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Dietary supplement

Pumpkin Seed 450 mg Ingredients & Drug Interactions

by TerraVita Premium Collection

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Pumpkin Seed 450 mg is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, overactive bladder, eye and skin health (vitamin a source).Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pumpkin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Pumpkin Seed 450 mg by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This supplement contains one active ingredient: pumpkin seed at 450 mg per capsule. The capsule shell is made from gelatin and water.

The product is straightforward — just the pumpkin seed and the capsule itself, with no added fillers.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: prostate and urinary tract health.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Overactive bladder, urinary symptoms, lower urinary tract symptoms.
  • The strongest evidence on file: Pumpkin is rated "Possibly Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Pumpkin is rated "Insufficient Reliable Evidence To Rate" for Overactive bladder.

The evidence behind pumpkin seed is mixed. It's rated possibly effective for benign prostatic hyperplasia (BPH), a condition where the prostate gland enlarges and can affect urination in older men.

For other uses — including male-pattern hair loss, interstitial cystitis (bladder pain), parasite infection, and urinary tract infections — the evidence isn't established in the data we hold.

The evidence, ingredient by ingredient Pumpkin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pumpkin as a food is generally well tolerated. When you take it as a concentrated supplement like this, most people don't have problems.

Common side effects that have been reported in trials include abdominal discomfort, diarrhea, nausea, and vomiting — though these are not frequent. Rarely, anaphylaxis (a severe allergic reaction) has been reported.

There are also two case reports of temporary hair loss after eating bitter-tasting pumpkin or squash, attributed to high levels of a compound called cucurbitacin found in wild varieties. Because safety data on concentrated seed supplements during pregnancy and breastfeeding is limited, talk with your doctor or pharmacist about whether it's right for you before using it.

Side effects, ingredient by ingredient Pumpkin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Pumpkin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take lithium, double-check with your doctor or pharmacist before starting this supplement — pumpkin may reduce lithium excretion and raise its levels in your body, potentially requiring a dose adjustment. For all other medications, no interactions are documented in our data; however, this doesn't guarantee none exist, so it's still wise to run through your exact medications with your healthcare provider.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Pumpkin seed may help with an enlarged prostate, though more evidence would strengthen that case. If you take lithium, you'll need to check with your doctor or pharmacist before starting — the supplement could affect how your body processes that medication.

For other uses, the evidence isn't clear. It's generally well tolerated, but discuss it with your own healthcare provider to make sure it fits your health picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pumpkin Seed 450 mg, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064435108311
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Jan 23, 2023
DSLD ID 285898
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pumpkin Seed 450 mg by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
064435108311
IngredientAmount% DV
Pumpkin450 mg--

Other ingredients: Gelatin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2004 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions Take 1 capsule 3 times daily, with meals.

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Pumpkin Seed 450 mg by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pumpkin Seed 450 mg by TerraVita Premium Collection

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Pumpkin

Interacts with
1 drug
450 mg per serving

Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The...

Pumpkin monograph & interactions

Other (inactive) ingredients: Gelatin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pumpkin Seed 450 mg by TerraVita Premium Collection Drug Interactions

Want to check YOUR meds against Pumpkin Seed 450 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Pumpkin Seed 450 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Pumpkin1 drug type · 1 drug

Lithium

Pumpkin might reduce excretion and increase levels of lithium.
Pumpkin is thought to have diuretic properties. Theoretically, this might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Pumpkin Seed 450 mg, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Pumpkin Seed 450 mg by TerraVita Premium Collection: Common Questions

Does Pumpkin Seed 450 mg by TerraVita Premium Collection interact with any medications?
Yes. Based on its ingredients, Pumpkin Seed 450 mg has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pumpkin Seed 450 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does pumpkin seed actually help with prostate problems?
The evidence suggests it may help with benign prostatic hyperplasia (BPH), where the prostate gland enlarges. We'd rate that as possibly effective — meaning there's some support, but we'd like to see more solid research before calling it a sure thing.
What side effects might I notice?
Most people tolerate pumpkin seed well. If you do have side effects, they're typically mild — abdominal discomfort, diarrhea, nausea, or vomiting. Severe allergic reactions are very rare. Avoid bitter-tasting pumpkin or squash, since case reports link high levels of a compound in those to temporary hair loss.
Can I take this while pregnant or breastfeeding?
There isn't enough data on concentrated pumpkin seed supplements during pregnancy or breastfeeding to know if it's safe. Talk with your doctor or pharmacist — they can give you personalized advice based on your situation.
What's actually in this capsule?
Just pumpkin seed (450 mg) and the capsule itself, which is made from gelatin and water. No extra fillers or binders.
I'm taking lithium for my mood. Can I use this?
Not without checking first. Pumpkin may reduce how quickly your body clears lithium, causing levels to rise. Your doctor or pharmacist may need to adjust your lithium dose, so contact them before starting this supplement.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pumpkin Seed 450 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pumpkin Seed 450 mg label
Go deeper

The Full Monographs Behind Pumpkin Seed 450 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Pumpkin Seed 450 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pumpkin 5 references
  1. Marks L, Partin AW, Epstein JI, et al. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol 2000;163:1451-6. DOI
  2. Cho YH, Lee SY, Jeong DW, et al. Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evid Based Complement Alternat Med 2014;2014:549721. PubMed
  3. Vahlensieck W, Theurer C, Pfitzer E, Patz B, Banik N, Engelmann U. Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urol Int 2015;94(3):286-95 PubMed
  4. Assouly P. Hair loss associated with cucurbit poisoning. JAMA Dermatol. 2018 May 1;154(5):617-618. PubMed
  5. Gawryjolek J, Ludwig H, Zbikowska-Götz M, Bartuzi Z, Krogulska A. Anaphylaxis after consumption of pumpkin seeds in a 2-y-old child tolerant to its pulp: A case study. Nutrition 2021;89:111272. PubMed

See these in context on the Pumpkin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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