No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Sulbutiamine 500 mg Ingredients & Drug Interactions

by Absorb Health

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Sulbutiamine 500 mg is a dietary supplement by Absorb Health with 1 active ingredient. Its ingredients are commonly taken for fatigue and low energy, memory and focus, mental clarity.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Sulbutiamine 500 mg by Absorb Health

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: sulbutiamine, a fat-soluble form of thiamine (vitamin B1). The capsule also holds gelatin, maltodextrin, and silica as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Sulbutiamine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: cognitive support and energy.
  • We looked for evidence on: Fatigue, Multiple sclerosis-related fatigue, mental clarity, focus.
  • The closest evidence on file: Sulbutiamine is rated "Insufficient Reliable Evidence To Rate" for Multiple sclerosis-related fatigue (Natural Medicines).

The evidence for sulbutiamine isn't established in the data we hold. It's been studied for diabetic neuropathy (nerve damage from diabetes), fatigue, and multiple sclerosis-related fatigue, but the available research isn't strong enough to rate it effective for any of these uses.

The evidence, ingredient by ingredient Sulbutiamine

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 0 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sulbutiamine is generally well tolerated in the short term — the longest study we have data for ran 4 weeks. Long-term safety hasn't been well studied, so caution is warranted if you're thinking about taking it for months on end.

The safety data advises against use during pregnancy and while breastfeeding.

Side effects, ingredient by ingredient Sulbutiamine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for sulbutiamine in our data. That said, because long-term safety information is limited, it's still worth mentioning this product to your pharmacist when you pick up or refill any prescription medications.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and some safety-information gaps remain.

If you're considering sulbutiamine for fatigue or nerve pain, know that the evidence supporting it is weak. It appears tolerable short-term, but we don't know much about long-term use.

Talk with your pharmacist or doctor about whether it makes sense for you, especially if you're pregnant, breastfeeding, or taking other medications regularly.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sulbutiamine 500 mg, straight from the product label.

Brand Absorb Health
Barcode (UPC) 025706834599
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Mar 24, 2020
DSLD ID 215918
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sulbutiamine 500 mg by Absorb Health, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
100 Capsule(s)
Maximum serving Sizes:
100 Capsule(s)
Servings per container
100
UPC/BARCODE
025706834599
IngredientAmount% DV
Sulbutiamine500 mg--

Other ingredients: Gelatin, Maltodextrin, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of the reach of children.

Do not use if seal under cap is broken or missing.

Storage

Store at room temperature with lid tightly closed.

Formulation

Cognitive Support

No cutting agents

General Statements

Shop at www.absorbyourhealth.com for all your mind, body, and spirit needs.

See for yourself

Sulbutiamine 500 mg by Absorb Health label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Sulbutiamine 500 mg by Absorb Health

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size100 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Sulbutiamine

No known
interactions
500 mg per serving

Sulbutiamine is a man-made, fat-soluble form of vitamin B1 (thiamine) developed in Japan, often taken for fatigue and to support mental energy and foc...

Sulbutiamine monograph & interactions

Other (inactive) ingredients: Gelatin, Maltodextrin, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sulbutiamine 500 mg by Absorb Health Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Sulbutiamine 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Sulbutiamine 500 mg, from the product label.

Absorb Health

See all Absorb Health products
Name
Absorb Health
Web Address
www.absorbyourhealth.com
Pharmacist Counseling Corner

Sulbutiamine 500 mg by Absorb Health: Common Questions

Does Sulbutiamine 500 mg by Absorb Health interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Sulbutiamine 500 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Sulbutiamine 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is sulbutiamine safe to take long-term?
We don't have enough data to say. The longest study on file lasted 4 weeks. If you're thinking about taking it for months, run it by your pharmacist so they can watch for anything unexpected.
Can I take sulbutiamine while pregnant?
The safety data advises against it — there isn't enough information to know it's safe. Talk with your doctor or pharmacist about what makes sense for you.
Can I take sulbutiamine while breastfeeding?
The safety data advises against it. There's not enough information to know whether it's safe for your baby. Discuss options with your doctor or pharmacist.
What side effects might I notice?
In clinical studies, headache, insomnia, tremor, drowsiness, and nausea were each reported in very small numbers of people. Most users tolerated it without reported problems.
Does sulbutiamine actually work for fatigue?
The evidence isn't strong enough to say it does. It's been studied for fatigue and multiple sclerosis-related fatigue, but the research doesn't support a clear benefit yet.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Sulbutiamine 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sulbutiamine 500 mg label
Go deeper

The Full Monographs Behind Sulbutiamine 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Sulbutiamine 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sulbutiamine 4 references
  1. Shah S. Adjuvant role of vitamin B analogue (sulbutiamine) with anti-infective treatment in infection associated asthenia. J Assoc Physicians India. 2003;51:891-5.
  2. Loo H, Poirier M, Ollat H, et al. [Effects of subutiamine (Arcalion 200) on psycho-behavioral inhibition in major depressive episodes]. Encephale. 2000;26(2):70-5.
  3. Kiew K, Wan Mohamad W, Ridzuan A, et al. Effects of sulbutiamine on diabetic polyneuropathy: an open randomized controlled study in type 2 diabetics. Malays J Med Sci. 2002;9(1):21-7.
  4. Sevim S, Kaleagasi H, Tasdelen B. Sulbutiamine shows promising results in reducing fatigue in patients with multiple sclerosis. Mult Scler Relat Disord. 2017;16:40-43. PubMed

See these in context on the Sulbutiamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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