No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Pipsissewa Ingredients & Drug Interactions

by Hawaii Pharm

Liquid Category: Botanical
No known interaction
The interaction bottom line No known interaction

Pipsissewa is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for urinary tract support, diuretic (increasing urine flow), mild inflammation.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Pipsissewa by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Pipsissewa Leaf Extract, Dry. Pipsissewa is a plant used traditionally in herbal medicine, though modern research into what it does and how safe it is remains limited.

The liquid also contains alcohol, water, and glycerin as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Pipsissewa product and its label doesn't state a use — see Pipsissewa's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't have effectiveness data on file for Pipsissewa. Because this supplement has been used traditionally for a long time, people have experience with it, but we lack the modern research to say what it actually does or how well it works.

The evidence, ingredient by ingredient Pipsissewa

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Here's what matters: chronic use of Pipsissewa may lead to hydroquinone toxicity — a buildup of a compound that can cause serious symptoms like ringing in the ears (tinnitus), vomiting, confusion (delirium), seizures (convulsions), and collapse. The safety data advises against use during pregnancy and breastfeeding.

Overall, modern safety information on this product is limited, so talk with your pharmacist or doctor before starting it, especially if you plan long-term use.

Side effects, ingredient by ingredient Pipsissewa

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for Pipsissewa in our data. However, because this product contains alcohol, mention it to your pharmacist if you take medications that don't mix well with alcohol.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Pipsissewa is a traditional plant extract with very little modern research behind it. If you're curious about it, check with your pharmacist first — they can discuss the limited safety data and whether it's right for you, particularly if you're pregnant, breastfeeding, or taking other medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pipsissewa, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 840253641472
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Oct 24, 2023
DSLD ID 301753
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pipsissewa by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
840253641472
IngredientAmount% DV
Pipsissewa Leaf Extract, Dry983 mg--

Other ingredients: Alcohol, Water, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Hawaii Pharm Herbal Extract Highest quality since 2008

Suggested/Recommended/Usage/Directions

Suggested use: Shake well before using. For adults add about 20-30 drops (0.7-1 mL, one full squeeze of the dropper bulb) to some juice or water, up to 4 times a day.

Precautions

Warning: We recommend to seek expert medical advice before taking.

Do not use if you are allergic to any ingredients.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

May affect the ability to drive and operate machinery. May have contraindications, can cause side effects and adverse reactions. Do not use if seal is broken or missing.

Keep out of the reach of children!

Storage

Store in a cool dry place.

Seals/Symbols

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

Organic Alcohol Based USA Made in United States of America

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Scan this QR-code to get 15% discount on your next purchase. Limited time deal.

Formula

Chimaphila umbellata

Organic Alcohol Based

Formulation

Only natural ingredients Purity is laboratory tested and verified

All the raw materials are gluten-free by their nature No artificial colors, flavors, or preservatives

Not tested on animals

Organic Alcohol Based

Made in USA, Hawaii

FDA Statement of Identity

Herbal Supplement

See for yourself

Pipsissewa by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pipsissewa by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Pipsissewa Leaf Extract, Dry

No known
interactions
983 mg per serving

Pipsissewa is a North American forest herb with a long history of traditional use as a diuretic and urinary remedy, but modern human research is very...

Pipsissewa Leaf Extract, Dry monograph & interactions

Other (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pipsissewa by Hawaii Pharm Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Pipsissewa. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Pipsissewa, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
Street Address
510 Sumner St. Ste. 613
City
Honolulu
State
HI
ZipCode
96817
Phone Number
888-854-2924
Web Address
www.hawaiipharm.com
Pharmacist Counseling Corner

Pipsissewa by Hawaii Pharm: Common Questions

Does Pipsissewa by Hawaii Pharm interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Pipsissewa. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Pipsissewa contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant?
The safety data advises against Pipsissewa during pregnancy because there isn't enough information to know it's safe. Talk with your doctor or pharmacist about whether this is right for you.
Is it safe to use while breastfeeding?
No reliable safety information exists for breastfeeding, so the data advises against it. Your pharmacist or doctor can discuss safer options with you.
What does Pipsissewa actually do?
Pipsissewa has a long history of traditional use, but we don't have modern research on file that explains what it does or how well it works. That's something to ask your pharmacist about.
What are the side effects?
With chronic (long-term) use, Pipsissewa may cause hydroquinone toxicity — a buildup that can lead to ringing in the ears, vomiting, confusion, seizures, and collapse. If you notice any of these, stop and contact your doctor right away.
Does this product contain alcohol?
Yes, it's a liquid extract made with alcohol, water, and glycerin. If you avoid alcohol for any reason, let your pharmacist know.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pipsissewa is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pipsissewa label
Go deeper

The Full Monographs Behind Pipsissewa’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Pipsissewa's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pipsissewa 1 reference
  1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.

See these in context on the Pipsissewa monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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