Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Saffron Lift + Curcumin Ingredients & Drug Interactions

by Terry Naturally

Saffron Lift + Curcumin label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Saffron Lift + Curcumin against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Saffron Lift + Curcumin is a dietary supplement by Terry Naturally with 2 active ingredients. Its ingredients are commonly taken for depression and low mood, anxiety, pms symptoms.Based on those ingredients, 521 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are EP15. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Saffron Lift + Curcumin by Terry Naturally

Ask about any prescription or over-the-counter medication and we check it for interactions with Saffron Lift + Curcumin by Terry Naturally — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Saffron Lift + Curcumin by Terry Naturally

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • “BCM-95 Curcugreen” is listed as a grouped ingredient — the label gives one combined amount (250 mg) without saying how much of each component you get.

Saffron Lift + Curcumin contains two active ingredients: saffron extract (EP15) and a curcumin blend (BCM-95 Curcugreen), which is a processed form that includes turmeric compounds for better absorption. The product also holds several inactive ingredients — hydroxypropyl methylcellulose, maltodextrin, magnesium stearate, and silica — which are fillers and capsule materials that don't add therapeutic effect.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Saffron's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: mood support and stress management.
  • We looked for evidence on: Anxiety, Insomnia, Postpartum depression, Premenstrual dysphoric disorder (PMDD), Premenstrual syndrome (PMS), depression — and 2 related terms.
  • The closest evidence on file: Saffron is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: Saffron is rated "Insufficient Reliable Evidence To Rate" for Postpartum depression, Insomnia, Premenstrual dysphoric disorder (PMDD), Premenstrual syndrome (PMS).

Saffron has possibly effective evidence for two conditions: chemotherapy-induced peripheral neuropathy (nerve pain after cancer treatment) and Alzheimer disease. That means some clinical trials suggest benefit, but the evidence isn't yet strong enough to call it proven.

We hold no effectiveness data on file for the curcumin component of this product.

The evidence, ingredient by ingredient Saffron

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Saffron at supplement doses should be used carefully — it's considered likely safe in food amounts, but higher supplement doses can be toxic. The most common side effects from oral saffron are gastrointestinal complaints, nausea, sedation, and vomiting.

Rare but serious allergic reactions, including anaphylaxis, have been reported; if you've ever had an allergy to saffron or occupational exposure caused breathing problems, talk with your pharmacist before trying this product. At higher doses (30 mg twice daily for 26 weeks), some people reported anxiety and mood changes.

We don't have safety data on file for the curcumin ingredient in this product. Saffron should be avoided in pregnancy, as the safety data advises against medicinal or supplement amounts because it may stimulate the uterus.

There isn't enough reliable safety information for breastfeeding — talk with your doctor or pharmacist about whether this product is right for you if you're nursing.

Side effects, ingredient by ingredient Saffron

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Saffron.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 521 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before starting this product, check with your pharmacist if you take CNS depressants (sleep aids, sedatives, anti-anxiety medications, opioids) — saffron may add to drowsiness. Also double-check if you're on blood pressure medications, diabetes medications, or use caffeine regularly, as saffron may intensify all three.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product may be worth considering if you're dealing with nerve pain after chemotherapy or interested in Alzheimer support, though evidence is modest. If you take any blood pressure medication, diabetes medication, sleep aids, or rely on caffeine, check with your pharmacist first — saffron can intensify their effects.

Steer clear if you're pregnant or have a known saffron allergy.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Saffron Lift + Curcumin, straight from the product label.

Brand Terry Naturally
Barcode (UPC) 367703185464
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Mar 25, 2025
DSLD ID 325765
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Saffron Lift + Curcumin by Terry Naturally, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
367703185464
IngredientAmount% DV
BCM-95 Curcugreen250 mg--
Curcuminoids, Pure215 mg--
EP1515 mg--

Other ingredients: Hydroxypropyl Methylcellulose, Maltodextrin, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Money-Back Guarantee Give your mood a lift Powerful, clinical strength Saffron Lift helps you rediscover feelings of happiness every day. Positive state of mind Healthy Responses to stress Occasional stress Restful sleep Healthy serotonin, cortisol and GABA levels

Vegan

Non-GMO

Positive Mood | Emotional Balance

No sugar, salt, yeast, wheat, gluten, corn, soy, dairy products, artificial coloring, artificial flavoring, or artificial preservatives.

Suggested/Recommended/Usage/Directions

Recommendations: Take 1 capsule twice daily.

Precautions

If pregnant or nursing, consult a healthcare practitioner before using.

Seals/Symbols

Lab Tested for Purity & Quality

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Clinically studied Curcumin with Turmerones

General Statements

For Your Good Health Terry

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Saffron Lift + Curcumin by Terry Naturally label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Saffron Lift + Curcumin label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Saffron Lift + Curcumin by Terry Naturally

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

BCM-95 Curcugreen

250 mg per serving Form: Curcumin, Curcuminoid Complex, Turmeric essential Oil
  • › Curcuminoids, Pure

EP15

Interacts with
521 drugs
15 mg per serving Form: Saffron Stigma Extract

Saffron is a costly spice that has shown promise in early studies for mild-to-moderate depression and some mood and PMS symptoms, but most research us...

