-gen. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Phyto-Gen Gluco-gen, from the product label.
Genestra Brands
- Name
- Seroyal USA
- City
- Pittsburgh
- State
- PA
- ZipCode
- 15275
- Phone Number
- 1-888-737-6925
- Web Address
- seroyal.com
Phyto-Gen Gluco-gen by Genestra Brands: Common Questions
Does Phyto-Gen Gluco-gen by Genestra Brands interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I have a tree nut allergy?
Will this help my cholesterol?
What are the most common side effects?
Is this safe to take during pregnancy?
Is this safe while breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Phyto-Gen Gluco-gen is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Phyto-Gen Gluco-gen’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Olive
Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyrosol. Olive oil as part of a Mediterrane...
Read the full Olive monograph → Herb & supplement monographEnglish Walnut
English walnut is a nutritious tree nut rich in plant-based omega-3 fats, fiber, and antioxidants, and eating it as part of a balanced diet may support heart health. Most concentrated supple...
Read the full English Walnut monograph →Sources & How We Checked
Phyto-Gen Gluco-gen's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 18 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Olive 2 references
- Liccardi G, D'Amato M, D'Amato G. Oleaceae pollinosis: a review. Int Arch Allergy Immunol 1996;111:210-7. PubMed
- Somerville V, Moore R, Braakhuis A. The effect of olive leaf extract on upper respiratory illness in high school athletes: A randomised control trial. Nutrients. 2019;11(2). pii: E358. PubMed
English Walnut 16 references
- Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Zambon D, Sabate J, Munoz S, et al. Substituting walnuts for monounsaturated fat improves the serum lipid profile of hypercholesterolemic men and women. A randomized crossover trial. Ann Intern Med 2000;132:538-46. PubMed
- Chisholm A, Mann J, Skeaff M, et al. A diet rich in walnuts favourably influences plasma fatty acid profile in moderately hyperlipidaemic subjects. Eur J Clin Nutr 1998;52:12-6. PubMed
- Sabate J, Fraser GE, Burke K, et al. Effects of walnuts on serum lipid levels and blood pressure in normal men. N Engl J Med 1993;328:603-7. PubMed
- Feldman EB. The scientific evidence for a beneficial health relationship between walnuts and coronary heart disease. J Nutr 2002;132:1062S-101S. PubMed
- Asero R. Detection and clinical characterization of patients with oral allergy syndrome caused by stable allergens in Rosaceae and nuts. Ann Allergy Asthma Immunol 1999;83:377-83. PubMed
- Bonamonte D, Foti C, Angelini G. Hyperpigmentation and contact dermatitis due to Juglans regia. Contact Dermatitis 2001;44:101-2. PubMed
- Hu FB, Stampfer MJ. Nut consumption and risk of coronary heart disease: a review of epidemiologic evidence. Curr Atheroscler Rep 1999;1:204-9. PubMed
- Tapsell LC, Gillen LJ, Patch CS, et al. Including walnuts in a low-fat/modified-fat diet improves HDL cholesterol-to-total cholesterol ratios in patients with type 2 diabetes. Diabetes Care 2004;27:2777-83. PubMed
- Rabiei K, Ebrahimzadeh MA, Saeedi M, et al. Effects of a hydroalcoholic extract of Juglans regia (walnut) leaves on blood glucose and major cardiovascular risk factors in type 2 diabetic patients: a double-blind, placebo-controlled clinical trial. BMC Com PubMed
- Hosseini S, Jamshidi L, Mehrzadi S, et al. Effects of Juglans regia L. leaf extract on hyperglycemia and lipid profiles in type two diabetic patients: a randomized double-blind, placebo-controlled clinical trial. J Ethnopharmacol. 2014;152(3):451-6. PubMed
- FDA. Qualified Health Claims: Letter of Enforcement Discretion - Walnuts and Coronary Heart Disease (Docket No 02P-0292). March 2004. Available at: http://wayback.archive-it.org/7993/20171114183649/https:/www.fda.gov/Food/IngredientsPackagingLabeling/Labe
- Food and Drug Administration. Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA); Public Law 108-282, Title II. Accessed on May 19, 2021. Available at: https://www.fda.gov/food/food-allergensgluten-free-guidance-documents-regulatory-infor
- Mirzababaei A, Daneshvar M, Abaj F, et al. The Effect of Walnut (Juglans regia) Leaf Extract on Glycemic Control and Lipid Profile in Patients With Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Clin Nutr Re
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC