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Dietary supplement

Super Strength Bilberry 6000 mg Ingredients & Drug Interactions

by Simply Supplements

Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Super Strength Bilberry 6000 mg is a dietary supplement by Simply Supplements with 1 active ingredient. Its ingredients are commonly taken for eye and vision health, antioxidant support, diarrhea and digestive upset.Based on those ingredients, 275 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bilberry extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Super Strength Bilberry 6000 mg by Simply Supplements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: bilberry extract at a 6000 mg dose per tablet. Bilberry is a berry related to the blueberry, and the extract concentrates its active compounds — mainly anthocyanidins, which are plant pigments with antioxidant properties.

The tablet also contains inactive ingredients (microcrystalline cellulose, dicalcium phosphate, magnesium stearate, and silica) that serve as binders and fillers.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: eye and vision health support.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Diabetic retinopathy, Dry eye, Glaucoma — and 4 related terms.
  • The closest evidence on file: Bilberry is rated "Possibly Ineffective" for Night vision (Natural Medicines).
  • Also on file: Bilberry is rated "Insufficient Reliable Evidence To Rate" for Age-related macular degeneration (AMD), Cataracts, Diabetic retinopathy, Dry eye, and more.

The evidence for bilberry's effectiveness is mixed and limited. Night vision is rated Possibly Ineffective — so this supplement likely won't sharpen your sight in dim light.

For age-related macular degeneration, age-related cognitive decline, atherosclerosis, high cholesterol, and chronic venous insufficiency, we don't have enough reliable evidence to say whether it works or doesn't. If any of these are reasons you're considering bilberry, it's worth talking through the evidence with your pharmacist or doctor first.

The evidence, ingredient by ingredient Bilberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bilberry extract is generally well tolerated when taken by mouth. The most common side effects are minor gastrointestinal ones — dark stools, gas, and mild stomach discomfort.

Some people also noticed their stools, tongue, or teeth became dark blue or black, which is harmless but can be surprising. That said, long-term safety data for bilberry supplements is limited.

While eating bilberries as food is fine, the safety notes advise against taking concentrated supplement doses because we simply don't have enough long-term safety information. Bilberry is rated Likely Safe in pregnancy and lactation, so that's one less concern if you're in either situation.

Side effects, ingredient by ingredient Bilberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bilberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 275 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this bilberry supplement, double-check it with your pharmacist if you're on blood thinners or antiplatelet drugs (like warfarin, aspirin, or clopidogrel) — Moderate risk of increased bleeding. Also flag it if you take diabetes medications, erlotinib for cancer, or any drugs your body processes through the CYP2E1 enzyme.

The interaction checker below will help you confirm your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Bilberry might appeal to you if you're after general antioxidant support, but evidence that it actually works for its marketed uses is weak or absent. If you take blood thinners, diabetes drugs, or erlotinib, you need to check with your pharmacist first — this supplement can interfere.

The main side effects are digestive and harmless discoloration of your stool or tongue. Talk to your pharmacist about whether this product makes sense for you and your medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 24, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Super Strength Bilberry 6000 mg, straight from the product label.

Brand Simply Supplements
Barcode (UPC) 5060370562671
Net contents 180 Tablet(s)
Market status On market
Date entered into DSLD Feb 24, 2017
DSLD ID 70582
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Super Strength Bilberry 6000 mg by Simply Supplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
UPC/BARCODE
5060370562671
IngredientAmount% DV
Bilberry extract600 mg--

Other ingredients: Microcrystalline Cellulose, Dicalcium Phosphate, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Each tablet contains:

Product information Bilberries naturally contain a plant-pigment flavonoid called Anthocyanandin, alongside vitamins A and C.

Do not exceed stated dose.

Image is for illustration purposes only.

AutoDespatch Save 10% and get free P&P on all repeat orders by having your favourite supplements conveniently scheduled and delivered automatically with our unique AutoDespatch system. Same day Despatch We will ensure your order is despatched on the day of receipt (when placed before 12.30pm) and that all orders placed after 12.30pm are despatched on the next working day. All sent 1st class!

