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Dietary supplement

REL Super Chlorella Ingredients & Drug Interactions

by Systemic Formulas Bio Nutriment

REL Super Chlorella label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking REL Super Chlorella against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

REL Super Chlorella is a dietary supplement by Systemic Formulas Bio Nutriment with 1 active ingredient. Its ingredients are commonly taken for general nutrition and 'detox' support, immune support, liver and kidney support.Based on those ingredients, 337 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chlorella. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against REL Super Chlorella by Systemic Formulas Bio Nutriment

Ask about any prescription or over-the-counter medication and we check it for interactions with REL Super Chlorella by Systemic Formulas Bio Nutriment — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of REL Super Chlorella by Systemic Formulas Bio Nutriment

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

REL Super Chlorella is a one-ingredient product: chlorella, a freshwater algae. The capsule also contains gelatin as an inactive ingredient.

Chlorella is a nutrient-dense green algae used in supplements for its protein, vitamins, minerals, and other compounds. This product contains it as a dried powder in capsule form.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Chlorella's overall clinical evidence instead.

Moderate

Some clinical evidence supports Chlorella for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Pregnancy-related iron deficiency — rated "Possibly Effective" (Natural Medicines).

The evidence we hold shows chlorella is possibly effective for pregnancy-related iron deficiency. For brain tumor, nonalcoholic fatty liver disease (NAFLD), depression, and fatigue, the evidence is insufficient to rate — meaning we don't yet have reliable data one way or the other.

If you're considering this for any of those uses, talk with your doctor about what the current science supports and whether it makes sense for your situation.

The evidence, ingredient by ingredient Chlorella

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chlorella is generally well tolerated over the short term, though product quality and purity vary widely between brands — that's important to know. The most common side effects are allergic reactions, abdominal cramping, constipation, diarrhea, fatigue, gas, nausea, photosensitivity, and stool discoloration.

These tend to show up early, especially in the first two weeks. Rare serious effects include anaphylaxis (a severe allergic reaction).

There isn't enough safety data to recommend chlorella unless your doctor approves it. If you're pregnant, the data suggests it's possibly safe, but that's not a guarantee — talk with your doctor or pharmacist for personalized advice.

For breastfeeding, we don't have enough data either way — again, check with your healthcare provider.

Side effects, ingredient by ingredient Chlorella

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Chlorella.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 337 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you're on warfarin (Coumadin) or any photosensitizing drugs. Both are Moderate-severity interactions — chlorella's vitamin K can weaken warfarin's effect, and chlorella itself can make your skin more sun-sensitive, especially if you're already taking a drug with that risk.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

REL Super Chlorella may be worth considering if you have pregnancy-related iron deficiency and your doctor thinks it's appropriate. If you take warfarin or any photosensitizing medication, you'll need to check with your doctor or pharmacist first — the interactions are real.

Quality varies between brands, so sourcing matters. Run your full medication list through the checker on this page and talk it over with your own healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about REL Super Chlorella, straight from the product label.

Brand Systemic Formulas Bio Nutriment
Barcode (UPC) 635585018012
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jun 25, 2013
DSLD ID 22049
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for REL Super Chlorella by Systemic Formulas Bio Nutriment, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
UPC/BARCODE
635585018012
IngredientAmount% DV
Chlorella940 mg--

Other ingredients: Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Keep away from Heat, Sunlight and Children.

General

#180 H/11

General Statements

Supports overall body systems; helps to stabilize general cleansing and to maintain a healthy immune system.

SOLD THROUGH PROFESSIONALS

MADE IN U.S.A.

A special micro-mill cracking process is used to maximize the ease of digestion and assimilation of nutrients in Chlorella 1000.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any diseases.

Suggested/Recommended/Usage/Directions

DIRECTIONS FOR NUTRITIONAL USE: 1-2 capsules up to twice a day for 1-3 months, or as directed. Then take as needed for maintenance. Increase the amount of liquids you drink each day while taking this product.

FDA Statement of Identity

Dietary Supplement

Storage

Keep away from Heat, Sunlight and Children.

Formula

Each capsule contains 470 mg of pure, active Chlorella completly free of any additives.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

REL Super Chlorella by Systemic Formulas Bio Nutriment label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

REL Super Chlorella label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in REL Super Chlorella by Systemic Formulas Bio Nutriment

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Chlorella

Interacts with
337 drugs
940 mg per serving

Chlorella is a nutrient-rich freshwater green algae taken as a supplement for general wellness, immune support, and 'detox.' Some small studies sugges...

Chlorella monograph & interactions

Other (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

REL Super Chlorella by Systemic Formulas Bio Nutriment Drug Interactions

Want to check YOUR meds against REL Super Chlorella?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
337Drugs
337 Moderate

Ingredients driving the most interactions

Chlorella 337

Individual Drug Interactions

The ingredients in REL Super Chlorella interact with 337 drugs. Click any drug to see the details.

1 of the 1 ingredient in REL Super Chlorella interact with drugs. Each result below shows which ingredient is responsible. Chlorella

Each ingredient & the kinds of drugs it affects

For each ingredient in REL Super Chlorella with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Chlorella2 drug types · 337 drugs

Photosensitizing Drugs

Theoretically, chlorella might have additive effects with photosensitizing drugs.
Chlorella has been reported to cause photosensitization. In five case reports, patients who had ingested chlorella exhibited swelling followed by erythematopurpuric lesions on sun-exposed areas of the body. Theoretically, concomitant use with photosensitizing drugs may exacerbate effects.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, chlorella might reduce the clinical effects of warfarin.
Chlorella contains significant amounts of vitamin K. There is at least one case report of warfarin therapy becoming sub-therapeutic after initiation of chlorella supplements.

