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Dietary supplement

Sweet Zap Mint Ingredients & Drug Interactions

by Seynani

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Sweet Zap Mint is a dietary supplement by Seynani with 2 active ingredients. Its ingredients are commonly taken for blood sugar support, type 2 diabetes, sugar cravings.Based on those ingredients, 920 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Gymnema sylvestre extract, Holy Basil extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Sweet Zap Mint by Seynani

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (1.23 mg) without saying how much of each component you get.

Sweet Zap Mint is a liquid with 2 active ingredients: gymnema sylvestre extract and holy basil extract. Gymnema has a long history in traditional medicine for blood sugar support, while holy basil is used in traditional practice for general wellness and stress.

The product also contains inactive ingredients — purified water, vegetable glycerin, peppermint oil, potassium sorbate, and silicon dioxide — which serve as the liquid base, preservative, and flavoring.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: End sugar cravings and support healthy sugar intake.
  • We looked for evidence on: Obesity, Metabolic syndrome, Diabetes, Impaired glucose tolerance (prediabetes), Sweet taste desensitization, Craving management.
  • The closest evidence on file: Gymnema is rated "Insufficient Reliable Evidence To Rate" for Diabetes (Natural Medicines).
  • Also on file: Gymnema is rated "Insufficient Reliable Evidence To Rate" for Obesity, Impaired glucose tolerance (prediabetes), Metabolic syndrome.
  • Also on file: Holy Basil is rated "Insufficient Reliable Evidence To Rate" for Diabetes, Obesity.

The evidence we hold doesn't establish that either ingredient works for its intended purposes. Gymnema is rated insufficient reliable evidence to rate for diabetes, prediabetes, obesity, and metabolic syndrome.

Holy basil similarly has insufficient reliable evidence for generalized anxiety, asthma, headache, respiratory infections, dental plaque, and diabetes. Neither ingredient has a proven effectiveness rating in our data.

The evidence, ingredient by ingredient Gymnema Holy Basil

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Gymnema is generally well tolerated short-term, but it can lower blood sugar — a real concern if you have diabetes or take blood sugar medications. Quality varies between products.

A rare case of drug-induced liver inflammation (hepatitis) has been reported with gymnema tea used heavily over 10 days; the patient recovered after 6 months with medical treatment. Holy basil is generally well tolerated short-term in adults, though long-term safety data are limited.

The most common side effects reported are loose stools and nausea. Gymnema is not recommended during pregnancy or while breastfeeding due to insufficient safety data.

Holy basil is rated possibly unsafe in pregnancy and should be avoided while breastfeeding as well.

Side effects, ingredient by ingredient Gymnema Holy Basil

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Gymnema, Holy Basil.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 921 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start Sweet Zap Mint, double-check with your doctor or pharmacist if you take antidiabetes medications — the risk of low blood sugar is moderate and real. Also flag blood thinners (anticoagulants) and antiplatelet drugs, which may carry increased bleeding risk.

If you take pentobarbital or any drug metabolized by your liver's CYP1A2, CYP2C9, or CYP3A4 systems, run it through the checker on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Sweet Zap Mint is not established to work for any condition in the data we hold. The bigger issue is that both ingredients interact with blood sugar medications and other drugs, and gymnema has documented liver safety concerns in rare cases.

If you take antidiabetes drugs, blood thinners, pentobarbital, or any CYP1A2, CYP2C9, or CYP3A4 substrate medications, you need to check with your doctor or pharmacist before using this product. Pregnant or breastfeeding people should not take it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sweet Zap Mint, straight from the product label.

Brand Seynani
Barcode (UPC) 697691508726
Net contents 0.27 Fluid Ounce(s); 8 mL
Market status On market
Date entered into DSLD Jan 22, 2021
DSLD ID 242602
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sweet Zap Mint by Seynani, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.104 mL
Maximum serving Sizes:
0.208 mL
Servings per container
77
UPC/BARCODE
697691508726
IngredientAmount% DV
Proprietary Blend1.23 mg--
Gymnema sylvestre extract0 NP--
Holy Basil extract0 NP--

Other ingredients: purified Water, Vegetable Glycerin, Peppermint Oil, Potassium Sorbate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Retrain Your Brain When you spray Sweet Zap on your tongue, the natural blend fills the sweet receptors located on the taste buds. Sweet Zap works on both sugar and artificial sweeteners by safely and temporarily blocking your ability to taste sweet. By blocking your ability to taste sweet, Sweet Zap can help retrain your brain to stop eating sweets altogether. Transitioning to a low or no-sugar diet reduces hunger and cravings, helps you burn fat, increases energy level, and reduces inflammation.

