Interaction check not available yet — this product's ingredients haven't been matched to our database.
Dietary supplement

Phytosterol Complex with Beta Sitosterol Ingredients & Drug Interactions

by Puritan's Pride

Softgel Capsule Category: Fat/fatty Acid
No known interaction
The interaction bottom line No known interaction

Phytosterol Complex with Beta Sitosterol is a dietary supplement by Puritan's Pride with 1 active ingredient.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Phytosterol Complex with Beta Sitosterol by Puritan's Pride

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Sterol Esters” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Phytosterol Complex” is a proprietary blend — the label gives one combined amount (1,000 mg) without saying how much of each component you get.

This product contains three active ingredients: Beta-Sitosterol, Stigmasterol, and Campsterols — all plant-derived compounds called phytosterols. Beta-sitosterol is the most researched of the three and is known to support cholesterol levels and prostate health.

The product also contains inactive ingredients like gelatin, glycerin, soybean oil, citrus pectin, and turmeric as fillers and capsule material.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support heart health and cholesterol levels.
  • We looked for evidence on: Coronary heart disease (CHD), Familial hypercholesterolemia, Dyslipidemia, Atherosclerosis.
  • The strongest evidence on file: Beta-sitosterol is rated "Possibly Effective" for Coronary heart disease (CHD) (Natural Medicines).
  • Also on file: Beta-sitosterol is rated "Possibly Effective" for Familial hypercholesterolemia.

Beta-sitosterol is likely effective for benign prostatic hyperplasia (enlarged prostate) — the research here is solid. It's possibly effective for familial high cholesterol and coronary heart disease, meaning the evidence suggests it may help, but more research would strengthen that claim.

We don't have effectiveness data on file for Stigmasterol or Campsterols individually.

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-sitosterol is generally well tolerated when taken short-term, though the most common side effects are digestive: constipation, diarrhea, gas, indigestion, and nausea. It may also reduce appetite or worsen acne in some people.

There's one case report of pancreatitis tied to beta-sitosterol use, though symptoms didn't return when the person stopped. Because there isn't enough safety data, avoid this supplement during pregnancy and while breastfeeding — talk with your doctor or pharmacist if you're in either situation.

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for the ingredients we could check in this product. Still, double-check your exact medications with the tool on this page before you start — we don't hold data for Stigmasterol and Campsterols.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This one's a solid choice if you're looking to support prostate health or manage cholesterol — beta-sitosterol has real evidence behind it. If you have digestive sensitivity or are pregnant or nursing, check with your pharmacist first.

Run your medications through our tool before you start, even though no interactions showed up in our data.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Phytosterol Complex with Beta Sitosterol, straight from the product label.

Brand Puritan's Pride
Barcode (UPC) 025077139811
Net contents 100 Rapid Release Softgel(s)
Market status On market
Date entered into DSLD Aug 22, 2024
DSLD ID 318170
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Approved Health, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Phytosterol Complex with Beta Sitosterol by Puritan's Pride, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
50
UPC/BARCODE
025077139811
IngredientAmount% DV
Sterol Esters0 NP--
Beta-Sitosterol0 NP--
Stigmasterol0 NP--
Phytosterol Complex1000 mg--
Campsterols0 NP--

Other ingredients: Gelatin, Glycerin, Soybean Oil, Citrus Pectin, Turmeric

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Puritan's Pride supplements are produced from the finest raw materials under stringent quality control standards. State-of-the-art manufacturing and packaging facilities ensure you the highest quality nutritional supplements money can buy. When it comes to your health... choose the best.

To reorder item # 13981 www.puritan.com 1-800-645-1030

Precautions

Warning: if you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur. Do not use if seal under cap is broken or missing.

Keep out of reach of children.

Formulation

No artificial flavor or sweetener, no sugar, no starch, no milk, no lactose, no soy, no gluten, no wheat, no yeast, no fish. Sodium free.

Different color same product May reduce the risk of heart disease

Contains ingredients that may result in a variation of color and appearance over time.

Formula

Diets low in saturated fat and cholesterol that include 2 g per day of phytosterols eaten with meals or snacks may reduce the risk of heart disease. A serving of Phytosterol Complex supplies 0.5 g of phytosterols.