Likelihood Possible Evidence D
Chlorella full monograph & interactions
The maker

Brand information

Manufacturer and brand details for REL Super Chlorella, from the product label.

Systemic Formulas Bio Nutriment

See all Systemic Formulas Bio Nutriment products
Name
Systemic Formulas Inc.
Street Address
P.O.Box 1516
City
Ogden
State
UT
ZipCode
84402
Web Address
www.systemicformulas.com
Pharmacist Counseling Corner

REL Super Chlorella by Systemic Formulas Bio Nutriment: Common Questions

Does REL Super Chlorella by Systemic Formulas Bio Nutriment interact with any medications?
Yes. Based on its ingredients, REL Super Chlorella has a known interaction with 337 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
REL Super Chlorella contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will chlorella interact with my warfarin?
Possibly, yes — it's a documented Moderate-severity interaction. Chlorella is high in vitamin K, which can reduce how well warfarin (a blood thinner) works. There's at least one case report of this happening. Talk with your doctor or pharmacist before adding it; they may need to monitor you more closely or adjust your dose.
Can I take this if I'm pregnant?
The data suggests it's possibly safe in pregnancy, but that's not the same as a guarantee, and we don't have complete information. Talk with your doctor or pharmacist for advice tailored to your situation.
What are the most common side effects?
Allergic reactions, stomach cramping, constipation, diarrhea, fatigue, gas, nausea, photosensitivity (sun sensitivity), and stool discoloration. Most show up early, especially in the first two weeks. Anaphylaxis is rare but serious.
Does chlorella really work for iron deficiency in pregnancy?
Chlorella is possibly effective for pregnancy-related iron deficiency based on the evidence we hold. For other uses listed here — depression, fatigue, liver disease, brain tumors — the evidence is still insufficient to know. Your doctor can help you weigh whether it's right for your specific need.
Why do you mention product quality and purity vary widely?
Because chlorella comes from different sources and manufacturers, and testing standards aren't uniform across brands. What you're actually getting can differ from one product to the next, so sourcing and third-party testing matter.
Will this cause photosensitivity?
Chlorella can cause photosensitivity — cases have been reported of patients on chlorella developing swelling and rash on sun-exposed skin. This risk is worse if you're also on a photosensitizing drug. Be extra careful with sun exposure, and talk with your doctor if you're on that type of medication.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if REL Super Chlorella is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

REL Super Chlorella label
Go deeper

The Full Monographs Behind REL Super Chlorella’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Chlorella

Interacts with 337 drugs

Chlorella is a nutrient-rich freshwater green algae taken as a supplement for general wellness, immune support, and 'detox.' Some small studies suggest possible benefits for cholesterol, blo...

Read the full Chlorella monograph →
Sources

Sources & How We Checked

REL Super Chlorella's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 13 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Chlorella 13 references
  1. Peirce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York, NY: William Morrow and Co., 1999.
  2. Ng TP, Tan WC, Lee YK. Occupational asthma in a pharmacist induced by chlorella, a unicellular algae preparation. Resp Med 1994;88:555-7. PubMed
  3. Jitsukawa K, Suizu R, Hidano A. Chlorella photosensitization. New phytophotodermatosis. Int J Dermatol 1984;23:263-8. PubMed
  4. Merchant RE, Carmack CA, Wise CM. Nutritional supplementation with Chlorella pyrenoidosa for patients with fibromyalgia syndrome: a pilot study. Phytother Res 2000;14:167-73.
  5. Merchant RE, Rice CD, Young HF. Dietary Chlorella pyrenoidosa for patients with malignant glioma: effects on immunocompetence, quality of life, and survival. Phytother Res 1990;4:220-31.
  6. Halperin SA, Smith B, Nolan C, et al. Safety and immunoenhancing effect of a Chlorella-derived dietary supplement in healthy adults undergoing influenza vaccination: randomized, double-blind, placebo-controlled trial. CMAJ 2003;169:111-7..
  7. Ohtake, T., Negishi, K., Okamoto, K., Oka, M., Maesato, K., Moriya, H., and Kobayashi, S. Manganese-induced Parkinsonism in a patient undergoing maintenance hemodialysis. Am J Kidney Dis 2005;46(4):749-753. PubMed
  8. Ng, T. P., Tan, W. C., and Lee, Y. K. Occupational asthma in a pharmacist induced by Chlorella, a unicellular algae preparation. Respir.Med. 1994;88(7):555-557. PubMed
  9. Ohkawa, S., Yoneda, Y., Ohsumi, Y., and Tabuchi, M. [Warfarin therapy and chlorella]. Rinsho Shinkeigaku 1995;35(7):806-807.
  10. Azocar J, Diaz A. Efficacy and safety of chlorella supplementation in adults with chronic hepatitis C virus infection. World J Gastroenterol 2013;19(7):1085-90. PubMed
  11. Panahi Y, Badeli R, Karami GR, Badeli Z, Sahebkar A. A randomized controlled trial of 6-week Chlorella vulgaris supplementation in patients with major depressive disorder. Complement Ther Med 2015;23(4):598-602. PubMed
  12. Nakano S, Takekoshi H, Nakano M. Chlorella pyrenoidosa supplementation reduces the risk of anemia, proteinuria and edema in pregnant women. Plant Foods Hum Nutr 2010;65(1):25-30. PubMed
  13. Yavasoglu I, Turgutkaya A, Bolaman Z. Chlorella-induced thrombocytopenia. Sao Paulo Med J 2018;136(6):602-3. PubMed

See these in context on the Chlorella monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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