No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Star Anise Extract Ingredients & Drug Interactions

by BulkSupplements.com

Star Anise Extract label
See full label image
Powder Category: Botanical
No known interaction
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Star Anise Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Star Anise Extract is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for digestive upset and gas, cough and respiratory complaints, antimicrobial.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

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HelloPharmacist Scorecard of Star Anise Extract by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: star anise extract, a concentrated form of the culinary spice. Star anise is the dried fruit of a star-shaped plant native to southeast Asia, traditionally used in cooking and herbal preparations.

The product contains no other inactive ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Star Anise product and its label doesn't state a use — see Star Anise's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We hold no effectiveness data for star anise extract in our records. The evidence for what this ingredient does is not established in the information we have on file.

The evidence, ingredient by ingredient Star Anise

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Star anise is generally well tolerated in the small amounts you'd use in food — a pinch in your tea or soup is fine. But this product is a concentrated supplement, and the safety data for that form isn't established.

The main caution: star anise tea has been tied to serious neurological effects in rare cases, including seizures, rapid eye movements, irritability, and vomiting. It's unclear whether these were caused by contamination with a toxic look-alike species or by star anise itself.

Applied to skin, star anise can cause dermatitis (redness, scaling, blistering). The safety data also flags contamination risk in supplement and tea forms, so concentrated powders warrant extra care.

Side effects, ingredient by ingredient Star Anise

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the star anise extract we could check. That said, because serious neurological effects have been reported (albeit rarely) with star anise tea, anyone taking seizure medications, central nervous system depressants, or psychiatric medications should discuss this product with their own doctor or pharmacist before starting it.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

If you use star anise in cooking, you're fine — food amounts are generally safe. For this concentrated supplement form, safety hasn't been well established, and there's a documented risk of contamination and rare serious neurological effects.

Talk it over with your doctor or pharmacist before you start, especially if you have a seizure disorder or take nervous system medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Star Anise Extract, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X000Z78P3X
Net contents 1 kg; 35.3 Oz(s)
Market status On market
Date entered into DSLD Aug 23, 2021
DSLD ID 252910
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Star Anise Extract by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
500 mg
Maximum serving Sizes:
500 mg
Servings per container
2000
UPC/BARCODE
X000Z78P3X
IngredientAmount% DV
Star Anise extract500 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Clean & pure bulk supplements

New – Bulksupplements Star Anise Powder (1 kilogram)

Formulation

Color may vary

Free of: added sugar, soy, dairy, yeast, gluten, additives

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 500 mg (about 1/5 tsp) one to three times daily, or as directed by a physician.

Storage

Store in a dry, cool place

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Star Anise Extract by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Star Anise Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Star Anise Extract by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size500 mg Dosage formPowder Servings per container2000 Amounts shown are per serving.

Star Anise extract

No known
interactions
500 mg per serving

Star anise (Illicium verum) is a star-shaped spice widely used in cooking and traditional medicine, mostly for digestive and respiratory complaints. H...

Star Anise extract monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Star Anise Extract by BulkSupplements.com Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Star Anise Extract. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Star Anise Extract, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

Star Anise Extract by BulkSupplements.com: Common Questions

Does Star Anise Extract by BulkSupplements.com interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Star Anise Extract. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Star Anise Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is star anise extract safe to take every day?
Safety data for the concentrated supplement form isn't established. The culinary spice in food amounts is generally well tolerated, but this product is much more concentrated. We also can't rule out contamination risk. Talk with your doctor or pharmacist about whether daily use is right for you.
Can I take this if I'm pregnant or breastfeeding?
The data shows conflicting ratings — one source says it's likely safe, another says possibly unsafe. That's not clear enough to go on alone. Work with your doctor or midwife to decide what's best for you and your baby.
What are the side effects of star anise extract?
In food amounts, it's generally well tolerated with no common side effects. But star anise tea has been linked to serious nervous system effects in rare cases — seizures, rapid eye movements, jitteriness, and vomiting — though contamination may play a role. Applied to skin, it can cause redness, scaling, and blistering.
Is there a risk of contamination in this powder?
Yes — the data flags contamination risk as a concern with star anise supplements and teas, particularly from a toxic look-alike species. That's one reason the safety of the concentrated supplement form isn't well established.
Why does the product label mention Japanese star anise?
Japanese star anise (Illicium apisatum) is a toxic look-alike. Some of the serious neurological effects reported with star anise tea may have come from contamination with this poisonous species mixed in during processing or harvesting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Star Anise Extract is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Star Anise Extract label
Go deeper

The Full Monographs Behind Star Anise Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Star Anise

Star anise (Illicium verum) is a star-shaped spice widely used in cooking and traditional medicine, mostly for digestive and respiratory complaints. Human evidence for health benefits is lim...

Read the full Star Anise monograph →
Sources

Sources & How We Checked

Star Anise Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Star Anise 10 references
  1. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  2. Anon. FDA issue advisory on star anise "teas." FDA News P03-67; September 10, 2003.
  3. Ize-Ludlow D, Ragone S, Bernstein JN, et al. Chemical composition of Chinese star anise (Illicium verum) and neurotoxicity in infants. JAMA 2004;291:562-3. PubMed
  4. Ize-Ludlow D, Ragone S, Bruck IS, et al. Neurotoxicities in infants seen with the consumption of star anise tea. Pediatrics 2004;114:e653-6. PubMed
  5. Franks A. Contact allergy to anethole in toothpaste associated with loss of taste. Contact Dermatitis 1998;38:354-5. PubMed
  6. Rudzki E, Grzywa Z. Sensitizing and irritating properties of star anise oil. Contact Dermatitis 1976;2:305-8. PubMed
  7. Garzo, Fernandez C., Gomez, Pintado P., Barrasa, Blanco A., Martinez, Arrieta R., Ramirez, Fernandez R., and Ramon, Rosa F. [Cases of neurological symptoms associated with star anise consumption used as a carminative]. An.Esp.Pediatr. 2002;57(4):290-294.
  8. Minodier, P., Pommier, P., Moulene, E., Retornaz, K., Prost, N., and Deharo, L. [Star anise poisoning in infants]. Arch Pediatr. 2003;10(7):619-621.
  9. Casanova Cuenca M, Calzado Agrasot MÁ, Mir Pegueroles C, Esteban Cantó V. New cases of star anise poisoning: Are we providing enough information? Neurologia. 2019;34(3):211-213. DOI
  10. Donner J, Ruest S. Neonate with seizures after consuming star anise tea. R I Med J. 2021 Oct 1;104(8):8-10.

See these in context on the Star Anise monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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