Sugar blocker mint spray

All natural no artificial flavors non-stimulant Gluten free Made with non-GMO ingredients

Suggested/Recommended/Usage/Directions

Sweet Zap is a conditioning tool. To increase your success: 1. Spray Sweet Zap on the tongue 2. Try the sweet you're craving

For regular use: Use 2-3 times daily or as often as needed. Sweet Zap is a conditioning tool. Suggested routine for success: If you eat sweets after breakfast or have sweets for breakfast, spray Sweet Zap and try that treat again. If you eat sweet treats after lunch, spray Sweet Zap after lunch and try that treat again. If you eat sweet treats after lunch, spray Sweet Zap after dinner or after you eat some of that dessert and try the dessert to avoid overeating.

Suggested Use: As a dietary supplement, spray Sweet Zap (1-2 times) directly on the tongue ensuring you cover the tip. Use Sweet Zap as often as needed to avoid cravings from sugar and artificial sweeteners and help maintain a healthy diet.

General Statements

End sugar cravings

Up to 77 servings

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to cure, diagnose, treat or prevent any disease.

See for yourself

Sweet Zap Mint by Seynani label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Sweet Zap Mint by Seynani

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.104 mL Dosage formLiquid Servings per container77 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

1.23 mg per serving

Other (inactive) ingredients: Purified Water, Vegetable Glycerin, Peppermint Oil, Potassium Sorbate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sweet Zap Mint by Seynani Drug Interactions

Want to check YOUR meds against Sweet Zap Mint?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
920Drugs
431 Moderate 489 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Sweet Zap Mint with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Gymnema sylvestre extract6 drug types · 851 drugs

Antidiabetes Drugs

Theoretically, taking gymnema with antidiabetes drugs might increase the risk of hypoglycemia.
Gymnema reduces blood glucose levels in some human and animal research. In human studies, it has been shown to enhance the blood glucose lowering effects of hypoglycemic drugs. However, other research in adults with prediabetes or metabolic syndrome suggests that gymnema does not reduce fasting levels of blood glucose. Until more is known, monitor blood glucose levels closely.

Likelihood Probable Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.
Animal and in vitro research shows that gymnema can inhibit the CYP1A2 enzyme. In one animal study, oral administration of gymnema for 7 days increased the plasma concentrations of phenacetin, a CYP1A2 substrate, by about 1.4-fold and reduced the clearance of phenacetin by about 29%.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, gymnema might increase or decrease levels of drugs metabolized by CYP2C9.
Animal research shows that gymnema can induce the CYP2C9 enzyme. In one animal study, gymnema caused a 2.4-fold increase in the clearance of tolbutamide, a CYP2C9 substrate, in rats. In vitro research also shows that gymnema can inhibit CYP2C9.

Likelihood Possible Evidence D
Phenacetin

Theoretically, taking gymnema with phenacetin might increase the levels of phenacetin.
Animal research shows that gymnema, administered orally for 7 days, decreases the clearance of phenacetin in a dose-dependent manner by about 21% to 29% and increases plasma levels about 1.3- to 1.4-fold when compared to control.

Likelihood Possible Evidence D
Tolbutamide (Orinase)

Theoretically, taking gymnema with tolbutamide might the decrease levels of tolbutamide.
Animal research shows that gymnema, administered orally for 7 days, increases the clearance of tolbutamide by 2.4-fold when compared to control.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, gymnema might increase levels of drugs metabolized by CYP3A4.
One in vitro study using rat liver microsomes shows that gymnema can modestly inhibit the CYP3A4 enzyme. However, other in vitro research using human liver microsomes shows that gymnema does not affect CYP3A4 activity. Animal research also shows that gymnema does not alter the function of CYP3A4. In one study in rats, oral administration of gymnema for 7 days did not alter the clearance of amlodipine, a CYP3A4 substrate.

