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Dietary supplement

Horseradish Ingredients & Drug Interactions

by R & D Pharmaceutical

Horseradish label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Horseradish against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Horseradish is a dietary supplement by R & D Pharmaceutical with 1 active ingredient. Its ingredients are commonly taken for sinus and respiratory congestion, urinary tract infections, digestive support.Based on those ingredients, 16 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Armoracia rusticana root concentrate extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Horseradish by R & D Pharmaceutical

Ask about any prescription or over-the-counter medication and we check it for interactions with Horseradish by R & D Pharmaceutical — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Horseradish by R & D Pharmaceutical

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Armoracia rusticana root concentrate extract—a concentrated form of horseradish root. The capsule itself has no other inactive ingredients listed.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: respiratory health and urinary tract support.
  • We looked for evidence on: Respiratory tract infections, Urinary tract infections (UTIs), Sinus congestion, Immune function.
  • The closest evidence on file: Horseradish is rated "Insufficient Reliable Evidence To Rate" for Respiratory tract infections (Natural Medicines).
  • Also on file: Horseradish is rated "Insufficient Reliable Evidence To Rate" for Urinary tract infections (UTIs).

The evidence for horseradish isn't established yet in the data we hold. The product is marketed for respiratory tract infections, urinary tract infections, intestinal parasites, and gout, but reliable evidence to support these uses is insufficient.

More research is needed to know whether it actually works for these conditions.

The evidence, ingredient by ingredient Horseradish

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Horseradish in food amounts is generally well tolerated. But concentrated supplements can irritate your digestive tract and mucous membranes.

Large amounts may cause gastrointestinal upset, bloody vomiting, diarrhea, or mouth and throat irritation. In rare cases, very large amounts have been linked to a sudden drop in blood pressure and fainting (vasovagal syncope).

During pregnancy, avoid medicinal amounts because safety hasn't been established. For breastfeeding, the data is conflicting—one source says likely safe, another says likely unsafe—so there isn't enough clarity.

Talk with your doctor or pharmacist about whether it's right for you during lactation.

Side effects, ingredient by ingredient Horseradish

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Horseradish.
  • The most serious interaction on file is rated Moderate.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist if you take thyroid hormones (Moderate interaction). The horseradish extract may interfere with how well your thyroid medication works.

Use the checker below to verify your exact medications before you start.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Horseradish may help with infections or gout, but the evidence isn't solid yet. The main caution is its potential to interfere with thyroid medications.

If you take thyroid drugs, check with your doctor or pharmacist before starting. Stick to food amounts rather than concentrated supplements to avoid digestive upset.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Horseradish, straight from the product label.

Brand R & D Pharmaceutical
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Oct 25, 2018
DSLD ID 182523
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Horseradish by R & D Pharmaceutical, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
IngredientAmount% DV
Armoracia rusticana root concentrate extract600 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Indication Anti oxidant & maintains healthy immune system.

Manufactured to USP and GMP standards

Suggested/Recommended/Usage/Directions

Direction Take 1 capsule two times daily after meals or subjected to physician's prescription

Storage

Storage Keep refrigerated or store in a cool & dry place

Precautions

Keep out of reach of children

FDA Statement of Identity

Pharmaceutical Grade Dietary Supplement

Formula

Horseradish root may have the following benefits: It may Help clears phlegm and relax airways in respiratory tract infection; Help strengthens our immunity against bacterial or viral infections; Help maintains healthy urinary tract system.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Horseradish by R & D Pharmaceutical label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Horseradish label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Horseradish by R & D Pharmaceutical

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Armoracia rusticana root concentrate extract

Interacts with
16 drugs
600 mg per serving

Horseradish is a pungent root used as a food and folk remedy, most often for sinus congestion and urinary tract complaints. Human evidence is limited,...

Armoracia rusticana root concentrate extract monograph & interactions
Interaction report

Horseradish by R & D Pharmaceutical Drug Interactions

Want to check YOUR meds against Horseradish?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
16Drugs
16 Moderate

Ingredients driving the most interactions

Armoracia rusticana root concentrate extract 16

Individual Drug Interactions

The ingredients in Horseradish interact with 16 drugs. Click any drug to see the details.

1 of the 1 ingredient in Horseradish interact with drugs. Each result below shows which ingredient is responsible. Armoracia rusticana root concentrate extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Horseradish with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Armoracia rusticana root concentrate extract1 drug type · 16 drugs

Thyroid Hormone

Theoretically, horseradish might interfere with the effects of thyroid hormone.
Horseradish and other members of the cabbage and mustard family are associated with depressed thyroid function.

Likelihood Possible Evidence D
Armoracia rusticana root concentrate extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Horseradish, from the product label.

R & D Pharmaceutical

See all R & D Pharmaceutical products
Name
R & D Pharmaceutical Pte Ltd
Phone Number
65-6100 1368
Pharmacist Counseling Corner

Horseradish by R & D Pharmaceutical: Common Questions

Does Horseradish by R & D Pharmaceutical interact with any medications?
Yes. Based on its ingredients, Horseradish has a known interaction with 16 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Horseradish contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on thyroid medication?
Horseradish may interfere with how your thyroid drugs work because it can suppress thyroid function. Talk with your doctor or pharmacist before combining them—don't start without checking first.
What are the main side effects I should watch for?
At food amounts, it's usually fine. But large doses can cause stomach upset, diarrhea, bloody vomit, and irritation of your mouth and throat. Very rarely, large amounts have caused fainting due to a sudden blood pressure drop.
Is it safe to take while breastfeeding?
The safety data we have is unclear—some sources say likely safe in food amounts, others flag medicinal use as unsafe. Talk with your doctor or pharmacist for personalized advice.
Does this actually work for UTIs or respiratory infections?
The evidence isn't established yet. While horseradish is used for these conditions, we don't have reliable data showing it actually works. More research is needed.
What's the difference between food amounts and a supplement?
A horseradish capsule is a concentrated extract, much stronger than the small amounts you'd get on your plate with dinner. The concentrated form is more likely to cause digestive upset and interact with medications.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Horseradish is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Horseradish label
Go deeper

The Full Monographs Behind Horseradish’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Horseradish

Interacts with 16 drugs

Horseradish is a pungent root used as a food and folk remedy, most often for sinus congestion and urinary tract complaints. Human evidence is limited, and while culinary amounts are generall...

Read the full Horseradish monograph →
Sources

Sources & How We Checked

Horseradish's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Horseradish 6 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  4. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  5. Panter, K. E. and James, L. F. Natural plant toxicants in milk: a review. J Anim Sci 1990;68(3):892-904. PubMed
  6. Lehmann CU, Puckett AL, Betz BO. 56-year-old man - increased heart rate - weakness - intense sweating - horseradish consumption - Dx?. J Fam Pract 2022;71(7):317-321. PubMed

See these in context on the Horseradish monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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