PriceMatch guarantee! If you buy from us and then see the same product cheaper elsewhere we will refund the difference plus 10%!

Formula

Natural source of flavonoids

Seals/Symbols

Quality assured

V Vegetarian

Suggested/Recommended/Usage/Directions

Suggested daily intake Take two tablets daily as a food supplement or as directed by a healthcare professional.

Precautions

Important information If you are taking any prescription medication, you have a medical condition or you have specific concerns about the suitability of our products, always consult your GP or Pharmacist prior to taking supplements.

Keep away from children at all times.

Do not use if seal is broken.

Pregnant or lactating women should consult a Doctor before using this product.

Food supplement: This product should not be used as a substitute for a varied diet.

Storage

Store in a cool dry place.

Formulation

Suitable for Vegetarians.

General

E499

See for yourself

Super Strength Bilberry 6000 mg by Simply Supplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Super Strength Bilberry 6000 mg by Simply Supplements

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Bilberry extract

Interacts with
275 drugs
600 mg per serving

Bilberry is a blueberry-like fruit rich in antioxidant plant compounds called anthocyanins, and it has a long history of traditional use for eye healt...

Bilberry extract monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Dicalcium Phosphate, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Super Strength Bilberry 6000 mg by Simply Supplements Drug Interactions

Want to check YOUR meds against Super Strength Bilberry 6000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
275Drugs
275 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Super Strength Bilberry 6000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bilberry extract4 drug types · 275 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro, animal, and clinical research suggest that anthocyanidin extracts from bilberry can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, bilberry leaf or fruit extract may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that bilberry leaf extract might have blood glucose-lowering activity. Also, one small clinical trial in patients with type 2 diabetes shows that taking bilberry fruit extract 470 mg as a single dose prior to an oral glucose tolerance test lowers plasma glucose levels when compared with placebo.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Animal research shows that exposure to small concentrations of bilberry extract in drinking water for around one month increased CYP2E1 activity by 31%. However, exposure over a 2-month period did not increase CYP2E1 activity. This effect has not been reported in humans.

Likelihood Possible Evidence D
Erlotinib (Tarceva)

Theoretically, bilberry fruit extract might reduce the efficacy of erlotinib.
In vitro research suggests that bilberry fruit extract and its constituents, delphinidin and delphinidin-3-O-glucoside, inhibit the activity of erlotinib. This interaction has not been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Super Strength Bilberry 6000 mg, from the product label.

Simply Supplements

See all Simply Supplements products
Name
Simply Supplements
Street Address
PO Box 1330
City
Peterborough
ZipCode
PE2 2PW
Phone Number
0800 988 0292
Pharmacist Counseling Corner

Super Strength Bilberry 6000 mg by Simply Supplements: Common Questions

Does Super Strength Bilberry 6000 mg by Simply Supplements interact with any medications?
Yes. Based on its ingredients, Super Strength Bilberry 6000 mg has a known interaction with 275 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Super Strength Bilberry 6000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this bilberry supplement help my vision?
Night vision is actually rated Possibly Ineffective, so bilberry probably won't sharpen your sight. For other vision problems like macular degeneration, we don't have enough solid evidence to say whether it helps or not. Your eye doctor or pharmacist can point you toward treatments with better proof.
What are the side effects?
Most people tolerate bilberry well. The common ones are mild — dark or black stools, gas, and stomach discomfort. You might also notice your tongue or teeth turn dark blue or black temporarily, which is harmless. These effects usually settle down on their own.
Is this safe to take while I'm pregnant or breastfeeding?
Bilberry is rated Likely Safe during pregnancy and lactation, so safety data supports its use in those situations. Still, it's always smart to mention it to your doctor or pharmacist when you're pregnant or nursing, so they have a complete picture of what you're taking.
Can I take this with my blood thinner?
Not without checking with your pharmacist first. Bilberry may increase bleeding risk when combined with blood thinners or antiplatelet drugs like warfarin, aspirin, or clopidogrel. Use the medication checker on this page or ask your pharmacist before you start.
Will this affect my diabetes medication?
Possibly. Bilberry extract may lower blood sugar on its own, so mixing it with diabetes drugs could push your glucose too low. If you're on diabetes medication, run it through the checker below or talk to your pharmacist before taking this supplement.
How much bilberry is in each dose?
Each tablet contains 6000 mg of bilberry extract. The product is a single-ingredient supplement, so that's the only active ingredient you're getting — the rest are inactive binders and fillers.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Super Strength Bilberry 6000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Super Strength Bilberry 6000 mg label
Go deeper