Likelihood Unlikely Evidence D

Holy Basil extract3 drug types · 212 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Animal research shows that holy basil seed oil can prolong bleeding time, possibly due to inhibition of platelet aggregation. However, it is not known if this occurs in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, holy basil might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Small clinical studies show that taking holy basil can decrease fasting blood glucose and other measures of glycemic control in patients with type 2 diabetes.

Likelihood Possible Evidence B
Pentobarbital (Nembutal)

Theoretically, holy basil seed oil might increase the sedative effects of pentobarbital.
Animal research shows that holy basil seed oil increases pentobarbitone-induced sleeping time. However, it is not known if this occurs in humans or if this applies to other barbiturates or sedatives.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Sweet Zap Mint, from the product label.

Seynani

See all Seynani products
Name
Seynani, LLC
Street Address
PO Box 909
City
Falls Church
State
VA
ZipCode
22046
Pharmacist Counseling Corner

Sweet Zap Mint by Seynani: Common Questions

Does Sweet Zap Mint by Seynani interact with any medications?
Yes. Based on its ingredients, Sweet Zap Mint has a known interaction with 920 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sweet Zap Mint contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Sweet Zap Mint if I'm pregnant?
No. Gymnema has not been studied enough in pregnancy and is best avoided. Holy basil is rated possibly unsafe in pregnancy. Talk with your doctor or pharmacist for guidance on blood sugar support or other wellness goals during pregnancy.
Can I take Sweet Zap Mint while breastfeeding?
No. Neither gymnema nor holy basil has enough safety data for breastfeeding, so both are best avoided. Check with your doctor or pharmacist about safe alternatives.
What are the most common side effects?
Holy basil may cause loose stools and nausea — a small number of trial participants reported these. Gymnema is generally well tolerated short-term, though rare cases of serious liver inflammation have been reported with heavy use.
Does this product actually work for diabetes or blood sugar?
The evidence we hold doesn't establish that either ingredient reliably works for diabetes, prediabetes, or related conditions — both are rated insufficient reliable evidence. That said, gymnema can lower blood sugar in some people, which is why it interacts with diabetes medications.
Why is there a warning about blood thinners?
Holy basil seed oil can slow blood clotting in animal studies, which theoretically increases bleeding risk when combined with anticoagulants or antiplatelet drugs like warfarin or aspirin. Human data are limited, but it's important enough to check with your doctor or pharmacist if you take them.
What does 'gymnema lowers blood sugar' actually mean?
Gymnema can reduce how high your blood sugar gets, sometimes significantly. If you're already taking a medication that does the same thing, your blood sugar could drop too low (hypoglycemia), which is dangerous. That's why the interaction is moderate severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Sweet Zap Mint is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sweet Zap Mint label
Sources

