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Dietary supplement

Pumpkin Seed Oil 1000 mg Ingredients & Drug Interactions

by NOW

Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Pumpkin Seed Oil 1000 mg is a dietary supplement by NOW with 1 active ingredient. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, overactive bladder, eye and skin health (vitamin a source).Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pumpkin Seed Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Pumpkin Seed Oil 1000 mg by NOW

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 3 active ingredients: pumpkin seed oil, plus polyunsaturated fat and monounsaturated fat. The pumpkin seed oil is the star — it's the concentrated oil from pumpkin seeds, and the fats it contains are what give it its potential health effects.

The capsule itself is made from gelatin, glycerin, and water, which are inactive ingredients that help deliver the oil.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: nutritional oil with essential fatty acids and phytosterols.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Overactive bladder.
  • The strongest evidence on file: Pumpkin is rated "Possibly Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Pumpkin is rated "Insufficient Reliable Evidence To Rate" for Overactive bladder.

The evidence for pumpkin seed oil is mixed. It's rated possibly effective for benign prostatic hyperplasia (BPH), the condition where an enlarged prostate causes urinary problems.

For other uses — androgenic alopecia (male pattern baldness), interstitial cystitis (bladder pain), parasitic infections, and urinary tract infections — the evidence isn't reliable enough to rate, so we can't say whether it works for those.

The evidence, ingredient by ingredient Pumpkin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pumpkin seed oil is generally well tolerated as a supplement in adults. The most common side effects seen in trials are mild — abdominal discomfort, diarrhea, nausea, and vomiting.

Anaphylaxis (a severe allergic reaction) is rare. There are also two case reports of transient hair loss after eating high-cucurbitacin pumpkin products (not typical ones), though this is uncommon.

Pregnancy and breastfeeding safety data isn't on file for this ingredient — talk to your doctor or pharmacist about whether it's right for you if you're pregnant or nursing.

Side effects, ingredient by ingredient Pumpkin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Pumpkin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take lithium, double-check with your pharmacist before starting this product — pumpkin seed oil may increase lithium levels (Moderate interaction). No other medication interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Pumpkin seed oil may help with benign prostatic hyperplasia, and it's generally well tolerated. The main caution: if you take lithium, check with your pharmacist before starting — this supplement could raise your lithium levels.

For pregnancy or breastfeeding, get personalized advice from your doctor.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pumpkin Seed Oil 1000 mg, straight from the product label.

Brand NOW
Barcode (UPC) 733739018434
Net contents 200 Softgel(s)
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 313998
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Halal, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pumpkin Seed Oil 1000 mg by NOW, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
100
UPC/BARCODE
733739018434
IngredientAmount% DV
Calories20 Calorie(s)--
Total Fat2 Gram(s)3%
Saturated Fat0.5 Gram(s)3%
Polyunsaturated Fat1 Gram(s)--
Monounsaturated Fat0.5 Gram(s)--
Pumpkin Seed Oil2 Gram(s)--

Other ingredients: Gelatin, Glycerin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: Take 2 softgels 1 to 2 times daily with food.

Formula

Pumpkin Seed Oil is a nutritional oil with essential fatty acids (EFAs) and phytosterols. NOW Pumpkin Seed Oil is cold pressed without the use of solvents, and derived only from the highest quality non-GMO pumpkin seeds.

Nutritional Oil Essential Fatty Acids and Phytosterols

Triangle K (Kosher) Contains Gelatin

Crescent H (Halal)

Formulation

NOW Pumpkin Seed Oil is cold pressed without the use of solvents and derived only from the highest quality non-GMO pumpkin seeds.

Natural color variation may occur in this product. Naturally occurring dark particulates may be visible in the pumpkin seed oil but do not affect the quality of the product.

Cold pressed

Non-GMO

Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish, shellfish or sesame ingredients.

Made and quality tested in the USA with globally sourced ingredients.

Precautions

Caution: For adults only. Keep out of reach of children.

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Triangle K (Kosher) Contains Gelatin

Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish, shellfish or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Seals/Symbols

Triangle K (Kosher) Contains Gelatin

GMP Quality Assured Crescent H (Halal)

FDA Statement of Identity

A Dietary Supplement

General Statements

Nutritional oils Family owned since 1968.

This bottle is made from 100% PCR (post-consumer recycled) resin.

Storage

Store in a cool, dry place after opening.

See for yourself

Pumpkin Seed Oil 1000 mg by NOW label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pumpkin Seed Oil 1000 mg by NOW

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container100 Amounts shown are per serving.

Pumpkin Seed Oil

Interacts with
1 drug
2 Gram(s) per serving Form: Cucurbita pepo

Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The...

Pumpkin Seed Oil monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pumpkin Seed Oil 1000 mg by NOW Drug Interactions

Want to check YOUR meds against Pumpkin Seed Oil 1000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Pumpkin Seed Oil 1000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Pumpkin Seed Oil1 drug type · 1 drug

Lithium

Pumpkin might reduce excretion and increase levels of lithium.
Pumpkin is thought to have diuretic properties. Theoretically, this might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Pumpkin Seed Oil 1000 mg, from the product label.

NOW

See all NOW products
Name
NOW FOODS
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Web Address
nowfoods.com
Pharmacist Counseling Corner

Pumpkin Seed Oil 1000 mg by NOW: Common Questions

Does Pumpkin Seed Oil 1000 mg by NOW interact with any medications?
Yes. Based on its ingredients, Pumpkin Seed Oil 1000 mg has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pumpkin Seed Oil 1000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help with my enlarged prostate?
Pumpkin seed oil is rated possibly effective for benign prostatic hyperplasia, so there's some evidence it may help. That said, talk to your doctor about whether it's right for you and how it fits with your other treatment.
What side effects should I watch for?
Most people tolerate it well. The most common side effects are mild — abdominal discomfort, diarrhea, nausea, or vomiting. Severe allergic reactions (anaphylaxis) are very rare. If you notice anything worrisome, stop and tell your pharmacist.
Is this safe to take while breastfeeding?
We don't have enough safety data on concentrated pumpkin seed oil supplements during breastfeeding. Talk to your doctor or pharmacist to decide whether it's okay for you.
Can I take this if I'm pregnant?
We don't have enough data to know whether concentrated pumpkin seed oil supplements are safe in pregnancy. Your doctor or pharmacist can give you personalized advice.
Does this help with hair loss?
The evidence for pumpkin seed oil and male pattern baldness isn't reliable enough for us to rate it, so we can't say whether it works. If you're interested in trying it, ask your doctor first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pumpkin Seed Oil 1000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pumpkin Seed Oil 1000 mg label
Go deeper

The Full Monographs Behind Pumpkin Seed Oil 1000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Pumpkin Seed Oil 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pumpkin 5 references
  1. Marks L, Partin AW, Epstein JI, et al. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol 2000;163:1451-6. DOI
  2. Cho YH, Lee SY, Jeong DW, et al. Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evid Based Complement Alternat Med 2014;2014:549721. PubMed
  3. Vahlensieck W, Theurer C, Pfitzer E, Patz B, Banik N, Engelmann U. Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urol Int 2015;94(3):286-95 PubMed
  4. Assouly P. Hair loss associated with cucurbit poisoning. JAMA Dermatol. 2018 May 1;154(5):617-618. PubMed
  5. Gawryjolek J, Ludwig H, Zbikowska-Götz M, Bartuzi Z, Krogulska A. Anaphylaxis after consumption of pumpkin seeds in a 2-y-old child tolerant to its pulp: A case study. Nutrition 2021;89:111272. PubMed

See these in context on the Pumpkin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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