The Full Monographs Behind Super Strength Bilberry 6000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Super Strength Bilberry 6000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bilberry 14 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Morazzoni P, Magistretti MJ. Activity of Myrtocyan, an anthosyanoside complex from Vaccinium myrtillus (VMA), on platelet aggregation and adhesiveness. Fitoterapia 1990;61:13-21.
  3. Erlund, I., Koli, R., Alfthan, G., Marniemi, J., Puukka, P., Mustonen, P., Mattila, P., and Jula, A. Favorable effects of berry consumption on platelet function, blood pressure, and HDL cholesterol. Am J Clin Nutr 2008;87(2):323-331. PubMed
  4. Hawrelak, J. A. and Myers, S. P. Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study. J Altern Complement Med 2010;16(10):1065-1071. PubMed
  5. Morazzoni P and Magistretti MJ. Effects of Vaccinium myrtillus anthocyanosides on prostacyclin-like activity in rat arterial issue. Fitoterapia 1986;57:11-14.
  6. Pulliero G, Montin S, Bettini V, and et al. Ex vivo study of the inhibitory effects of Vaccinium myrtillus anthocyanosides on human platelet aggregation. Fitoterapia 1989;60:69-75.
  7. Bottecchia D. Preliminary report on the inhibitory effect of vaccinium myrtillus anthocyanosides on platelet aggregation and clot retraction. Fitoterapia 1987;48:3-8.
  8. Fdez, M., Zaragoza, F., and Alvarez, P. In vitro platelet aggregation effects of anthocyanosides of vaccinium myrtilus L. Anales de la Real Academia de Farmacia 1983;49:79-90.
  9. Biedermann L, Mwinyi J, Scharl M, Frei P, Zeitz J, Kullak-Ublick GA, et al. Bilberry ingestion improves disease activity in mild to moderate ulcerative colitis-an open pilot study. 2013 May;7(4):271-9. PubMed
  10. Hoggard N, Cruickshank M, Moar KM, Bestwick C, Holst J, Russell W, et al. A single supplement of a standardized bilberry (Vaccinium myrtillus L.) extract (36% wet weight anthocyanins) modifies glycaemic response in individuals with type 2 diabetes control
  11. Aichinger G, Pahlke G, Nagel LJ, Berger W, Marko D. Bilberry extract, its major phenolic compounds, and soy isoflavone genistein antagonize the cytostatic drug erlotinib in human epithelial cells. Food Funct 2016;7(8):3628-36.
  12. Prokop J, Lněničková K, Cibicek N, et al. Effect of bilberry extract (Vaccinium myrtillus L.) on drug-metabolizing enzymes in rats. Food Chem Toxicol 2019;129:382-90. PubMed
  13. Chan SW, Chu TTW, Choi SW, Benzie IFF, Tomlinson B. Impact of short-term bilberry supplementation on glycemic control, cardiovascular disease risk factors, and antioxidant status in Chinese patients with type 2 diabetes. Phytother Res 2021. Online ahead o PubMed
  14. Bøhn SK, Myhrstad MCW, Thoresen M, et al. Bilberry/red grape juice decreases plasma biomarkers of inflammation and tissue damage in aged men with subjective memory impairment -a randomized clinical trial. BMC Nutr 2021;7(1):75. PubMed

See these in context on the Bilberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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