Sources & How We Checked

Sweet Zap Mint's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 20 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gymnema 12 references
  1. Shanmugasundaram ER, Rajeswari G, Baskaran K, et al. Use of Gymnema sylvestre leaf extract in the control of blood glucose in insulin-dependent diabetes mellitus. J Ethnopharmacol 1990;30:281-94. PubMed
  2. Baskaran K, Kizar Ahamath B, Radha Shanmugasundaram K, Shanmugasundaram ER. Antidiabetic effect of leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients. J Ethnopharmacol 1990;30:295-300.
  3. Kamble B, Gupta A, Moothedath I, Khatal L, Janrao S, Jadhav A, et al. Effects of Gymnema sylvestre extract on the pharmacokinetics and pharmacodynamics of glimepiride in streptozotocin induced diabetic rats. Chem Biol Interact. 2016;245:30-8. PubMed
  4. Tiwari P, Mishra BN, Sangwan NS. Phytochemical and pharmacological properties of Gymnema sylvestre: an important medicinal plant. Biomed Res Int. 2014; 2014:830285.
  5. Fabio GD, Romanucci V, De Marco A, Zarrelli A. Triterpenoids from Gymnema sylvestre and their pharmacological activities. Molecules. 2014;19(8):10956-81. PubMed
  6. Shiyovich A, Sztarkier I, Nesher L. Toxic hepatitis induced by Gymnema sylvestre, a natural remedy for type 2 diabetes mellitus. Am J Med Sci. 2010;340(6):514-7. PubMed
  7. Zuniga LY, Gonzalez-Ortiz M, Martinez-Abundis E. Effect of gymnema sylvestre administration on metabolic syndrome, insulin sensitivity, and insulin secretion. J Med Food. 2017 Aug;20(8):750-54.
  8. Rammohan B, Samit K, Chinmoy D, et al. Human cytochrome P450 enzyme modulation by gymnema sylvestre: a predictive safety evaluation by LC-MS/MS. Pharmacogn Mag. 2016 Jul;12(Suppl 4):S389-S394.
  9. Vaghela M, Sahu N, Kharkar P, Pandita N. In vivo pharmacokinetic interaction by ethanolic extract of gymnema sylvestre with CYP2C9 (tolbutamide), CYP3A4 (amlodipine) and CYP1A2 (phenacetin) in rats. Chem Biol Interact. 2017 Dec 25;278:141-151. PubMed
  10. Vaghela M, Iyer K, Pandita N. In vitro inhibitory effect of gymnema sylvestre extracts and total gymnemic acids fraction on select cytochrome P450 activities in rat liver microsomes. Eur J Drug Metab Pharmacokinet. 2017 Oct 10. PubMed
  11. Gaytán Martínez LA, Sánchez-Ruiz LA, Zuñiga LY, González-Ortiz M, Martínez-Abundis E. Effect of Gymnema sylvestre administration on glycemic control, insulin secretion, and insulin sensitivity in patients with impaired glucose tolerance. J Med Food. 2021;
  12. Philips CA, Theruvath AH, Ravindran R. Toxic hepatitis-associated aplastic anaemia after dual homeopathic remedies and Gymnema sylvestre use. BMJ Case Rep 2022;15(3):e247867. PubMed

See these in context on the Gymnema monograph →

Holy Basil 8 references
  1. Agrawal P, Rai V, Singh RB. Randomized placebo-controlled, single blind trial of holy basil leaves in patients with noninsulin-dependent diabetes mellitus. Int J Clin Pharmacol Ther 1996;34:406-9.
  2. Sakina MR, Dandiya PC, Hamdard ME, Hameed A. Preliminary psychopharmacological evaluation of Ocimum sanctum leaf extract. J Ethnopharmacol 1990;28:143-50. PubMed
  3. Singh S, Rehan HM, Majumdar DK. Effect of Ocimum sanctum fixed oil on blood pressure, blood clotting time and pentobarbitone-induced sleeping time. J Ethnopharmacol 2001;78:139-43. PubMed
  4. Mondal, S., Varma, S., Bamola, V. D., Naik, S. N., Mirdha, B. R., Padhi, M. M., Mehta, N., and Mahapatra, S. C. Double-blinded randomized controlled trial for immunomodulatory effects of Tulsi (Ocimum sanctum Linn.) leaf extract on healthy volunteers. J PubMed
  5. Agarwal, P. and Nagesh, L. Comparative evaluation of efficacy of 0.2% Chlorhexidine, Listerine and Tulsi extract mouth rinses on salivary Streptococcus mutans count of high school children--RCT. Contemp.Clin Trials 2011;32(6):802-808. PubMed
  6. Vohora, S. B., Garg, S. K., and Chaudhury, R. R. Antifertility screening of plants. 3. Effect of six indigenous plants on early pregnancy in albino rats. Indian J Med Res 1969;57(5):893-899.
  7. Khanna S, Gupta SR, Grover JK. Effect of long term feeding of tulsi (Ocimum sanctum Linn) on reproductive performance of adult albino rats. Indian J Exp Biol 1986;24(5):302-4.
  8. Somasundaram G, Manimekalai K, Salwe KJ, Pandiamunian J. Evaluation of the antidiabetic effect of Ocimum sanctum in type 2 diabetes patients. Int J Life Sci Pharma Res 2012;2(3):75-81.

See these in context on the Holy Basil monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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