SPM Active Ingredients & Drug Interactions
by Metagenics
What is this page for?
First and foremost: checking SPM Active against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
SPM Active is a dietary supplement by Metagenics with 3 active ingredients.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of SPM Active by Metagenics
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
None of the active ingredients could be matched to our evidence database, so intended use can't be graded.
Why this rating?
- None of the active ingredients could be matched to a HelloPharmacist monograph, so intended use can't be graded against our evidence data.
Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.
Why this rating?
- The label discloses an exact amount for 0 of its 3 active ingredients.
- “Active Fractionated Marine Lipid Concentrate” is listed as a grouped ingredient — the label gives one combined amount (1 Gram(s)) without saying how much of each component you get.
None of the active ingredients could be matched to our interaction database.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was nothing to check interactions against.
None of the active ingredients could be matched to our safety data.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was no safety data to measure.
HelloPharmacist summaryFormula with limited ingredient disclosure with no assessable stated purpose. Medication interactions could not be assessed, and safety information could not be assessed.
Assessment coverage: 0 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about SPM Active, straight from the product label.
| Brand | Metagenics |
|---|---|
| Barcode (UPC) | 755571952295 |
| Net contents | 60 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Aug 23, 2023 |
| DSLD ID | 295865 |
| Product type | Fat/fatty Acid |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for SPM Active by Metagenics, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 10 Calorie(s) | -- |
| Cholesterol | 5 mg | 2% |
| Total Fat | 1 Gram(s) | 1% |
| 18-Hydroxyeicosapentaenoic Acid | 0 NP | -- |
| 14-Hydroxydocosahexaenoic acid | 0 NP | -- |
| 17-Hydroxydocosahexaenoic Acid | 0 NP | -- |
| Active Fractionated Marine Lipid Concentrate | 1 Gram(s) | -- |
Other ingredients: Fish Oil, Mixed Tocopherols, Gelatin, Glycerin, Water, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
SPM Active is designed to help support the body's natural capacity to respond to physical challenges and resolve the immune response.
This product is non-GMO and gluten-free.
Specialized pro-resolving mediators
Suggested/Recommended/Usage/Directions
Directions: take two softgels once daily or as directed by your healthcare practitioner.
Precautions
Caution: if pregnant, nursing, or taking nutritional supplements or medications, consult your healthcare practitioner before use.
Keep out of the reach of children.
Tamper evident: Do not use if safety seal is missing or broken.
Practitioner exclusive
Contains: Fish (anchovy, sardine, and mackerel).
Storage
Storage: Keep tightly closed in a cool, dry place.
Brand IP Statement(s)
Lipinova is a registered trademark of Solutex Lipinova Specialized pro-resolving lipid mediators
US patents 11,077,083 and 11,077,084
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
SPM Active by Metagenics label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in SPM Active by Metagenics
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Active Fractionated Marine Lipid Concentrate
- › 18-Hydroxyeicosapentaenoic Acid
- › 14-Hydroxydocosahexaenoic acid
- › 17-Hydroxydocosahexaenoic Acid
Other (inactive) ingredients: Fish Oil, Mixed Tocopherols, Gelatin, Glycerin, Water, Silica. These complete the product’s ingredient list but are not active constituents.
SPM Active by Metagenics Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in SPM Active. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for SPM Active, from the product label.
Metagenics
See all Metagenics products- Name
- Metagenics
- City
- Gig Harbor
- State
- WA
- ZipCode
- 98332
- Phone Number
- 800 692 9400
SPM Active by Metagenics: Common Questions
Does SPM Active by Metagenics interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if SPM Active is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
Sources & How We Checked
SPM Active's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC