No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Pygeum Bark 500 mg Ingredients & Drug Interactions

by Indiana Botanic Gardens

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Pygeum Bark 500 mg is a dietary supplement by Indiana Botanic Gardens with 1 active ingredient. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, urinary symptoms in men, prostate health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Pygeum Bark 500 mg by Indiana Botanic Gardens

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: pygeum africanum powder at 500 mg per capsule. Pygeum comes from the bark of an African tree and has been used traditionally for prostate and urinary health.

The capsule itself is made of gelatin, microcrystalline cellulose (a binder), and magnesium stearate (a flow agent).

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Prostate support.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Urinary symptoms, Prostate health.
  • The strongest evidence on file: Pygeum is rated "Likely Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).

Pygeum is likely effective for benign prostatic hyperplasia (BPH) — the noncancerous prostate enlargement that can cause urinary symptoms in older men. For other uses listed in the literature — including Alzheimer disease, malaria, and sexual desire — the evidence we hold is insufficient to rate whether it works.

The evidence, ingredient by ingredient Pygeum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pygeum is generally well tolerated in short-term use, though quality and long-term safety data are limited. In clinical trials, nausea and abdominal pain occurred in some participants at rates similar to placebo.

Pygeum is used for men's prostate health and has no established safe use in pregnancy. There isn't enough safety information to recommend it while breastfeeding.

If you're pregnant, planning pregnancy, or nursing, talk with your doctor or pharmacist before taking it.

Side effects, ingredient by ingredient Pygeum

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for pygeum africanum powder. That said, always run your complete medication list through the checker on this page or talk with your pharmacist before starting any new supplement.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Pygeum Bark may help men manage benign prostate enlargement and urinary symptoms. It's generally tolerated well short-term, though long-term data are sparse.

Before you start, check your medications with your pharmacist or doctor — and if you're pregnant, breastfeeding, or planning pregnancy, discuss it with them first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 21, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pygeum Bark 500 mg, straight from the product label.

Brand Indiana Botanic Gardens
Barcode (UPC) 703308029314
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Sep 21, 2017
DSLD ID 78845
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pygeum Bark 500 mg by Indiana Botanic Gardens, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
703308029314
IngredientAmount% DV
Pygeum africanum powder500 mg--

Other ingredients: Gelatin Capsule, Microcrystalline Cellulose, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Prostate support

FDA Statement of Identity

Herbal supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 capsule twice daily, with a meal, as a dietary supplement, or as directed by a physician.

Precautions

Warning: If you are taking any medications or are pregnant or nursing do not use prior to consulting a physician.

For your protection, this container has an outer safety seal. (Do not accept if missing or broken.)

Keep out of reach of children

FDA Disclaimer Statement

This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Store in a dry, cool place.

Brand IP Statement(s)

IBG Indiana Botanic Gardens

See for yourself

Pygeum Bark 500 mg by Indiana Botanic Gardens label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pygeum Bark 500 mg by Indiana Botanic Gardens

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Pygeum africanum powder

No known
interactions
500 mg per serving

Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some st...

Pygeum africanum powder monograph & interactions

Other (inactive) ingredients: Gelatin Capsule, Microcrystalline Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pygeum Bark 500 mg by Indiana Botanic Gardens Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Pygeum Bark 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Pygeum Bark 500 mg, from the product label.

Indiana Botanic Gardens

See all Indiana Botanic Gardens products
Name
Indiana Botanic Gardens, Inc.
Street Address
3401 W. 37th Ave.
City
Hobart
State
IN
ZipCode
46342
Phone Number
1-800-644-8327
Web Address
www.botanicchoice.com
Pharmacist Counseling Corner

Pygeum Bark 500 mg by Indiana Botanic Gardens: Common Questions

Does Pygeum Bark 500 mg by Indiana Botanic Gardens interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Pygeum Bark 500 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Pygeum Bark 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is pygeum used for?
Pygeum is likely effective for benign prostatic hyperplasia (BPH) — noncancerous prostate enlargement — which often causes urinary symptoms in older men. It's also been studied for Alzheimer disease, malaria, and sexual desire, but evidence for those uses isn't established in the data we hold.
Does pygeum cause side effects?
Nausea and abdominal pain were reported in some clinical trial participants, but they occurred at about the same rate as placebo. Pygeum is generally well tolerated short-term, though we don't have much long-term safety data.
Can I take pygeum if I'm pregnant or breastfeeding?
Pygeum has no established safe use in pregnancy and isn't recommended while breastfeeding because there isn't enough safety information. Talk with your doctor or pharmacist before taking it if you're pregnant, planning pregnancy, or nursing.
How much pygeum is in each capsule?
Each capsule contains 500 mg of pygeum africanum powder.
What are the inactive ingredients?
The capsule is made of gelatin, microcrystalline cellulose (a binder), and magnesium stearate (a flow agent).

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pygeum Bark 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pygeum Bark 500 mg label
Go deeper

The Full Monographs Behind Pygeum Bark 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Pygeum Bark 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pygeum 3 references
  1. Ishani A, MacDonald R, Nelson D, et al. Pygeum africanum for the treatment of patients with benign prostatic hyperplasia: a systematic review and quantitative meta-analysis. Am J Med 2000;109:654-64.. PubMed
  2. Wilt T, Ishani A, Mac Donald R, et al. Pygeum africanum for benign prostatic hyperplasia. Cochrane Database Syst Rev 2002;CD001044.. PubMed
  3. Andro M and Riffaud J. Pygeum africanum extract for the treatment of patients with benign prostatic hyperplasia: a review of 25 years of published experience. Curr Ther Res 1995;56(8):796-817. DOI

See these in context on the Pygeum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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