EP15 monograph & interactions

Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Maltodextrin, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Saffron Lift + Curcumin by Terry Naturally Drug Interactions

Want to check YOUR meds against Saffron Lift + Curcumin?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
521Drugs
521 Moderate

Ingredients driving the most interactions

EP15 521

Individual Drug Interactions

The ingredients in Saffron Lift + Curcumin interact with 521 drugs. Click any drug to see the details.

1 of the 2 ingredients in Saffron Lift + Curcumin interact with drugs. Each result below shows which ingredient is responsible. EP15

Each ingredient & the kinds of drugs it affects

For each ingredient in Saffron Lift + Curcumin with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

EP154 drug types · 521 drugs

Antidiabetes Drugs

Theoretically, concomitant use of saffron with antidiabetes drugs might increase the risk of hypoglycemia.
Some clinical research shows that taking saffron extract reduces fasting levels of glucose when used in addition to hypoglycemic agents. However, saffron powder itself has not been shown to reduce fasting glucose levels.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, concomitant use of saffron with antihypertensive drugs might have additive effects.
Animal and human research suggests that saffron extract can decrease blood pressure.

Likelihood Possible Evidence D
Caffeine

Theoretically, saffron might inhibit the metabolism of caffeine.
A small clinical study suggests that taking saffron powder 300 mg in 150 mL water daily for 5 days and then taking caffeine 200 mg seems to reduce caffeine metabolite levels in the saliva and urine in males, but not females. Theoretically, this may be due to the inhibition of cytochrome P450 1A2 by saffron.

Likelihood Possible Evidence B
Cns Depressants

Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Clinical research shows that taking saffron extract 60 mg orally daily for 26 weeks can cause drowsiness and sedation. Animal research suggests that adding saffron to hexobarbital further increases sleeping and slows motor activity.

Likelihood Possible Evidence D
EP15 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Saffron Lift + Curcumin, from the product label.

Terry Naturally

See all Terry Naturally products
Name
EuroPharma, Inc.
City
Green Bay
State
WI
ZipCode
54311
Phone Number
(866) 807-2731
Web Address
EuroPharmaUSA.com
Pharmacist Counseling Corner

Saffron Lift + Curcumin by Terry Naturally: Common Questions

Does Saffron Lift + Curcumin by Terry Naturally interact with any medications?
Yes. Based on its ingredients, Saffron Lift + Curcumin has a known interaction with 521 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Saffron Lift + Curcumin contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is saffron, and what does it do in this product?
Saffron is a spice extracted from the crocus flower. In this product, the saffron extract (called EP15) is included because clinical research suggests it may help with nerve pain from chemotherapy and possibly support brain health in Alzheimer disease, though evidence is still building. Saffron can also cause drowsiness at supplement doses.
Can I take this if I'm pregnant or breastfeeding?
No — avoid saffron in supplement amounts during pregnancy, as the safety data advises against it because it may stimulate the uterus. If you're breastfeeding, there isn't enough reliable safety information to know either way, so talk with your doctor or pharmacist for personalized advice.
What are the most common side effects?
The most common side effects from saffron are stomach complaints, nausea, sedation (drowsiness), and vomiting. These were generally well tolerated in clinical trials, but at higher doses, some people reported anxiety and mood changes.
Is there any risk of an allergic reaction?
Yes — allergies to saffron have been reported, and in rare cases, anaphylaxis (a serious allergic reaction) can occur within minutes of consuming saffron. If you've had an allergy to saffron before or breathing problems from occupational saffron exposure, avoid this product and talk with your pharmacist.
Will this interact with my diabetes or blood pressure medication?
Possibly. Saffron may lower your blood pressure further if you're already on blood pressure medication, and it may increase the risk of low blood sugar if you take diabetes drugs. Talk with your pharmacist before starting, especially if you're already on either type of medication.
Does this contain any fillers?
Yes — the product contains inactive ingredients including hydroxypropyl methylcellulose, maltodextrin, magnesium stearate, and silica, which are typical binders and flow agents in capsule products.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Saffron Lift + Curcumin is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Saffron Lift + Curcumin label
Go deeper

The Full Monographs Behind Saffron Lift + Curcumin’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Saffron

Interacts with 521 drugs

Saffron is a costly spice that has shown promise in early studies for mild-to-moderate depression and some mood and PMS symptoms, but most research uses small trials, so results are not defi...

