No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Super Collagen Matrix (Type II) Ingredients & Drug Interactions

by R & D Pharmaceutical

Capsule Category: Other Combinations
No known interaction
The interaction bottom line No known interaction

Super Collagen Matrix (Type II) is a dietary supplement by R & D Pharmaceutical with 1 active ingredient. Its ingredients are commonly taken for skin health and wrinkles, joint pain and osteoarthritis, bone health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Super Collagen Matrix (Type II) by R & D Pharmaceutical

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Hydrolyzed Type II Collagen” is listed as a grouped ingredient — the label gives one combined amount (1,000 mg) without saying how much of each component you get.

This product contains 1 active ingredient: hyaluronic acid, a substance your body naturally produces that helps retain moisture in skin and connective tissue. The hydrolyzed Type II collagen is listed as a blend, meaning its component ingredients are broken down separately in the supplement.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Hyaluronic Acid's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: maintain healthy cartilage, joints, skin.
  • We looked for evidence on: Aging skin, Brittle nails, Cellulite, Dry skin, Exercise-induced muscle soreness, Joint pain — and 4 related terms.
  • The closest evidence on file: Hyaluronic Acid is rated "Insufficient Reliable Evidence To Rate" for Aging skin (Natural Medicines).
  • Also on file: Hyaluronic Acid is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle soreness, Osteoarthritis.

Hyaluronic acid is possibly effective for dry eye and venous leg ulcers (slow-healing wounds in the lower leg). For aging skin, hay fever, and sexual dysfunction, there isn't enough reliable evidence yet to rate whether it works.

The data we hold doesn't establish effectiveness for other uses.

The evidence, ingredient by ingredient Collagen Peptides Hyaluronic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hyaluronic acid is generally well tolerated when taken by mouth or applied to skin. The most common side effects from topical use are eczema, redness, itching, and in rare cases, wound bleeding or infection.

Eye drops containing hyaluronic acid have rarely caused eye pain. The long-term safety of oral supplements isn't fully studied, so talk with your doctor before starting if you have ongoing health concerns.

Side effects, ingredient by ingredient Collagen Peptides Hyaluronic Acid

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for the ingredients we could check. You're clear to use this alongside your medications, but run your exact drug list through the interaction checker on this page just to be sure.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

If you're considering this for dry eye or slow-healing leg wounds, hyaluronic acid has some evidence behind it. For skin aging or allergies, the evidence isn't clear yet.

Since long-term safety data is limited, it's worth a quick conversation with your pharmacist or doctor first, especially if you take any medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Super Collagen Matrix (Type II), straight from the product label.

Brand R & D Pharmaceutical
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Oct 25, 2018
DSLD ID 182528
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Super Collagen Matrix (Type II) by R & D Pharmaceutical, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
IngredientAmount% DV
Hydrolyzed Type II Collagen1000 mg--
Hyaluronic Acid100 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Super Collagen Matrix (Type II) contains the only purified & natural form of active HA Type II collagen with low molecular weight for easy absorption through our intestinal tract.

Brand IP Statement(s)

It was treated through a Japan Patented (2971860) enzymatically splitting process to produce into small & low molecules of HA in Type II Collagen.

Japan Patent Approved 2971860

General Statements

Super Collagen Matrix (Type II) helps maintain healthy cartilages, joints, connective tissues & youthful skin.

For joints & skin

Super Collagen Matrix (Type II) may have the following benefits: Acts like a shock absorber for joints Lubricates joints for mobility & flexibility Maintains healthy synovial fluids Assists natural healing of soft tissues Important nutrient for skin & eyes

Manufactured to USP (United States Pharmacopoeia) and GMP (Good Manufacturing Practices) standards.

Suggested/Recommended/Usage/Directions

Dosage: Take 1 capsule twice daily before meals or subjected to your physician's prescription

Storage

Storage: Store in a cool & dry place

Precautions

Keep out of reach of children

FDA Statement of Identity

Pharmaceutical Grade Dietary Supplement

Formulation

This product does not contain artificial preservatives, artificial sweeteners, colors, flavors & sugar.

See for yourself

Super Collagen Matrix (Type II) by R & D Pharmaceutical label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Super Collagen Matrix (Type II) by R & D Pharmaceutical

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Hydrolyzed Type II Collagen

No known
interactions
1000 mg per serving

Collagen peptides are a well-absorbed form of protein that may modestly improve skin elasticity and joint comfort for some people, though evidence is...

Hydrolyzed Type II Collagen monograph & interactions
Interaction report

Super Collagen Matrix (Type II) by R & D Pharmaceutical Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Super Collagen Matrix (Type II). This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Super Collagen Matrix (Type II), from the product label.

R & D Pharmaceutical

See all R & D Pharmaceutical products
Name
R & D Pharmaceutical Pte Ltd
Phone Number
65-6100 1368
Pharmacist Counseling Corner

Super Collagen Matrix (Type II) by R & D Pharmaceutical: Common Questions

Does Super Collagen Matrix (Type II) by R & D Pharmaceutical interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Super Collagen Matrix (Type II). This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Super Collagen Matrix (Type II) contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does hyaluronic acid really help with dry eyes?
It's possibly effective for dry eye, meaning there's some evidence it can help, but it's not a guaranteed fix. If you're dealing with dry eyes, ask your pharmacist whether it's a good fit for you.
What side effects might I notice?
Most people tolerate it well. Topical (skin-applied) forms can occasionally cause redness, itching, or eczema. Eye drops are generally safe too, though eye pain has been reported rarely. If you notice any irritation, stop and tell your pharmacist.
Is this safe to take long-term?
Hyaluronic acid appears well tolerated, but long-term safety of oral supplements hasn't been fully studied yet. It's worth checking in with your doctor if you're planning to take it for months on end.
Will this help my skin look younger?
There isn't enough reliable evidence to say whether hyaluronic acid works for aging skin. It's one people try, but we can't promise results based on the data we have.
Can I take this while pregnant or breastfeeding?
There's no safety data on file for hyaluronic acid in pregnancy or breastfeeding. Talk with your doctor or midwife before starting—they can give you personalized advice based on your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Super Collagen Matrix (Type II) is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Super Collagen Matrix (Type II) label
Sources

Sources & How We Checked

Super Collagen Matrix (Type II)'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Collagen Peptides 2 references
  1. Trc T, Bohmová J. Efficacy and tolerance of enzymatic hydrolysed collagen (EHC) vs. glucosamine sulphate (GS) in the treatment of knee osteoarthritis (KOA). Int Orthop. 2011;35(3):341-8. PubMed
  2. Evans M, Lewis ED, Zakaria N, Pelipyagina T, Guthrie N. A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. J Cosmet Dermatol. 2021;20(3):825-834. PubMed

See these in context on the Collagen Peptides monograph →

Hyaluronic Acid 4 references
  1. Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
  2. U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
  3. Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
  4. Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed

See these in context on the Hyaluronic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring