No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 3 of 11 ingredients. Check your meds →
Dietary supplement

SpectraZyme Complete Ingredients & Drug Interactions

by Metagenics

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

SpectraZyme Complete is a dietary supplement by Metagenics with 11 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of SpectraZyme Complete by Metagenics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 11 active ingredients.
  • “Proprietary Complete Enzyme Blend” is a proprietary blend — the label gives one combined amount (271 mg) without saying how much of each component you get.

SpectraZyme Complete is a blend of 11 digestive enzymes designed to support nutrient breakdown and absorption. The formula includes amylase (breaks down carbohydrates), lipase (breaks down fats), lactase (breaks down milk sugar), proteases (break down protein), cellulase, invertase, xylanase, pectinase, hemicellulase, and acid protease.

The inactive ingredients are a capsule, maltodextrin, and medium-chain triglycerides (filler and carrier ingredients).

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: broad spectrum digestive support.
  • We looked for evidence on: Dyspepsia, Lactose intolerance, indigestion, bloating, fat malabsorption, carbohydrate intolerance.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

Lactase in this formula is effective for lactose intolerance. The other enzyme ingredients—lipase, acid protease, protease fungal, and neutral protease—have insufficient reliable evidence to rate their effectiveness for digestive support, inflammatory bowel disease, or dyspepsia.

We hold no effectiveness data for the remaining enzymes (amylase, cellulase, invertase, xylanase, pectinase, and hemicellulase) in the product facts.

The evidence, ingredient by ingredient Lipase Lactase Proteolytic Enzymes (proteases)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The digestive enzymes in SpectraZyme Complete are generally well tolerated for most adults. Some people may experience mild digestive upset or allergic reactions, especially those with occupational exposure to protease powders.

Lactase can rarely trigger allergic reactions in sensitive individuals. If you have serious digestive conditions, use only under medical guidance.

During pregnancy, safety data is limited for lipase and the proteases—check with your doctor before regular use. Limited data exists for breastfeeding as well; ask your doctor or pharmacist first.

Side effects, ingredient by ingredient Lipase Lactase Proteolytic Enzymes (proteases)

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 3 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Run your exact medications through the interaction search tool on this page to be certain, and ask your doctor or pharmacist if you have questions before you start.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

SpectraZyme Complete is a digestive enzyme blend best suited for people looking to support nutrient breakdown, especially those with lactose intolerance. If you have a serious digestive disorder or are pregnant or breastfeeding, talk with your doctor or pharmacist before starting.

No medication interactions are documented for the ingredients we could check, but confirm with your own pharmacist that it's right for your specific medications and health.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about SpectraZyme Complete, straight from the product label.

Brand Metagenics
Barcode (UPC) 755571939180
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Mar 24, 2020
DSLD ID 216263
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for SpectraZyme Complete by Metagenics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
755571939180
IngredientAmount% DV
Amylase0 NP--
Lipase0 NP--
Lactase0 NP--
Cellulase0 NP--
Invertase0 NP--
Xylanase0 NP--
Pectinase0 NP--
Acid Protease0 NP--
Hemicellulase0 NP--
Protease, Fungal0 NP--
Neutral Protease0 NP--
Proprietary Complete Enzyme Blend271 mg--

Other ingredients: Capsule, Maltodextrin, Medium-Chain Triglycerides

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

SpectraZyme Complete provides digestive support with a non-GMO, broad spectrum of non-animal derived enzymes including acid stable lipase and three proteases that function in different pH ranges.

Formulation

This comprehensive enzyme complex is designed to support the healthy digestion of proteins, peptides, carbohydrates, fats, cellulose, maltose, lactose, and sucrose.

This product is non-GMO.

Broad spectrum digestive support

Suggested/Recommended/Usage/Directions

Directions: Take 2 capsules with each meal or as directed by your healthcare practitioner.

Precautions

Caution: If taking anti-diabetic medications, please consult your healthcare practitioner before use.

Contains: Milk, wheat, and soy.

Storage

Storage: Keep tightly closed in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

General Statements

Practitioner exclusive

See for yourself

SpectraZyme Complete by Metagenics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in SpectraZyme Complete by Metagenics

These are the 11 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Complete Enzyme Blend

271 mg per serving

Other (inactive) ingredients: Capsule, Maltodextrin, Medium-Chain Triglycerides. These complete the product’s ingredient list but are not active constituents.

Interaction report

SpectraZyme Complete by Metagenics Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in SpectraZyme Complete. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for SpectraZyme Complete, from the product label.

Metagenics

See all Metagenics products
Name
Metagenics
City
Gig Harbor
State
WA
ZipCode
98332
Phone Number
800 692 9400
Pharmacist Counseling Corner

SpectraZyme Complete by Metagenics: Common Questions

Does SpectraZyme Complete by Metagenics interact with any medications?
We do not currently list a known interaction for the mapped ingredients in SpectraZyme Complete. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
SpectraZyme Complete contains 11 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will SpectraZyme Complete help with lactose intolerance?
Lactase, one of the enzymes in this formula, is effective for lactose intolerance. It breaks down the milk sugar lactose, making dairy easier to digest if your body doesn't produce enough of its own lactase enzyme.
Is it safe to take SpectraZyme Complete while pregnant?
Safety data during pregnancy is limited for most of the enzymes in this formula. Lactase is likely safe, but the others—especially lipase and the proteases—haven't been well studied in pregnancy. Talk with your doctor before regular use.
Can I take SpectraZyme Complete if I'm breastfeeding?
Safety during breastfeeding hasn't been well studied for these enzymes. Check with your doctor or pharmacist first, since the data is too limited to know either way.
Does this product contain any fillers?
Yes—the inactive ingredients are a capsule, maltodextrin, and medium-chain triglycerides, which are used as filler and carrier materials to hold and deliver the active enzymes.
Are there any side effects I should watch for?
Most people tolerate it well. A small number may experience digestive upset or allergic reactions. Rarely, people with allergies to protease (particularly those with occupational exposure to protease powders) might have issues. If you have a serious digestive condition, use only under medical guidance.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if SpectraZyme Complete is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

SpectraZyme Complete label
Sources

Sources & How We Checked

SpectraZyme Complete's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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