SpectraZyme Complete Ingredients & Drug Interactions
by Metagenics
What is this page for?
First and foremost: checking SpectraZyme Complete against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
SpectraZyme Complete is a dietary supplement by Metagenics with 11 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of SpectraZyme Complete by Metagenics
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
SpectraZyme Complete contains 11 active digestive enzymes. Lactase helps break down milk sugar (lactose) — it's rated effective for lactose intolerance.
The other 10 enzymes work on different food components: lipase handles fats, amylase handles starches, proteases break down proteins, and the rest target various plant fibers and carbohydrates. The formula is rounded out with inactive ingredients: a capsule shell, maltodextrin, and medium-chain triglycerides.
Does it work?
Strong evidence
Lactase in this product is effective for lactose intolerance. The other enzymes — lipase, acid protease, and the rest — don't have strong evidence backing their use for any specific condition in the data we hold.
The effectiveness ratings for lipase show insufficient evidence for both dyspepsia (indigestion) and inflammatory bowel disease (IBD). No effectiveness data is on file for the proteolytic enzymes or the other carbohydrate-digesting enzymes.
How safe is it?
Well-documented data
Lactase is generally well tolerated and rated likely safe in pregnancy. The proteolytic enzymes (acid protease, fungal protease, and neutral protease) are generally well tolerated for most adults, but they may cause digestive upset or allergic reactions in some people.
These proteases should be avoided in pregnancy unless prescribed by a doctor, and there's little safety data during breastfeeding — check with your doctor first. Lipase is generally well tolerated in supplement form, though people with serious digestive conditions should use it only under medical supervision.
There's little safety data on supplemental lipase in pregnancy or while breastfeeding — use only if your doctor advises it. No adverse effects have been reported in adults with the other enzymes, though a thorough safety review hasn't been completed for all of them.
Meds to double-check
No known interactions
No interactions are documented in our data for the digestive enzymes in this product that we were able to check. Even so, if you take any prescription medications, it's smart to verify them with the interaction checker below — we could not check all ingredients in this blend.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
SpectraZyme Complete is a multi-enzyme digestive aid with lactase proven effective for lactose intolerance, though the other enzymes lack strong evidence for specific conditions. If you have serious digestive problems, are pregnant or breastfeeding, or take medications, check with your doctor or pharmacist first — especially before regular use in pregnancy.
No interactions are documented for the ingredients we checked, but run your medications through the tool on this page to be sure.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about SpectraZyme Complete, straight from the product label.
| Brand | Metagenics |
|---|---|
| Barcode (UPC) | 755571939180 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Mar 24, 2020 |
| DSLD ID | 216263 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for SpectraZyme Complete by Metagenics, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 0 NP | -- |
| Lipase | 0 NP | -- |
| Lactase | 0 NP | -- |
| Cellulase | 0 NP | -- |
| Invertase | 0 NP | -- |
| Xylanase | 0 NP | -- |
| Pectinase | 0 NP | -- |
| Acid Protease | 0 NP | -- |
| Hemicellulase | 0 NP | -- |
| Protease, Fungal | 0 NP | -- |
| Neutral Protease | 0 NP | -- |
| Proprietary Complete Enzyme Blend | 271 mg | -- |
Other ingredients: Capsule, Maltodextrin, Medium-Chain Triglycerides
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
SpectraZyme Complete provides digestive support with a non-GMO, broad spectrum of non-animal derived enzymes including acid stable lipase and three proteases that function in different pH ranges.
Formulation
This comprehensive enzyme complex is designed to support the healthy digestion of proteins, peptides, carbohydrates, fats, cellulose, maltose, lactose, and sucrose.
This product is non-GMO.
Broad spectrum digestive support
Suggested/Recommended/Usage/Directions
Directions: Take 2 capsules with each meal or as directed by your healthcare practitioner.
Precautions
Caution: If taking anti-diabetic medications, please consult your healthcare practitioner before use.
Contains: Milk, wheat, and soy.
Storage
Storage: Keep tightly closed in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
General Statements
Practitioner exclusive
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
SpectraZyme Complete by Metagenics label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in SpectraZyme Complete by Metagenics
These are the 11 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Complete Enzyme Blend
- › Amylase
- › Lipase
- › Lactase
- › Cellulase
- › Invertase
- › Xylanase
- › Pectinase
- › Acid Protease
- › Hemicellulase
- › Protease, Fungal
- › Neutral Protease
Other (inactive) ingredients: Capsule, Maltodextrin, Medium-Chain Triglycerides. These complete the product’s ingredient list but are not active constituents.
SpectraZyme Complete by Metagenics Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in SpectraZyme Complete. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for SpectraZyme Complete, from the product label.
Metagenics
See all Metagenics products- Name
- Metagenics
- City
- Gig Harbor
- State
- WA
- ZipCode
- 98332
- Phone Number
- 800 692 9400
SpectraZyme Complete by Metagenics: Common Questions
Does SpectraZyme Complete by Metagenics interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this help with bloating or gas?
Is it safe to take while pregnant?
Can I take this if I'm breastfeeding?
What is protease, and why is it in here?
Are there any fillers in this?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if SpectraZyme Complete is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind SpectraZyme Complete’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographLactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph → Herb & supplement monographProteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph →Sources & How We Checked
SpectraZyme Complete's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 5 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC