No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Pygeum Africanum Extract Powder 5000 mg Ingredients & Drug Interactions

by BulkSupplements.com

Powder Category: Botanical
No known interaction
The interaction bottom line No known interaction

Pygeum Africanum Extract Powder 5000 mg is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, urinary symptoms in men, prostate health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Pygeum Africanum Extract Powder 5000 mg by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Pygeum africanum Bark Extract at 5000 mg per serving. Pygeum is an extract from the bark of an African tree, used traditionally for men's prostate health.

The powder also contains maltodextrin as an inactive ingredient to help with texture and handling.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Prostate health and urinary function.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Urinary symptoms, Prostate symptoms, Nocturia.
  • The strongest evidence on file: Pygeum is rated "Likely Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).

Pygeum shows likely effectiveness for benign prostatic hyperplasia (BPH) — the noncancerous enlargement of the prostate that can cause urinary symptoms in older men. For other uses listed in the research — Alzheimer disease, malaria, sexual desire, and psychosis — the evidence is insufficient to rate it either way.

The data we hold doesn't establish effectiveness for those conditions.

The evidence, ingredient by ingredient Pygeum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pygeum is generally well tolerated in short-term use, but quality and long-term safety data are limited. In clinical research, nausea and abdominal pain were reported by some participants, though at rates similar to placebo.

The safety data advises against use in pregnancy because it's intended for men's prostate health. There isn't enough safety information to recommend it while breastfeeding — talk with your pharmacist or doctor for personalized advice.

Side effects, ingredient by ingredient Pygeum

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for this ingredient. That doesn't mean none exist, so if you take any prescription medications, check them with the tool on this page or ask us before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

If you're a man looking at pygeum for prostate symptoms, the evidence supports trying it short-term — just know that long-term safety data are thin. Check your medications before you start, especially if you take anything for your prostate or blood pressure.

Your pharmacist can help you weigh whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pygeum Africanum Extract Powder 5000 mg, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X001R0FJYZ
Net contents 100 Gram(s); 3.5 Ounce(s)
Market status On market
Date entered into DSLD Apr 24, 2025
DSLD ID 330382
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pygeum Africanum Extract Powder 5000 mg by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5000 Milligram(s)
Maximum serving Sizes:
5000 Milligram(s)
Servings per container
20
UPC/BARCODE
X001R0FJYZ
IngredientAmount% DV
Pygeum africanum Bark Extract5000 mg--

Other ingredients: Maltodextrin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Pygeum Africanum Extract Powder 5000 mg per serving

Brand IP Statement(s)

Bulksupplements.com Clean & pure bulk supplements

Formulation

Color may vary

Free of: Added sugar, soy, dairy, yeast, gluten

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 5000 mg (about 2 tsp) once daily with meals, or as directed by a physician.

Storage

Contents are sold by weight, not volume. Settling may occur. Store in a dry, cool place

General Statements

Use an accurate milligram scale. New

See for yourself

Pygeum Africanum Extract Powder 5000 mg by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pygeum Africanum Extract Powder 5000 mg by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size5000 Milligram(s) Dosage formPowder Servings per container20 Amounts shown are per serving.

Pygeum africanum Bark Extract

No known
interactions
5000 mg per serving

Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some st...

Pygeum africanum Bark Extract monograph & interactions

Other (inactive) ingredients: Maltodextrin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pygeum Africanum Extract Powder 5000 mg by BulkSupplements.com Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Pygeum Africanum Extract Powder 5000 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Pygeum Africanum Extract Powder 5000 mg, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

Pygeum Africanum Extract Powder 5000 mg by BulkSupplements.com: Common Questions

Does Pygeum Africanum Extract Powder 5000 mg by BulkSupplements.com interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Pygeum Africanum Extract Powder 5000 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Pygeum Africanum Extract Powder 5000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does pygeum really help with prostate symptoms?
Yes, pygeum shows likely effectiveness for benign prostatic hyperplasia — the noncancerous swelling of the prostate that causes trouble with urination. That's the main use where the research backs it up.
What side effects should I watch for?
Nausea and abdominal pain have been reported in some people taking pygeum, but in the clinical trials we have data on, they occurred at about the same rate as placebo. Most people tolerate it well short-term.
How long can I safely take this?
Pygeum is generally well tolerated in the short term, but the quality and long-term safety data are limited. If you're thinking of using it long-term, check with your pharmacist about what we actually know.
Is this safe during pregnancy or breastfeeding?
The safety data advises against use in pregnancy since pygeum is intended for men's prostate health. There also isn't enough safety information to recommend it while breastfeeding — talk with your doctor or pharmacist for personalized guidance.
What does this powder contain besides the active ingredient?
The only other ingredient is maltodextrin, an inactive ingredient used to help with the powder's texture and handling.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pygeum Africanum Extract Powder 5000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pygeum Africanum Extract Powder 5000 mg label
Go deeper

The Full Monographs Behind Pygeum Africanum Extract Powder 5000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Pygeum Africanum Extract Powder 5000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pygeum 3 references
  1. Ishani A, MacDonald R, Nelson D, et al. Pygeum africanum for the treatment of patients with benign prostatic hyperplasia: a systematic review and quantitative meta-analysis. Am J Med 2000;109:654-64.. PubMed
  2. Wilt T, Ishani A, Mac Donald R, et al. Pygeum africanum for benign prostatic hyperplasia. Cochrane Database Syst Rev 2002;CD001044.. PubMed
  3. Andro M and Riffaud J. Pygeum africanum extract for the treatment of patients with benign prostatic hyperplasia: a review of 25 years of published experience. Curr Ther Res 1995;56(8):796-817. DOI

See these in context on the Pygeum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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