Read the full Saffron monograph →
Sources

Sources & How We Checked

Saffron Lift + Curcumin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 22 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Saffron 22 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  4. Feo F, Martinez J, Martinez A, et al. Occupational allergy in saffron workers. Allergy 1997;52:633-41. PubMed
  5. Wuthrich B, Schmid-Grendelmeyer P, Lundberg M. Anaphylaxis to saffron. Allergy 1997;52:476-7. PubMed
  6. Akhondzadeh S, Tahmacebi-Pour N, Noorbala AA, et al. Crocus sativus L. in the treatment of mild to moderate depression: a double-blind, randomized and placebo-controlled trial. Phytother Res 2005;19:148-51.
  7. Safarinejad MR, Shafiei N, Safarinejad S. A prospective double-blind randomized placebo-controlled study of the effect of saffron (Crocus sativus Linn.) on semen parameters and seminal plasma antioxidant capacity in infertile men with idiopathic oligoasth
  8. Fatehi, M., Rashidabady, T., and Fatehi-Hassanabad, Z. Effects of Crocus sativus petals' extract on rat blood pressure and on responses induced by electrical field stimulation in the rat isolated vas deferens and guinea-pig ileum. J Ethnopharmacol. 2003; PubMed
  9. Modaghegh, M. H., Shahabian, M., Esmaeili, H. A., Rajbai, O., and Hosseinzadeh, H. Safety evaluation of saffron (Crocus sativus) tablets in healthy volunteers. Phytomedicine. 2008;15(12):1032-1037. PubMed
  10. Imenshahidi, M., Hosseinzadeh, H., and Javadpour, Y. Hypotensive effect of aqueous saffron extract (Crocus sativus L.) and its constituents, safranal and crocin, in normotensive and hypertensive rats. Phytother.Res 12-9-2009;
  11. Zhang, Y., Shoyama, Y., Sugiura, M., and Saito, H. Effects of Crocus sativus L. on the ethanol-induced impairment of passive avoidance performances in mice. Biol.Pharm Bull. 1994;17(2):217-221. PubMed
  12. Wuthrich, B., Schmid-Grendelmeyer, P., and Lundberg, M. Anaphylaxis to saffron. Allergy 1997;52(4):476-477. PubMed
  13. Akhondzadeh S, Sabet MS, Harirchian MH, Togha M, Cheraghmakani H, Razeghi S, Hejazi SSh, Yousefi MH, Alimardani R, Jamshidi A, Zare F, Moradi A. Saffron in the treatment of patients with mild to moderate Alzheimer's disease: a 16-week, randomized and plac
  14. Kashani L, Eslatmanesh S, Saedi N, Niroomand N, Ebrahimi M, Hosseinian M, Foroughifar T, Salimi S, Akhondzadeh S. Comparison of Saffron versus Fluoxetine in Treatment of Mild to Moderate Postpartum Depression: A Double-Blind, Randomized Clinical Trial. Ph PubMed
  15. Kianbakht S, Ghazavi A. Immunomodulatory effects of saffron: a randomized double-blind placebo-controlled clinical trial. Phytother Res. 2011 Dec;25(12):1801-5. PubMed
  16. Mazidi M, Shemshian M, Mousavi SH, Norouzy A, Kermani T, Moghiman T, Sadeghi A, Mokhber N, Ghayour-Mobarhan M, Ferns GA. A double-blind, randomized and placebo-controlled trial of Saffron (Crocus sativus L.) in the treatment of anxiety and depression. J C
  17. Safarinejad MR, Shafiei N, Safarinejad S. An open label, randomized, fixed-dose, crossover study comparing efficacy and safety of sildenafil citrate and saffron (Crocus sativus Linn.) for treating erectile dysfunction in men naïve to treatment. Int J Impo PubMed
  18. Talaei A, Hassanpour Moghadam M, Sajadi Tabassi SA, Mohajeri SA. Crocin, the main active saffron constituent, as an adjunctive treatment in major depressive disorder: a randomized, double-blind, placebo-controlled, pilot clinical trial. J Affect Disord. 2 PubMed
  19. Azimi P, Ghiasvand R Feizi A, Hariri M, Abbasi B. Effects of cinnamon, cardamom, saffron, and ginger consumption on markers of glycemic control, lipid profile, oxidative stress, and inflammation in type 2 diabetes. Rev Diabet Stud. 2014 Fall-Winter;11(3-4
  20. Begas E, Bounitsi M, Kilindris T, et al. Effects of short-term saffron (Crocus sativus L.) intake on the in vivo activities of xenobiotic metabolizing enzymes in healthy volunteers. Food Chem Toxicol. 2019;130:32-43. PubMed
  21. Moravej Aleali A, Amani R, Shahbazian H, Namjooyan F, Latifi SM, Cheraghian B. The effect of hydroalcoholic Saffron (Crocus sativus L.) extract on fasting plasma glucose, HbA1c, lipid profile, liver, and renal function tests in patients with type 2 diabet
  22. Abbaszadeh-Mashkani S, Hoque SS, Banafshe HR, Ghaderi A. The effect of crocin (the main active saffron constituent) on the cognitive functions, craving, and withdrawal syndrome in opioid patients under methadone maintenance treatment. Phytother Res. 2021; PubMed

See these in context on the Saffron monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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