Scientific evidence demonstrates that diets that include phytosterols may reduce the risk of coronary heart disease. Our specialized formula exceeds strict quality standards for levels of phytosterols (beta sitosterol, stigmasterol, and campesterol)- the active ingredients that help maintain cholesterol levels already within a normal range.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease.

Storage

Store at room temperature.

Seals/Symbols

Quality Assured

Brand IP Statement(s)

Copyright 2022 Puritan's Pride, Inc.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: for adults, take two (2) softgels twice daily, with your two largest meals of the day.

See for yourself

Phytosterol Complex with Beta Sitosterol by Puritan's Pride label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Phytosterol Complex with Beta Sitosterol by Puritan's Pride

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container50 Amounts shown are per serving.

Phytosterol Complex

1000 mg per serving
  • › Sterol Esters

Other (inactive) ingredients: Gelatin, Glycerin, Soybean Oil, Citrus Pectin, Turmeric. These complete the product’s ingredient list but are not active constituents.

Interaction report

Phytosterol Complex with Beta Sitosterol by Puritan's Pride Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Phytosterol Complex with Beta Sitosterol. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Phytosterol Complex with Beta Sitosterol, from the product label.

Puritan's Pride

See all Puritan's Pride products
Name
Puritan's Pride, Inc.
City
Ronkonkoma
State
NY
ZipCode
11779
Phone Number
1-800-645-1030
Web Address
www.puritan.com
Pharmacist Counseling Corner

Phytosterol Complex with Beta Sitosterol by Puritan's Pride: Common Questions

Does Phytosterol Complex with Beta Sitosterol by Puritan's Pride interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Phytosterol Complex with Beta Sitosterol. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Phytosterol Complex with Beta Sitosterol contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is beta-sitosterol and why is it in here?
Beta-sitosterol is a plant compound that helps support prostate health and cholesterol levels. It's the main active ingredient in this product and the one with the strongest research backing it.
Will this help my prostate?
Beta-sitosterol is likely effective for benign prostatic hyperplasia — enlarged prostate — so yes, there's solid evidence it can help. For other prostate issues, talk with your doctor about whether this is right for you.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety data to recommend supplemental beta-sitosterol during pregnancy or while breastfeeding. Talk with your doctor or pharmacist for personalized advice if you're in either situation.
What side effects should I expect?
Most people tolerate it well, but digestive side effects are most common — constipation, diarrhea, gas, indigestion, and nausea. Some people also report reduced appetite. Stop and check with your pharmacist if you have problems.
Does this really have no interactions with my medications?
No interactions are documented for beta-sitosterol, which is the main ingredient. But we don't have data on Stigmasterol and Campsterols, so use the checker below with your exact medications to be sure.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Phytosterol Complex with Beta Sitosterol is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Phytosterol Complex with Beta Sitosterol label
Sources

Sources & How We Checked

Phytosterol Complex with Beta Sitosterol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-sitosterol 7 references
  1. Berges RR, Windeler J, Trampisch HJ, et al. Randomised, placebo-controlled, double-blind clinical trial of beta-sitosterol in patients with benign prostatic hyperplasia. Beta-sitosterol Study Group. Lancet 1995;345:1529-32.
  2. Klippel KF, Hiltl DM, Schipp B. A multicentric, placebo-controlled, double-blind clinical trial of beta-sitosterol (phytosterol) for the treatment of benign prostatic hyperplasia. Br J Urol 1997;80:427-32.
  3. Wilt TJ, MacDonald R, Ishani A. beta-sitosterol for the treatment of benign prostatic hyperplasia: a systematic review. BJU Int 1999;83:976-83. PubMed
  4. Oster P, Schlierf G, Heuck CC, et al. [Sitosterol in familial hyperlipoproteinemia type II. A randomized, double-blind, cross-over study]. Dtsch Med Wochenschr 1976;101:1308-11.
  5. Becker M, Staab D, Von Bergman K. Long-term treatment of severe familial hypercholesterolemia in children: effect of sitosterol and bezafibrate. Pediatrics 1992;89:138-42. DOI
  6. Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
  7. Lorenze A, Hsueh W, Nasr J. Beta-sitosterol-induced acute pancreatitis: A case report and review of the literature. Cureus. 2020;12(3):e7407. PubMed

See these in context on the Beta-sitosterol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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