Protein Optimize Ingredients & Drug Interactions
by Enzymedica
What is this page for?
First and foremost: checking Protein Optimize against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Protein Optimize is a dietary supplement by Enzymedica with 6 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Protein Optimize by Enzymedica
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Protein Optimize contains 6 active ingredients, all variations of protease — enzymes that break down proteins in your digestive tract. You get Protease, Protease 4.5, Protease 3, Protease 6, and Protease Thera-blend #884, plus Peptidase.
The capsule itself is vegetarian.
Does it work?
Couldn't assess
We hold no effectiveness data for the ingredients in this product, so we can't tell you from our records whether it lives up to its claims. If you're looking at this for a specific reason — digestive support, recovery, or something else — that's worth discussing with your doctor or pharmacist.
How safe is it?
Well-documented data
These proteases are generally well tolerated by most adults, though some people do report digestive upset or allergic reactions. Rarely, occupational exposure to airborne proteases has triggered allergic rhinitis or asthma in case reports, and protease-specific allergic responses have been documented in people exposed through laundry products.
If you're pregnant, safety hasn't been established, so it's best avoided unless your doctor prescribes it. During breastfeeding, there's little safety data, so medical advice is needed before use.
Meds to double-check
No known interactions
No medication interactions are documented in our data for the protease ingredients in this product. We could not check Peptidase.
If you're on any medications, use the interaction checker on this page or ask your pharmacist before taking it.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.
If you're an adult looking to add digestive enzymes and you don't have a documented protease allergy, this product is generally well tolerated. Anyone pregnant or breastfeeding should check with their doctor or pharmacist first.
No medication interactions are documented for the ingredients we could verify, but run your own medications through the checker and talk it over with your healthcare provider before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2014.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Protein Optimize, straight from the product label.
| Brand | Enzymedica |
|---|---|
| Barcode (UPC) | 670480280102 |
| Net contents | 90 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Apr 25, 2014 |
| DSLD ID | 32682 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Protein Optimize by Enzymedica, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Protease | 0 NP | -- |
| Peptidase | 0 NP | -- |
| Protease 4.5 | 0 NP | -- |
| Protease 3 | 0 NP | -- |
| Protease 6 | 0 NP | -- |
| Protease Thera-blend(TM) #884 | 52000 HUT | -- |
| Thera-blend(TM) #884 | 0 NP | -- |
Other ingredients: 100% Vegetarian Capsule
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Our exclusive Thera-blend(TM) enzymes are effective throughout the entire digestive system, thereby ensuring complete digestion.
General Statements
When formulated for therapeutic purposes, Thera-blend enzymes are customized for optimal performance throughout the entire body.
SUPPORTIVE
Protein Optimize is ideal for individuals on a high protein regimen.* This formula is meant to reduce the digestive load and increase maximum nutrient availability. It is composed of a unique selection of protein digesting enzymes to increase availability of essential peptides and amino acids.*
MADE IN USA
PLANT-BASED ENZYMES
The Enzyme Experts
MAXIMIZE HIGH PROTEIN MEALS - Ideal for soy, whey, casein and rice proteins - Improve protein digestion - Maximize sport nutrition
Seals/Symbols
#1 SELLING ENZYME BRAND
vitaminangels
AUTISM HOPE ALLIANCE AHA
VERIFIED BeGreen
K PARVE #K1840
Formulation
ABSOLUTELY NO FILLERS ADDED
VEGAN & KOSHER
CONTAINS NO egg, dairy, salt, sucrose, soy, wheat, yeast, corn, gluten, casein, potato, rice, artificial colors or flavors.
Suggested/Recommended/Usage/Directions
Recommended Usage: One capsule per 20 grams of protein. More may be taken as needed or when recommended by your healthcare provider.*
FDA Disclaimer Statement
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formula
VEGAN & KOSHER
FDA Statement of Identity
DIETARY SUPPLEMENT
Storage
Keep closed in dry place; do not expose to excessive heat.
Precautions
AS WITH ALL PRODUCTS, PLEASE KEEP OUT OF REACH OF CHILDREN
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Protein Optimize by Enzymedica label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Protein Optimize by Enzymedica
These are the 6 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Protease Thera-blend(TM) #884
No knowninteractions
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...
Protease Thera-blend(TM) #884 monograph & interactionsThera-blend(TM) #884
- › Protease
- › Peptidase
- › Protease 4.5
- › Protease 3
- › Protease 6
Other (inactive) ingredients: 100% Vegetarian Capsule. These complete the product’s ingredient list but are not active constituents.
Protein Optimize by Enzymedica Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Protein Optimize. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Protein Optimize, from the product label.
Enzymedica
See all Enzymedica products- Name
- Enzymedica, Inc.
- Street Address
- 752 Tamiami Trail
- City
- Port Charlotte
- State
- FL
- ZipCode
- 33953
- Phone Number
- 1-888-918-1118
- Web Address
- www.enzymedica.com
Protein Optimize by Enzymedica: Common Questions
Does Protein Optimize by Enzymedica interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What are these protease enzymes supposed to do?
Can I take this while I'm pregnant?
Is it safe while breastfeeding?
Could this cause side effects?
Does this interact with my medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Protein Optimize is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Protein Optimize’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Protein Optimize's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC