Sulbutiamine Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Sulbutiamine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Sulbutiamine is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for fatigue and low energy, memory and focus, mental clarity.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Sulbutiamine by BulkSupplements.com
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: sulbutiamine, a form of thiamine (vitamin B1). It's used in some countries to address fatigue and nerve-related discomfort, though the evidence supporting those uses remains limited.
Does it work?
Not established
The evidence for sulbutiamine isn't established in our data. We have insufficient reliable evidence to rate it for diabetic neuropathy, general fatigue, or fatigue related to multiple sclerosis.
If you're considering it for any of those reasons, talk with your doctor or pharmacist about what the research actually shows and whether it's a fit for your situation.
How safe is it?
Some data gaps
Sulbutiamine is generally well tolerated in the short term — it's been used safely at 600 mg daily for up to 4 weeks in limited studies. Long-term safety isn't well established, though.
In trial reports, a small number of patients reported headache, insomnia, tremor, drowsiness, and nausea, each in fewer than one in a thousand users. Because there isn't enough safety data, we advise against using this supplement during pregnancy or while breastfeeding — talk with your doctor if you're pregnant, planning to become pregnant, or nursing.
Meds to double-check
No known interactions
No interactions are documented in our data for sulbutiamine. That said, absence of documented interactions isn't a guarantee none exist, so run your exact medications through the checker on this page before you start.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and some safety-information gaps remain.
Sulbutiamine may be worth exploring if your doctor or pharmacist thinks it fits your needs, and short-term use appears tolerated in the limited research we have. Don't use it in pregnancy or while breastfeeding.
Since long-term safety data is thin, this is a good one to discuss with your pharmacist before starting, especially if you plan to use it for weeks or months.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Sulbutiamine, straight from the product label.
| Brand | BulkSupplements.com |
|---|---|
| Net contents | 250 Gram(s); 8.82 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Oct 22, 2021 |
| DSLD ID | 254575 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Sulbutiamine by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Clean & pure bulk supplements
Precautions
Warning: Do not take this supplement if you have high blood pressure or are under 18 years of age.
This product is not intended for use by those with a serious medical condition or pregnant or lactating women.
Consult your physician before use.
Warning: Do not take this supplement if you have high blood pressure or are under 18 years of age.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formulation
Free of: Sugar, soy, dairy, yeast, gluten or additives
Suggested/Recommended/Usage/Directions
Directions: Take 200 milligrams once or twice daily, or as directed by a physician. Since the body forms a tolerance to this product, individual needs will vary. Use an accurate milligram scale to measure.
Storage
Storage: Keep dry, cool & dark
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Sulbutiamine by BulkSupplements.com label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Sulbutiamine by BulkSupplements.com
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size200 mg Dosage formPowder Servings per container1250 Amounts shown are per serving.
Sulbutiamine
No knowninteractions
Sulbutiamine is a man-made, fat-soluble form of vitamin B1 (thiamine) developed in Japan, often taken for fatigue and to support mental energy and foc...
Sulbutiamine monograph & interactionsOther (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.
Sulbutiamine by BulkSupplements.com Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Sulbutiamine. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Sulbutiamine, from the product label.
BulkSupplements.com
See all BulkSupplements.com products- Name
- BulkSupplements.com
- Street Address
- 7511 Eastgate Road
- City
- Henderson
- State
- NV
- ZipCode
- 89011
- Web Address
- BulkSupplements.com
Sulbutiamine by BulkSupplements.com: Common Questions
Does Sulbutiamine by BulkSupplements.com interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take sulbutiamine if I'm pregnant or breastfeeding?
What side effects did people report in studies?
How long can I safely take sulbutiamine?
Does sulbutiamine actually work for fatigue?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Sulbutiamine is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Sulbutiamine’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Sulbutiamine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sulbutiamine 4 references
- Shah S. Adjuvant role of vitamin B analogue (sulbutiamine) with anti-infective treatment in infection associated asthenia. J Assoc Physicians India. 2003;51:891-5.
- Loo H, Poirier M, Ollat H, et al. [Effects of subutiamine (Arcalion 200) on psycho-behavioral inhibition in major depressive episodes]. Encephale. 2000;26(2):70-5.
- Kiew K, Wan Mohamad W, Ridzuan A, et al. Effects of sulbutiamine on diabetic polyneuropathy: an open randomized controlled study in type 2 diabetics. Malays J Med Sci. 2002;9(1):21-7.
- Sevim S, Kaleagasi H, Tasdelen B. Sulbutiamine shows promising results in reducing fatigue in patients with multiple sclerosis. Mult Scler Relat Disord. 2017;16:40-43. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC